Research
Read how they describe their research on their McGill University profile.
Latest papers
Disruption of SND1-MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells In Vitro and In Vivo.
Molecular cancer therapeutics · 2021
Design, synthesis and antibacterial evaluation of 2,4-disubstituted-6-thiophenyl-pyrimidines.
European journal of medicinal chemistry · 2019
Perspectives on the recent developments with green tea polyphenols in drug discovery.
Expert opinion on drug discovery · 2018
Latest funding
- $300,000
Evaluation of novel flavonoids in models of hematological cancer
CIHR · 2011 · Nominated PI
- $120,000
Ionic-liquid-supported synthesis
NSERC · 2007 · Principal investigator
- $35,000
Ionic liquids supported synthesis
NSERC · 2006 · Principal investigator
11 publications.
Disruption of SND1-MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells In Vitro and In Vivo.
Li P, He Y, Chen T, Choy KY, Chow TS, Wong ILK, Yang X, Sun W, Su X, Chan TH, Chow LMC
Design, synthesis and antibacterial evaluation of 2,4-disubstituted-6-thiophenyl-pyrimidines.
Fang Z, Zheng S, Chan KF, Yuan W, Guo Q, Wu W, Lui HK, Lu Y, Leung YC, Chan TH, Wong KY, Sun N
Perspectives on the recent developments with green tea polyphenols in drug discovery.
Li F, Wang Y, Li D, Chen Y, Qiao X, Fardous R, Lewandowski A, Liu J, Chan TH, Dou QP
Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells.
Heyza JR, Arora S, Zhang H, Conner KL, Lei W, Floyd AM, Deshmukh RR, Sarver J, Trabbic CJ, Erhardt P, Chan TH, Dou QP, Patrick SM
(-)-Epiafzelechin Protects against Ovariectomy-induced Bone Loss in Adult Mice and Modulate Osteoblastic and Osteoclastic Functions In Vitro.
Wong KC, Cao S, Dong X, Law MC, Chan TH, Wong MS
Biological and Mechanistic Characterization of Novel Prodrugs of Green Tea Polyphenol Epigallocatechin Gallate Analogs in Human Leiomyoma Cell Lines.
Ahmed RS, Liu G, Renzetti A, Farshi P, Yang H, Soave C, Saed G, El-Ghoneimy AA, El-Banna HA, Foldes R, Chan TH, Dou QP
Aerobic and electrochemical oxidative cross-dehydrogenative-coupling (CDC) reaction in an imidazolium-based ionic liquid.
Baslé O, Borduas N, Dubois P, Chapuzet JM, Chan TH, Lessard J, Li CJ
Collision-induced dissociation of sulfur-containing imidazolium ionic liquids.
Lesimple A, He X, Chan TH, Mamer O
Oligonucleotide Synthesis Using Ionic Liquids as Soluble Supports
Robert A. Donga, Matthew R. Hassler, Tak Hang Chan, Masad José Damha
A Novel Approach to Oligonucleotide Synthesis Using an Imidazolium Ion Tag as a Soluble Support
Robert A. Donga, Syed M. Khaliq‐Uz‐Zaman, Tak Hang Chan, Masad José Damha
Evaluation of novel flavonoids in models of hematological cancer
Principal investigators: Chan, Tak Hang
Keywords: Apoptosis; Cell Proliferation; Chronic Lymphocytic Leukemia; Egcg; Flavonoid; Green Tea; Multiple Myeloma; Prodrug; Proteasome; Xenograft
Ionic-liquid-supported synthesis
Principal investigators: Chan, TakHang
Ionic liquids supported synthesis
Principal investigators: Chan, TakHang
A 5mm PFG dual broadband probe for a 500 MHz NMR
Principal investigators: Gleason, James
Switchable probe for 400 MHz NMR spectrometer
Principal investigators: Chan, TakHang
The Canadian Green Chemistry Network (CGCN) - Towards a Bio-based Economy with Sustainable Materials and Renewable Technology (BIOSMART)
Principal investigators: Chan, TakHang
Exploration of ionic liquids as soluble supports for organic synthesis
Principal investigators: Chan, TakHang
Organometallic reactions in aqueous media
Principal investigators: Chan, TakHang
Organometallic reactions in aqueous media
Principal investigators: Chan, TakHang
300 MHz nuclear magnetic resonance spectrometer
Principal investigators: Lennox, Bruce
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
- Chao-Jun Li and C.J. Li: 978 shared papers
- Masad Damha and Tak-Hang Chan: 2 shared papers
- Chao-Jun Li and Nadine Borduas-Dedekind: 1 shared paper
- Chao-Jun Li and Tak-Hang Chan: 1 shared paper
- Chao-Jun Li and Jean Lessard: 1 shared paper
- Nadine Borduas-Dedekind and C.J. Li: 1 shared paper
- Nadine Borduas-Dedekind and Tak-Hang Chan: 1 shared paper
- Nadine Borduas-Dedekind and Jean Lessard: 1 shared paper
- C.J. Li and Tak-Hang Chan: 1 shared paper
- C.J. Li and Jean Lessard: 1 shared paper
- Tak-Hang Chan and Jean Lessard: 1 shared paper
- Department of Chemistry
- UBC Chemistry
- Other
Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.