David Cooper, University of Saskatchewan

Research

Aging Bone Osteoporosis Glucocorticoid Imaging In Vivo Ovariectomy Rabbit

Latest papers

The Effects of Circadian Period Misalignment on Odontogenesis.
Stem cells and development · 2026
Glucocorticoids disrupt longitudinal advance of cortical bone basic multicellular units in the rabbit distal tibia.
Bone · 2024 · senior author
Bone turnover and mineralisation kinetics control trabecular BMDD and apparent bone density: insights from a discrete statistical bone remodelling model.
Biomechanics and modeling in mechanobiology · 2024

All 10 publications

Latest funding

Advancing a conceptual model of the "Experience of Embodied Movement" construct
SSHRC · 2023 · Co-investigator
$107,144
Identifying the social determinants of lead poisoning in British colonial populations of the Caribbean
SSHRC · 2023 · Co-investigator
$128,064
High Efficiency X-ray Macroscope for Imaging of Musculoskeletal Development and Aging at the Canadian Light Source Synchrotron
NSERC · 2022 · Principal investigator
$150,000

All 26 grants and awards

10 publications.

01

The Effects of Circadian Period Misalignment on Odontogenesis.

Said R, Mortazavi H, Hoja I, Cooper D, Papagerakis S, Papagerakis P

Stem cells and development2026

DOI: 10.1177/15473287261466918 PMID: 42427205

02

Glucocorticoids disrupt longitudinal advance of cortical bone basic multicellular units in the rabbit distal tibia.

Harrison K, Loundagin L, Hiebert B, Panahifar A, Zhu N, Marchiori D, Arnason T, Swekla K, Pivonka P, Cooper D

Bone2024Senior author

DOI: 10.1016/j.bone.2024.117171 PMID: 38901788

03

Bone turnover and mineralisation kinetics control trabecular BMDD and apparent bone density: insights from a discrete statistical bone remodelling model.

Castoldi NM, Pickering E, Sansalone V, Cooper D, Pivonka P

Biomechanics and modeling in mechanobiology2024

DOI: 10.1007/s10237-023-01812-4 PMID: 38280951

04

Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice.

Said R, Mortazavi H, Cooper D, Ovens K, McQuillan I, Papagerakis S, Papagerakis P

Frontiers in physiology2023

DOI: 10.3389/fphys.2023.1100714 PMID: 36935757

05

Globular structure of the hypermineralized tissue in human femoral neck.

Wang Q, Tang T, Cooper D, Eltit F, Fratzl P, Guy P, Wang R

Journal of structural biology2020

DOI: 10.1016/j.jsb.2020.107606 PMID: 32905849

06

Does physical activity in adolescence have site-specific and sex-specific benefits on young adult bone size, content, and estimated strength?

Duckham RL, Baxter-Jones AD, Johnston JD, Vatanparast H, Cooper D, Kontulainen S

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2014

DOI: 10.1002/jbmr.2055 PMID: 23907819

07

Micro-CT image reconstruction based on alternating direction augmented Lagrangian method and total variation.

Gopi VP, Palanisamy P, Wahid KA, Babyn P, Cooper D

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society2013Senior author

DOI: 10.1016/j.compmedimag.2013.08.006 PMID: 24070671

08

Improved Compressed Sensing‐Based Algorithm for Sparse‐View CT Image Reconstruction

Zhu Z, Wahid K, Babyn P, Cooper D, Pratt I, Carter Y

Computational and Mathematical Methods in Medicine201371 citations

DOI: 10.1155/2013/185750

09

X-ray diffraction enhanced imaging as a novel method to visualize low-density scaffolds in soft tissue engineering.

Zhu N, Chapman D, Cooper D, Schreyer DJ, Chen X

Tissue engineering. Part C, Methods2011

DOI: 10.1089/ten.tec.2011.0102 PMID: 21870940

10

Brief communication: the relation between standard error of the estimate and sample size of histomorphometric aging methods.

Hennig C, Cooper D

American journal of physical anthropology2011Senior author

DOI: 10.1002/ajpa.21540 PMID: 21590752

Advancing a conceptual model of the "Experience of Embodied Movement" construct

Co-investigatorSSHRC2023Insight Grants

Principal investigators: Pila, Eva

Keywords: physical activity; gender equity; body image; embodiment

$107,144

Identifying the social determinants of lead poisoning in British colonial populations of the Caribbean

Co-investigatorSSHRC2023Insight Grants

Principal investigators: Varney, Tamara L.

Keywords: bioarchaeology; social determinants; bone; lead; synchrotron; x-ray fluorescence imaging; British Royal Naval history; Caribbean history

$128,064

High Efficiency X-ray Macroscope for Imaging of Musculoskeletal Development and Aging at the Canadian Light Source Synchrotron

Principal investigatorNSERC2022Research Tools and Instruments

Principal investigators: Cooper, David

$150,000

A comprehensive study on bone quality for the prediction of second hip fractures

Co-investigatorCIHR2021Project Grant

Principal investigators: Wang, Rizhi; Guy, Pierre

Keywords: Biomaterials; Biomechanics; Bone Biology; Bone Histology; Bone Mineralization; Bone Structure; Hip Fracture; Osteoporosis

$833,850

INSPIRE. Interdisciplinary Network for the Synchrotron: Promoting Innovation, Research, and Enrichment

Co-investigatorNSERC2021Collaborative Research and Training Experience

Principal investigators: Pickering, Ingrid

$1,062,690

Spatio-temporal regulation of cortical bone remodeling

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Cooper, David

$168,000

A Novel Platform for Investigating Osteoporosis Treatment: Integrating Four-Dimensional Synchrotron Imaging and Computational Modeling

Principal investigatorSSHRC2020New Frontiers in Research Fund - Exploration

Principal investigators: Cooper, David

$250,000

High-throughput X-ray micro-tomography station at the Canadian Light Source

Principal investigatorNSERC2018Research Tools and Instruments

Principal investigators: Cooper, David

$145,000

Longitudinal Imaging of Cortical Bone Remodeling Events in a Rabbit Model of Osteoporosis: A Novel Platform for the Study of Bone Physiology and Disease

Nominated PICIHR2017Catalyst Grant: Musculoskeletal Health and Arthritis

Principal investigators: Cooper, David M

Keywords: Aging; Bone; Glucocorticoid; Imaging; In Vivo; Osteoporosis; Ovariectomy; Rabbit; Remodeling; Synchrotron

$100,000

Saskatchewan Bone Strength Development Study (BSDS)

Co-investigatorCIHR2016Project Grant

Principal investigators: Kontulainen, Saija; Nour, Munier A

Keywords: Antecedents Of Osteoporosis; Bone; Children; Muscle; Nutrition; Physical Activity; Primary Prevention; Type 1 Diabetes

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Anatomy and Cell Biology
Mechanical Engineering
Other

Co-authors at University of Saskatchewan, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Pierre Guy

Mechanical Engineering

1 shared papers, latest 2020

Xiongbiao Chen

Anatomy and Cell Biology

1 shared papers, latest 2011

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2022

Subject: Prospective PhD student: Aging Dear Professor Cooper, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "The Effects of Circadian Period Misalignment on Odontogenesis." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "High Efficiency X-ray Macroscope for Imaging of Musculoskeletal Development and Aging at the Canadian Light Source Synchrotron" (2022), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

David Cooper

Research

Latest papers

Latest funding

The Effects of Circadian Period Misalignment on Odontogenesis.

Glucocorticoids disrupt longitudinal advance of cortical bone basic multicellular units in the rabbit distal tibia.

Bone turnover and mineralisation kinetics control trabecular BMDD and apparent bone density: insights from a discrete statistical bone remodelling model.

Deciphering the functions of Stromal Interaction Molecule-1 in amelogenesis using AmelX-iCre mice.

Globular structure of the hypermineralized tissue in human femoral neck.

Does physical activity in adolescence have site-specific and sex-specific benefits on young adult bone size, content, and estimated strength?

Micro-CT image reconstruction based on alternating direction augmented Lagrangian method and total variation.

Improved Compressed Sensing‐Based Algorithm for Sparse‐View CT Image Reconstruction

X-ray diffraction enhanced imaging as a novel method to visualize low-density scaffolds in soft tissue engineering.

Brief communication: the relation between standard error of the estimate and sample size of histomorphometric aging methods.

Advancing a conceptual model of the "Experience of Embodied Movement" construct

Identifying the social determinants of lead poisoning in British colonial populations of the Caribbean

High Efficiency X-ray Macroscope for Imaging of Musculoskeletal Development and Aging at the Canadian Light Source Synchrotron

A comprehensive study on bone quality for the prediction of second hip fractures

INSPIRE. Interdisciplinary Network for the Synchrotron: Promoting Innovation, Research, and Enrichment

Spatio-temporal regulation of cortical bone remodeling

A Novel Platform for Investigating Osteoporosis Treatment: Integrating Four-Dimensional Synchrotron Imaging and Computational Modeling

High-throughput X-ray micro-tomography station at the Canadian Light Source

Longitudinal Imaging of Cortical Bone Remodeling Events in a Rabbit Model of Osteoporosis: A Novel Platform for the Study of Bone Physiology and Disease

Saskatchewan Bone Strength Development Study (BSDS)

Frequent collaborators

Paul Babyn

Pierre Guy

Rizhi Wang

Hassanali Vatanparast

Saija Kontulainen

Isaac Pratt

Xiongbiao Chen