Valérie Mongrain, Université de Montréal

Research

Electroencephalography Gene Expression Plasticity Biological Rhythms Brain Oscillations Circadien Timing System Immune System Insects And Unicellular Organisms

Latest papers

Fxr1 regulates sleep and synaptic homeostasis.
The EMBO journal · 2020
Rapid fast-delta decay following prolonged wakefulness marks a phase of wake-inertia in NREM sleep.
Nature communications · 2020
DNA methylation and transcription onset in the brain.
Epigenomics · 2017

All 4 publications

Latest funding

An integrated approach to evaluate and modulate neuronal activity
NSERC · 2024 · Co-investigator
$150,000
Chronobiology: from the Cell to Medicine and Society (Chronobiologie : de la cellule à la médecine et la société)
CIHR · 2024 · Nominated PI
$10,000
Defining interrelationships between brain region-specific structural plasticity and sleep electrophysiology via the integration of sex and learning
CIHR · 2021 · Nominated PI
$925,650

All 14 grants and awards

4 publications.

01

Fxr1 regulates sleep and synaptic homeostasis.

Khlghatyan J, Evstratova A, Bozoyan L, Chamberland S, Chatterjee D, Marakhovskaia A, Soares Silva T, Toth K, Mongrain V, Beaulieu JM

The EMBO journal2020

DOI: 10.15252/embj.2019103864 PMID: 32893934

02

Rapid fast-delta decay following prolonged wakefulness marks a phase of wake-inertia in NREM sleep.

Hubbard J, Gent TC, Hoekstra MMB, Emmenegger Y, Mongrain V, Landolt HP, Adamantidis AR, Franken P

Nature communications2020

DOI: 10.1038/s41467-020-16915-0 PMID: 32561733

03

DNA methylation and transcription onset in the brain.

Massart R, Suderman M, Mongrain V, Szyf M

Epigenomics2017

DOI: 10.2217/epi-2016-0184 PMID: 28517952

04

An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks.

Bedont JL, LeGates TA, Buhr E, Bathini A, Ling JP, Bell B, Wu MN, Wong PC, Van Gelder RN, Mongrain V, Hattar S, Blackshaw S

Current biology : CB2017

DOI: 10.1016/j.cub.2016.11.008 PMID: 28017605

An integrated approach to evaluate and modulate neuronal activity

Co-investigatorNSERC2024Research Tools and Instruments

Principal investigators: Vande Velde, Christine

Keywords: electrophysiology; mouse models; neurometabolism; neuronal activity; neurons; neurotransmission; RNA binding proteins; stereotaxic injections

$150,000

Chronobiology: from the Cell to Medicine and Society (Chronobiologie : de la cellule à la médecine et la société)

Nominated PICIHR2024Planning and Dissemination Grant - Institute Community Support

Principal investigators: Mongrain, Valérie

Keywords: Biological Rhythms; Brain Oscillations; Circadien Timing System; Immune System; Insects And Unicellular Organisms; Mental Health; Neurology And Psychiatry; Physiology; Shift-Work; Sleep

$10,000

Defining interrelationships between brain region-specific structural plasticity and sleep electrophysiology via the integration of sex and learning

Nominated PICIHR2021Project Grant

Principal investigators: Mongrain, Valérie

Keywords: Adhesion Molecules; Camp Signaling; Cerebral Cortex; Cofilin; Electroencephalography; Hippocampus; Sex Differences; Slow Wave And Paradoxical Sleep; Spatial And Motor Learning; Spine Morphology

$925,650

Mechanisms underlying the roles of cell adhesion molecules in the circadian timing system

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Mongrain, Valérie

$290,000

Canada Research Chair - Tier 2

Nominated PICIHR2020Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Mongrain, Valérie

Keywords: Crc

$500,000

The impact of amyloid-induced neurodegeneration on sleep features and memory processes

Co-investigatorCIHR2020Project Grant

Principal investigators: Brouillette, Jonathan

Keywords: Aging; Alzheimer'S Disease; Amyloid-Beta Oligomers; Animal Model; Molecular And Cellular Biology; Neurodegeneration; Sleep

$619,650

Investigating the role of Ephrins and Eph receptors in circadian physiology

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Mongrain, Valérie

$285,000

Canada Research Chair Tier 2

Nominated PICIHR2015Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Mongrain, Valérie

Keywords: C

$500,000

Role of Neuroligin 1 in Sleep Homeostasis

Nominated PICIHR2014CIHR New Investigator

Principal investigators: Mongrain, Valérie

Keywords: Clock Genes; Electroencephalography; Gene Expression; Plasticity; Protein Level; Sleep Homeostasis; Synaptic Adhesion Molecules; Traumatic Brain Injury

$300,000

Genetic modifiers of human sleep and polysomnography traits

Co-investigatorCIHR2013Operating Grant

Principal investigators: Warby, Simon

Keywords: Brain Activity; Brain Oscillations; Eeg; Genetics; Genome-Wide Association Study; Neurological Disease; Physiology; Polysomnography; Sleep; Sleep Disorders

$617,565

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Centre d'étude du sommeil
Cellular and Molecular Medicine
Pharmacology and Therapeutics

Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Katalin Toth

Cellular and Molecular Medicine

1 shared papers, latest 2020

Moshe Szyf

Pharmacology and Therapeutics

1 shared papers, latest 2017

Write to this professor

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Applying for

Paper to mentionMention their CIHR grant from 2024

Subject: Prospective PhD student: Electroencephalography Dear Professor Mongrain, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Fxr1 regulates sleep and synaptic homeostasis." (2020), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Chronobiology: from the Cell to Medicine and Society (Chronobiologie : de la cellule à la médecine et la société)" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]