This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Effects of polyphenol supplementation on hepatic steatosis, intima-media thickness and non-invasive vascular elastography in obese adolescents: a pilot study protocol.
BMJ open · 2024
Early predictors of unfavourable outcome in progressive cholestasis of northwestern Quebec.
Canadian liver journal · 2022 · senior author
Leveraging interacting signaling pathways to robustly improve the quality and yield of human pluripotent stem cell-derived hepatoblasts and hepatocytes.
Stem cell reports · 2022 · senior author
Latest funding
- $963,900
Germline DNMT3A loss-of-function alters histone H3K27 methylation and causes neuronal impairments
CIHR · 2024 · Co-investigator
- $80,000
Using stem cell-derived liver organoids to clarify the mechanisms underlying human liver regeneration
NSERC · 2023 · Principal investigator
- $100,000
Germline DNMT3A loss-of-function alters PRC2-dependent H3K27me3 deposition and leads to neuronal impairments.
CIHR · 2023 · Co-investigator
11 publications.
Effects of polyphenol supplementation on hepatic steatosis, intima-media thickness and non-invasive vascular elastography in obese adolescents: a pilot study protocol.
Moretti JB, Drouin A, Truong C, Youn E, Cloutier A, Alvarez F, Paganelli M, Grzywacz K, Jantchou P, Dubois J, Levy E, El Jalbout R
Early predictors of unfavourable outcome in progressive cholestasis of northwestern Quebec.
Khendek L, Diaz C, Drouin E, Lallier M, Alvarez F, Paganelli M
Leveraging interacting signaling pathways to robustly improve the quality and yield of human pluripotent stem cell-derived hepatoblasts and hepatocytes.
Raggi C, M'Callum MA, Pham QT, Gaub P, Selleri S, Baratang NV, Mangahas CL, Cagnone G, Reversade B, Joyal JS, Paganelli M
Generation of Complex Syngeneic Liver Organoids from Induced Pluripotent Stem Cells to Model Human Liver Pathophysiology.
Raggi C, Selleri S, M'Callum MA, Paganelli M
High-throughput assessment of mutations generated by genome editing in induced pluripotent stem cells by high-resolution melting analysis.
Pham QT, Raad S, Mangahas CL, M'Callum MA, Raggi C, Paganelli M
Non-alcoholic fatty liver disease severity and metabolic complications in obese children: impact of omega-3 fatty acids.
Spahis S, Alvarez F, Ahmed N, Dubois J, Jalbout R, Paganelli M, Grzywacz K, Delvin E, Peretti N, Levy E
Acute Liver Failure: How Intensive Should Be the Care?
Savy N, Paganelli M, Jouvet P
Successful Liver Transplants for Liver Failure Associated With Pyruvate Kinase Deficiency.
Chartier ME, Hart L, Paganelli M, Ahmed N, Bilodeau M, Alvarez F
Predisposing Factors for Spontaneous Closure of Congenital Portosystemic Shunts.
Paganelli M, Lipsich JE, Sciveres M, Alvarez F
Anti-CD20 treatment of giant cell hepatitis with autoimmune hemolytic anemia.
Paganelli M, Patey N, Bass LM, Alvarez F
Germline DNMT3A loss-of-function alters histone H3K27 methylation and causes neuronal impairments
Principal investigators: McGraw, Serge
Keywords: Brain Development; Cortical Organoids; Dna Methyltransferase 3a (Dnmt3a); Epigenetics; Induced Pluripotent Stem Cells (Ipsc); Ipsc Derived Models; Mouse Model; Multiomics; Polycomb Repressive Complex 2 (Prc2)
Using stem cell-derived liver organoids to clarify the mechanisms underlying human liver regeneration
Principal investigators: Paganelli, Massimiliano
Keywords: liver regeneration; liver organoids; notch signalling; human models; induced pluripotent stem cells; engineered tissues
Germline DNMT3A loss-of-function alters PRC2-dependent H3K27me3 deposition and leads to neuronal impairments.
Principal investigators: McGraw, Serge
Keywords: Bioinformatics; Brain Development; Dna Methyltransferase 3a (Dnmt3a); Epigenetics; Induced Pluripotent Stem Cells (Ipsc); Mouse Model; Multiomic Approaches; Polycomb Repressive Complex 2 (Prc2)
Hepatitis B virus-mediated liver inflammation induces a novel monocyte-derived macrophage with an inflammatory profile to drive hepatitis B pathogenesis.
Principal investigators: Gehring, Adam J
Keywords: Hepatitis B Virus; Human; Inflammation; Liver; Macrophage; Organoids; Stem Cells
Definition of a novel monocyte-derived macrophage population in the inflamed human liver.
Principal investigators: Gehring, Adam J
Keywords: Hepatitis B Virus; Human; Inflammation; Liver; Macrophage; Organoids; Stem Cells
Stem cell-derived Encapsulated Liver Tissue to treat liver failure without immunosuppression: technology maturation towards clinical translation
Principal investigators: Paganelli, Massimiliano
Keywords: Commercialization; Liver Failure; Liver Organoids; Product Development; Regenerative Medicine; Stem Cell-Derived Tissues; Technology Transfer
Heterologous stem cell therapy to treat acute liver failure in infants, children and adolescents without the need of immunosuppression
Principal investigators: Paganelli, Massimiliano
Keywords: Acute Liver Failure; Induced Pluripotent Stem Cells; Liver Organoids; Stem Cell Therapy
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Emile Levy and Prévost Jantchou: 2 shared papers
- Emile Levy and Massimiliano Paganelli: 2 shared papers
- Prévost Jantchou and Massimiliano Paganelli: 1 shared paper
- Massimiliano Paganelli and Philippe Jouvet: 1 shared paper
- Pediatrics
- Nutrition
- Other
Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.