Shirin Golchi, Université de Montréal

Research

Adaptive Trials Hiv Implementation Science Stbbi Training

Latest papers

Protecting the brain from post-stroke cognitive impairment and dementia with multimodal exercise training: study protocol for a Bayesian adaptive trial (PROTECT)
BMJ Open · 2026
A digital twin methodology using retrospective patient data for sample size reduction in Alzheimer's disease clinical trials.
Alzheimer's research & therapy · 2026
Bayesian optimization for identification of optimal biological dose combinations in personalized dose-finding trials.
Biometrics · 2026

All 16 publications

Latest funding

Building Capacity in Innovative Adaptive Trial Designs for HIV and STBBI Research: The CTN-Québec Training Platform
CIHR · 2025 · Principal investigator
$800,000
Randomized Double-Blind Placebo-Controlled Clinical Trial to Assess the Efficacy of Mycophenolate Mofetil in Subclinical Interstitial Lung Disease Associated with Systemic Sclerosis: a Feasibility Study
CIHR · 2022 · Co-investigator
$346,640
PRevention of COVID-19 with high dose Oral Vitamin D supplemental Therapy in Essential healthCare Teams (PROTECT)
CIHR · 2020 · Co-investigator
$4,224,996

All 3 grants and awards

16 publications.

01

Protecting the brain from post-stroke cognitive impairment and dementia with multimodal exercise training: study protocol for a Bayesian adaptive trial (PROTECT)

Moncion K, Rodrigues L, Bon A, Sutoski A, Sikorska K, Allison EY, Abreu J, Golchi S, Arbour N, Gauthier C

BMJ Open2026

DOI: 10.1136/bmjopen-2026-123336

02

A digital twin methodology using retrospective patient data for sample size reduction in Alzheimer's disease clinical trials.

Andrews D, Golchi S, Collins DL, Alzheimer’s Disease Neuroimaging Initiative

Alzheimer's research & therapy2026

DOI: 10.1186/s13195-026-02024-5 PMID: 42046101

03

Bayesian optimization for identification of optimal biological dose combinations in personalized dose-finding trials.

Willard J, Golchi S, Moodie EEM

Biometrics2026

DOI: 10.1093/biomtc/ujag152 PMID: 42720978

04

Design of Bayesian Clinical Trials With Clustered Data.

Hagar L, Golchi S

Statistics in medicine2026Senior author

DOI: 10.1002/sim.70488 PMID: 41820232

05

Two-stage Bayesian network meta-analysis of individualized treatment rules for multiple treatments with siloed data.

Shen J, Moodie EE, Golchi S

Statistical methods in medical research2026Senior author

DOI: 10.1177/09622802251387430 PMID: 41134973

06

Discussion on ''Nonparanormal Adjusted Marginal Inference'' by Susanne Dandl and Torsten Hothorn.

Golchi S

Biometrics2026First author

DOI: 10.1093/biomtc/ujag066 PMID: 42053276

07

Training the next generation of clinical trial biostatisticians

Parpia S, Dobinson J, Heath A, Wong H, Thorpe K, Sajobi T, Golchi S, Mbuagbaw L, Lee SF, Ho T

Clinical Trials2025

DOI: 10.1177/17407745251361741

08

CAEP 2024 Academic Symposium: adaptive platform trials in emergency medicine in Canada.

Germain N, Audet M, Graves L, Murthy S, McLeod SL, Khangura J, Golchi S, McRae AD, Hohl CM, Cheng I, Olivier Chevrier G, Marshall JC, Archambault PM, APTs in Emergency Medicine Group

CJEM2025

DOI: 10.1007/s43678-025-00874-w PMID: 40295353

09

Artificial Intelligence in Depression-Medication Enhancement (AID-ME): A Cluster Randomized Trial of a Deep-Learning-Enabled Clinical Decision Support System for Personalized Depression Treatment Selection and Management.

Benrimoh D, Whitmore K, Richard M, Golden G, Perlman K, Jalali S, Friesen T, Barkat Y, Mehltretter J, Fratila R, Armstrong C, Israel S, Popescu C, Karp JF, Parikh SV, Golchi S, Moodie EEM, Shen J, Gifuni AJ, Ferrari M, Sapra M, Kloiber S, Pinard GF, Dunlop BW, Looper K, Ranganathan M, Enault M, Beaulieu S, Rej S, Hersson-Edery F, Steiner W, Anacleto A, Qassim S, McGuire-Snieckus R, Margolese HC

The Journal of clinical psychiatry2025

DOI: 10.4088/jcp.24m15634 PMID: 40875536

10

COVID-19 Immunologic Antiviral Therapy With Omalizumab (CIAO)—a Randomized Controlled Clinical Trial

Le M, Khoury L, Lu Y, Prosty C, Cormier M, Cheng MP, Fowler R, Murthy S, Tsang JLY, Ben-Shoshan M

Open Forum Infectious Diseases20243 citations

DOI: 10.1093/ofid/ofae102

Building Capacity in Innovative Adaptive Trial Designs for HIV and STBBI Research: The CTN-Québec Training Platform

Principal investigatorCIHR2025HIV/AIDS & STBBI Clinical Trials Research Network - Phase 2

Principal investigators: Durand, Madeleine; Beaudry, Sylvain; Fontaine, Guillaume; Gilbert, Caroline; Golchi, Shirin; Greenstreet, Peter J; Hedrich, Tanguy; Lebouché, Bertrand; Lessard, David; Vicente, Sergio

Keywords: Adaptive Trials; Hiv; Implementation Science; Stbbi; Training

$800,000

Randomized Double-Blind Placebo-Controlled Clinical Trial to Assess the Efficacy of Mycophenolate Mofetil in Subclinical Interstitial Lung Disease Associated with Systemic Sclerosis: a Feasibility Study

Co-investigatorCIHR2022Project Grant

Principal investigators: Hoa, Sabrina A

Keywords: Immunosuppressive Drugs; Interstitial Lung Disease; Systemic Sclerosis (Scleroderma)

$346,640

PRevention of COVID-19 with high dose Oral Vitamin D supplemental Therapy in Essential healthCare Teams (PROTECT)

Co-investigatorCIHR2020Operating Grant: COVID-19 Rapid Research Funding Opportunity - Therapeutics

Principal investigators: Ducharme, Francine M; Tremblay, Cécile L

Keywords: Disease Severity; Duration; Health Care Workers; Infection; Polymerase Chain Reaction; Sars-Cov-2; Serology; Unemployment; Work Absenteeism

$4,224,996

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Anna Heath and Anna Heath: 73 shared papers
Moshe Ben-Shoshan and Elena Netchiporouk: 49 shared papers
Ada Tang and Kevin Moncion: 47 shared papers
Elham Rahme and Elena Netchiporouk: 39 shared papers
Robert Fowler and Srinivas Murthy: 16 shared papers
Shirin Golchi and Shirin Golchi: 16 shared papers
Jennifer Tsang and Robert Fowler: 14 shared papers
Jennifer Tsang and Srinivas Murthy: 13 shared papers
Ada Tang and Alexander Thiel: 9 shared papers
Kevin Moncion and Alexander Thiel: 6 shared papers
Elham Rahme and Moshe Ben-Shoshan: 6 shared papers
Claudine Gauthier and Claudine Gauthier: 6 shared papers
Ada Tang and Baraa Al-Khazraji: 5 shared papers
Baraa Al-Khazraji and Kevin Moncion: 5 shared papers
Robert Fowler and Ivy Cheng: 4 shared papers
Anna Heath and Eleanor Pullenayegum: 4 shared papers
Karl Looper and David Benrimoh: 3 shared papers
Srinivas Murthy and Shirin Golchi: 3 shared papers
Srinivas Murthy and Shirin Golchi: 3 shared papers
Anna Heath and Eleanor Pullenayegum: 3 shared papers
Jennifer Tsang and Elham Rahme: 2 shared papers
Jennifer Tsang and Nandini Dendukuri: 2 shared papers
Jennifer Tsang and Moshe Ben-Shoshan: 2 shared papers
Jennifer Tsang and Elena Netchiporouk: 2 shared papers
Jennifer Tsang and Shirin Golchi: 2 shared papers
Jennifer Tsang and Shirin Golchi: 2 shared papers
Robert Fowler and Nandini Dendukuri: 2 shared papers
Robert Fowler and Hubert Wong: 2 shared papers
Robert Fowler and Shirin Golchi: 2 shared papers
Elham Rahme and Nandini Dendukuri: 2 shared papers
Elham Rahme and Shirin Golchi: 2 shared papers
Nandini Dendukuri and Shirin Golchi: 2 shared papers
Nandini Dendukuri and Caroline Quach: 2 shared papers
Moshe Ben-Shoshan and Shirin Golchi: 2 shared papers
Elena Netchiporouk and Shirin Golchi: 2 shared papers
Cristina Longo and Caroline Quach: 2 shared papers
Ada Tang and Christopher Rowley: 1 shared paper
Ada Tang and Claudine Gauthier: 1 shared paper
Ada Tang and Claudine Gauthier: 1 shared paper
Ada Tang and Shirin Golchi: 1 shared paper
Baraa Al-Khazraji and Christopher Rowley: 1 shared paper
Baraa Al-Khazraji and Alexander Thiel: 1 shared paper
Baraa Al-Khazraji and Claudine Gauthier: 1 shared paper
Baraa Al-Khazraji and Claudine Gauthier: 1 shared paper
Baraa Al-Khazraji and Shirin Golchi: 1 shared paper
Christopher Rowley and Kevin Moncion: 1 shared paper
Christopher Rowley and Shirin Golchi: 1 shared paper
Kevin Moncion and Shirin Golchi: 1 shared paper
Alexander Thiel and Shirin Golchi: 1 shared paper
Karl Looper and Shirin Golchi: 1 shared paper
Karl Looper and Shirin Golchi: 1 shared paper
Srinivas Murthy and Anna Heath: 1 shared paper
Srinivas Murthy and Ivy Cheng: 1 shared paper
Srinivas Murthy and Anna Heath: 1 shared paper
Hubert Wong and Anna Heath: 1 shared paper
Hubert Wong and Shirin Golchi: 1 shared paper
Hubert Wong and Shirin Golchi: 1 shared paper
Anna Heath and Shirin Golchi: 1 shared paper
Claudine Gauthier and Shirin Golchi: 1 shared paper
Shirin Golchi and Ivy Cheng: 1 shared paper
Shirin Golchi and Cristina Longo: 1 shared paper
Shirin Golchi and David Benrimoh: 1 shared paper
Shirin Golchi and Eleanor Pullenayegum: 1 shared paper
Shirin Golchi and Caroline Quach: 1 shared paper
Ivy Cheng and Shirin Golchi: 1 shared paper
Claudine Gauthier and Shirin Golchi: 1 shared paper
Cristina Longo and Shirin Golchi: 1 shared paper
David Benrimoh and Shirin Golchi: 1 shared paper
Shirin Golchi and Anna Heath: 1 shared paper
Shirin Golchi and Eleanor Pullenayegum: 1 shared paper
Shirin Golchi and Caroline Quach: 1 shared paper

Medicine
Rehabilitation Science
Biostatistics Division
Médecine interne
Infectious Diseases
Dermatology
Allergy and Clinical Immunology
Other

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Adaptive Trials Dear Professor Golchi, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Protecting the brain from post-stroke cognitive impairment and dementia with multimodal exercise training: study protocol for a Bayesian adaptive trial (PROTECT)" (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Building Capacity in Innovative Adaptive Trial Designs for HIV and STBBI Research: The CTN-Québec Training Platform" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]