Philippe Tessier, Université Laval

Research

Cytokines S100 Proteins Arthritis Immunosuppression In Vivo Model T Cells Animal Models Drug Development

Latest papers

Tumor-Associated Macrophages Enhance Tumor Hypoxia and Aerobic Glycolysis.
Cancer research · 2019
S100A9 potentiates the activation of neutrophils by the etiological agent of gout, monosodium urate crystals.
Journal of leukocyte biology · 2017
Surface RANKL of Toll-like receptor 4-stimulated human neutrophils activates osteoclastic bone resorption.
Blood · 2009

All 4 publications

Latest funding

Surveillance des réponses immunitaires au vaccin contre la COVID-19 chez les personnes vivant avec le VIH-1
CIHR · 2021 · Principal investigator
$500,000
Developing synthetic S100A9-based molecules for differentiation therapy of human acute myeloid leukemia
CIHR · 2021 · Nominated PI
$753,525
Biology of S100A8 and S100A9 proteins in Human Acute Myeloid Leukemia
CIHR · 2019 · Co-investigator
$761,176

All 12 grants and awards

4 publications.

01

Tumor-Associated Macrophages Enhance Tumor Hypoxia and Aerobic Glycolysis.

Jeong H, Kim S, Hong BJ, Lee CJ, Kim YE, Bok S, Oh JM, Gwak SH, Yoo MY, Lee MS, Chung SJ, Defrêne J, Tessier P, Pelletier M, Jeon H, Roh TY, Kim B, Kim KH, Ju JH, Kim S, Lee YJ, Kim DW, Kim IH, Kim HJ, Park JW, Lee YS, Lee JS, Cheon GJ, Weissman IL, Chung DH, Jeon YK, Ahn GO

Cancer research2019

DOI: 10.1158/0008-5472.can-18-2545 PMID: 30610087

02

S100A9 potentiates the activation of neutrophils by the etiological agent of gout, monosodium urate crystals.

Rousseau LS, Paré G, Lachhab A, Naccache PH, Marceau F, Tessier P, Pelletier M, Fernandes M

Journal of leukocyte biology2017

DOI: 10.1189/jlb.3ma0117-020r PMID: 28550118

03

Surface RANKL of Toll-like receptor 4-stimulated human neutrophils activates osteoclastic bone resorption.

Chakravarti A, Raquil MA, Tessier P, Poubelle PE

Blood2009

DOI: 10.1182/blood-2008-09-178301 PMID: 19546479

04

Immunogenicity of papaya mosaic virus-like particles fused to a hepatitis C virus epitope: evidence for the critical function of multimerization.

Denis J, Majeau N, Acosta-Ramirez E, Savard C, Bedard MC, Simard S, Lecours K, Bolduc M, Pare C, Willems B, Shoukry N, Tessier P, Lacasse P, Lamarre A, Lapointe R, Lopez Macias C, Leclerc D

Virology2007

DOI: 10.1016/j.virol.2007.01.011 PMID: 17320136

Surveillance des réponses immunitaires au vaccin contre la COVID-19 chez les personnes vivant avec le VIH-1

Principal investigatorCIHR2021Op. Gr.:Emerging COVID-19 Res. Gaps & Priorities - HIV and SARS-CoV-2

Principal investigators: Gilbert, Caroline; Pelletier, Martin; Pouliot, Marc; Tessier, Philippe A

Keywords: Cytokines; Immunité Cellulaire; Inflammation; Net; Neutrophile; Sars-Cov-2; Sérologie; Tlr7/8; Vaccin; Vih-1

$500,000

Developing synthetic S100A9-based molecules for differentiation therapy of human acute myeloid leukemia

Nominated PICIHR2021Project Grant

Principal investigators: Tessier, Philippe A

Keywords: Animal Models; Drug Development; Leukemia; Myeloid Cells; Protein Structure; S100 Proteins

$753,525

Biology of S100A8 and S100A9 proteins in Human Acute Myeloid Leukemia

Co-investigatorCIHR2019Project Grant

Principal investigators: Barabé, Frédéric

Keywords: Acute Myeloid Leukemia; Differentiation Therapy; Human Primary Samples; In Vivo Models Of Leukemia; Leukemic Stem Cells; Mll Leukemias; S100a8 - S100a9 Proteins And Antibodies; Tlr Receptors And Pathways; Xenotransplantation In Immunodeficient Mice

$761,176

The characterization of MICL, a novel negative regulator of the immune response in arthritis.

Co-investigatorCIHR2015Operating Grant

Principal investigators: Fernandes, Maria J

Keywords: Autoantibodies; C-Type Lectin Receptors; Citrullination; Cytokines; Inflammation; Inhibitory Receptors; Neutrophils; Receptor Ligand; Rheumatoid Arthritis; Signalling

$640,500

Immunosuppressive function of S100A8 in arthritis

Nominated PICIHR2014Operating Grant

Principal investigators: Tessier, Philippe A

Keywords: Arthritis; Cytokines; Immunosuppression; In Vivo Model; S100 Proteins; T Cells

$650,907

Immunosuppressive function of S100A8 in arthritis

Nominated PICIHR2013Operating Grant - PA: Musculoskeletal Health, Arthritis, Skin and Oral Health

Principal investigators: Tessier, Philippe A

Keywords: Arthritis; Cytokines; Immunosuppression; In Vivo Model; S100 Proteins; T Cells

$100,000

Canada-Australia collaborative studies on chronic inflammation

Nominated PICIHR2011Planning Grants - Priority Announcement: Infection and Immunity

Principal investigators: Tessier, Philippe A

Keywords: Asthma; Chronic; Diabetes; Heart Disease; Immunology; Inflammation; Rheumatology

$24,400

Study of the mechanism of secretion of calprotectin

Nominated PICIHR2010Operating Grant

Principal investigators: Tessier, Philippe A

Keywords: Arthritis; Cell Culture; Cytokine; Elisa; Inflammation; Secretion

$389,400

Identification and validation of new therapeutic targets for autoimmune diseases

Principal investigatorNSERC2009Collaborative Health Research Projects

Principal investigators: Tessier, Philippe

$200,200

Development of anti-S100 proteins for the treatment of arthritis

Nominated PICIHR2009Proof of Principle Program - Phase I

Principal investigators: Tessier, Philippe A

Keywords: Arthritis; Elisas; In Vivo Models; Inflammation

$142,600

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Microbiology and Immunology
Microbiologie et d'infectiologie
Other

Co-authors at Université Laval, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Martin Pelletier

Microbiology and Immunology

2 shared papers, latest 2019

Maria Fernandes

Faculty

1 shared papers, latest 2017

Denis Leclerc

Microbiologie et d'infectiologie

1 shared papers, latest 2007

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2021

Subject: Prospective PhD student: Cytokines Dear Professor Tessier, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Tumor-Associated Macrophages Enhance Tumor Hypoxia and Aerobic Glycolysis." (2019), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Surveillance des réponses immunitaires au vaccin contre la COVID-19 chez les personnes vivant avec le VIH-1" (2021), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]