Guy Lemay, Université de Montréal

Latest papers

Microbiological and rheological dynamics of mixed biofilms formed by bacteria and eukaryotic virus.
Scientific reports · 2026
The reovirus μ2 protein, an enigmatic multifunctional protein with numerous secrets yet to be uncovered.
Virology · 2025 · first author
How Many Mammalian Reovirus Proteins are involved in the Control of the Interferon Response?
Pathogens (Basel, Switzerland) · 2019 · senior author

All 11 publications

Latest funding

Microbiological and rheological insights at the formation and disruption of model and clinical bacteria-virus mixed biofilms
SSHRC · 2022 · Co-investigator
$125,000
Development of an Oral Reovirus-Based Vaccination Platform for COVID-19.
NSERC · 2020 · Co-investigator
$50,000
A Seahorse analyzer for the multiparametric study of cellular metabolism in prokaryotes and eukaryotes.
NSERC · 2020 · Co-investigator
$150,000

All 11 grants and awards

11 publications.

01

Microbiological and rheological dynamics of mixed biofilms formed by bacteria and eukaryotic virus.

Gao J, Abriat C, Laekas-Hameder M, Virgilio N, Dozois CM, Quach C, Heuzey MC, Lemay G, Daigle F

Scientific reports2026

DOI: 10.1038/s41598-026-39314-9 PMID: 41673237

02

The reovirus μ2 protein, an enigmatic multifunctional protein with numerous secrets yet to be uncovered.

Lemay G, Boudreault S

Virology2025First author

DOI: 10.1016/j.virol.2024.110275 PMID: 39515007

03

How Many Mammalian Reovirus Proteins are involved in the Control of the Interferon Response?

Lanoie D, Boudreault S, Bisaillon M, Lemay G

Pathogens (Basel, Switzerland)2019Senior author

DOI: 10.3390/pathogens8020083 PMID: 31234302

04

A single mutation in the mammalian orthoreovirus S1 gene is responsible for increased interferon sensitivity in a virus mutant selected in Vero cells.

Lanoie D, Côté S, Degeorges E, Lemay G

Virology2019Senior author

DOI: 10.1016/j.virol.2018.12.010 PMID: 30578938

05

Synthesis and Translation of Viral mRNA in Reovirus-Infected Cells: Progress and Remaining Questions.

Lemay G

Viruses2018First author

DOI: 10.3390/v10120671 PMID: 30486370

06

Multiple proteins differing between laboratory stocks of mammalian orthoreoviruses affect both virus sensitivity to interferon and induction of interferon production during infection.

Lanoie D, Lemay G

Virus research2018Senior author

DOI: 10.1016/j.virusres.2018.01.009 PMID: 29382551

07

Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions.

Boudreault S, Martenon-Brodeur C, Caron M, Garant JM, Tremblay MP, Armero VE, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Lemay G, Bisaillon M

PloS one2016

DOI: 10.1371/journal.pone.0161914 PMID: 27598998

08

A single amino acid substitution in the mRNA capping enzyme λ2 of a mammalian orthoreovirus mutant increases interferon sensitivity.

Sandekian V, Lemay G

Virology2015Senior author

DOI: 10.1016/j.virol.2015.04.020 PMID: 25985441

09

Amino acids substitutions in σ1 and μ1 outer capsid proteins of a Vero cell-adapted mammalian orthoreovirus are required for optimal virus binding and disassembly.

Sandekian V, Lemay G

Virus research2015Senior author

DOI: 10.1016/j.virusres.2014.11.002 PMID: 25445342

10

Further characterization and determination of the single amino acid change in the tsI138 reovirus thermosensitive mutant.

Lemay G, Bisaillon M

Canadian journal of microbiology2012First author

DOI: 10.1139/w2012-033 PMID: 22510042

Microbiological and rheological insights at the formation and disruption of model and clinical bacteria-virus mixed biofilms

Co-investigatorSSHRC2022New Frontiers in Research Fund - Exploration

Principal investigators: DAIGLE, France

Keywords: biofilm; rheology; bacteria; virus; bacteria-virus; antimicrobial resistance; antimicrobial synthesis; nanoparticle; clinical persistence

$125,000

Development of an Oral Reovirus-Based Vaccination Platform for COVID-19.

Co-investigatorNSERC2020Alliance Grants

Principal investigators: Alain, Tommy

$50,000

A Seahorse analyzer for the multiparametric study of cellular metabolism in prokaryotes and eukaryotes.

Co-investigatorNSERC2020Research Tools and Instruments

Principal investigators: Thibodeau, Jacques

$150,000

Molecular dissection studies of mammalian reovirus proteins using reverse genetics.

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Lemay, Guy

$168,000

Reverse genetics study of mammalian reovirus proteins: fundamental studies and possible applications

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Lemay, Guy

$130,000

Molecular study of reovirus outer capsid proteins: fundamental aspects and applications.

Principal investigatorNSERC2007Discovery Grants Program - Individual

Principal investigators: Lemay, Guy

$150,000

Canadian Network for Vaccines and Immunotherapeutics of Cancer and Chronic Viral Diseases (CANVAC) (2006 Renewal Competition)

Co-investigatorNSERC2006Networks of Centres of Excellence

Principal investigators: Sekaly, RafickPierre

$3,999,490

Imaging system for DNA, RNA and proteins

Principal investigatorNSERC2006Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Lemay, Guy

$150,000

Molecular study of reovirus capsid proteins:fundamental aspects and applications.

Principal investigatorNSERC2002Discovery Grants Program - Individual

Principal investigators: Lemay, Guy

$150,000

Canadian Network for Vaccines and Immunotherapeutics of Cancer and Chronic Viral Diseases (CANVAC)

Co-investigatorNSERC1999Networks of Centres of Excellence

Principal investigators: Sekaly, RafickPierre

$8,225,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Microbiologie, Infectiologie et Immunologie
Biochimie
Département de santé buccale
Microbiologie, infectiologie et immunologie
Dept de biochimie
Other

Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

France DAIGLE

Microbiologie, infectiologie et immunologie

1 shared papers, latest 2026

Jean-Pierre Perreault

Dept de biochimie

1 shared papers, latest 2016

Caroline Quach

Département de santé buccale

1 shared papers, latest 2026

Write to this professor

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Paper to mention

Subject: Prospective PhD student Dear Professor Lemay, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Microbiological and rheological dynamics of mixed biofilms formed by bacteria and eukaryotic virus." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Guy Lemay

Latest papers

Latest funding

Microbiological and rheological dynamics of mixed biofilms formed by bacteria and eukaryotic virus.

The reovirus μ2 protein, an enigmatic multifunctional protein with numerous secrets yet to be uncovered.

How Many Mammalian Reovirus Proteins are involved in the Control of the Interferon Response?

A single mutation in the mammalian orthoreovirus S1 gene is responsible for increased interferon sensitivity in a virus mutant selected in Vero cells.

Synthesis and Translation of Viral mRNA in Reovirus-Infected Cells: Progress and Remaining Questions.

Multiple proteins differing between laboratory stocks of mammalian orthoreoviruses affect both virus sensitivity to interferon and induction of interferon production during infection.

Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions.

A single amino acid substitution in the mRNA capping enzyme λ2 of a mammalian orthoreovirus mutant increases interferon sensitivity.

Amino acids substitutions in σ1 and μ1 outer capsid proteins of a Vero cell-adapted mammalian orthoreovirus are required for optimal virus binding and disassembly.

Further characterization and determination of the single amino acid change in the tsI138 reovirus thermosensitive mutant.

Microbiological and rheological insights at the formation and disruption of model and clinical bacteria-virus mixed biofilms

Development of an Oral Reovirus-Based Vaccination Platform for COVID-19.

A Seahorse analyzer for the multiparametric study of cellular metabolism in prokaryotes and eukaryotes.

Molecular dissection studies of mammalian reovirus proteins using reverse genetics.

Reverse genetics study of mammalian reovirus proteins: fundamental studies and possible applications

Molecular study of reovirus outer capsid proteins: fundamental aspects and applications.

Canadian Network for Vaccines and Immunotherapeutics of Cancer and Chronic Viral Diseases (CANVAC) (2006 Renewal Competition)

Imaging system for DNA, RNA and proteins

Molecular study of reovirus capsid proteins:fundamental aspects and applications.

Canadian Network for Vaccines and Immunotherapeutics of Cancer and Chronic Viral Diseases (CANVAC)

Frequent collaborators

Martin Bisaillon

Simon Boudreault

France DAIGLE

Jean-Pierre Perreault

Caroline Quach

Guy Lemay

Latest papers

Latest funding

Microbiological and rheological dynamics of mixed biofilms formed by bacteria and eukaryotic virus.

The reovirus &#x3bc;2 protein, an enigmatic multifunctional protein with numerous secrets yet to be uncovered.

How Many Mammalian Reovirus Proteins are involved in the Control of the Interferon Response?

A single mutation in the mammalian orthoreovirus S1 gene is responsible for increased interferon sensitivity in a virus mutant selected in Vero cells.

Synthesis and Translation of Viral mRNA in Reovirus-Infected Cells: Progress and Remaining Questions.

Multiple proteins differing between laboratory stocks of mammalian orthoreoviruses affect both virus sensitivity to interferon and induction of interferon production during infection.

Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions.

A single amino acid substitution in the mRNA capping enzyme &#x3bb;2 of a mammalian orthoreovirus mutant increases interferon sensitivity.

Amino acids substitutions in &#x3c3;1 and &#x3bc;1 outer capsid proteins of a Vero cell-adapted mammalian orthoreovirus are required for optimal virus binding and disassembly.

Further characterization and determination of the single amino acid change in the tsI138 reovirus thermosensitive mutant.

Microbiological and rheological insights at the formation and disruption of model and clinical bacteria-virus mixed biofilms

Development of an Oral Reovirus-Based Vaccination Platform for COVID-19.

A Seahorse analyzer for the multiparametric study of cellular metabolism in prokaryotes and eukaryotes.

Molecular dissection studies of mammalian reovirus proteins using reverse genetics.

Reverse genetics study of mammalian reovirus proteins: fundamental studies and possible applications

Molecular study of reovirus outer capsid proteins: fundamental aspects and applications.

Canadian Network for Vaccines and Immunotherapeutics of Cancer and Chronic Viral Diseases (CANVAC) (2006 Renewal Competition)

Imaging system for DNA, RNA and proteins

Molecular study of reovirus capsid proteins:fundamental aspects and applications.

Canadian Network for Vaccines and Immunotherapeutics of Cancer and Chronic Viral Diseases (CANVAC)

Frequent collaborators

Martin Bisaillon

Simon Boudreault

France DAIGLE

Jean-Pierre Perreault

Caroline Quach

The reovirus μ2 protein, an enigmatic multifunctional protein with numerous secrets yet to be uncovered.

A single amino acid substitution in the mRNA capping enzyme λ2 of a mammalian orthoreovirus mutant increases interferon sensitivity.

Amino acids substitutions in σ1 and μ1 outer capsid proteins of a Vero cell-adapted mammalian orthoreovirus are required for optimal virus binding and disassembly.