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Research
Latest papers
Dicer deficiency affects microglial function during demyelination and impairs remyelination.
Neurobiology of disease · 2025
Bipotential B-neutrophil progenitors are present in human and mouse bone marrow and emerge in the periphery upon stress hematopoiesis.
mBio · 2024
Micro-diffusely abnormal white matter: An early multiple sclerosis lesion phase with intensified myelin blistering.
Annals of clinical and translational neurology · 2024
Latest funding
- $1,361,700
Interferon responsive microglia regulate remyelination
CIHR · 2025 · Nominated PI
- $1,350,225
Aging impairs microglial phagocytosis and stalls remyelination
CIHR · 2023 · Nominated PI
- $1,097,775
Understanding CD33 as a Genetic Susceptibility Factor in Alzheimer's Disease
CIHR · 2023 · Co-investigator
3 publications.
Dicer deficiency affects microglial function during demyelination and impairs remyelination.
Tripathi A, Rai NK, Perles A, Courtney H, Jones C, Sapra A, Plemel J, Dutta R
Bipotential B-neutrophil progenitors are present in human and mouse bone marrow and emerge in the periphery upon stress hematopoiesis.
Shahbaz S, Rosero EP, Syed H, Hnatiuk M, Bozorgmehr N, Rahmati A, Zia S, Plemel J, Osman M, Elahi S
Micro-diffusely abnormal white matter: An early multiple sclerosis lesion phase with intensified myelin blistering.
Luchicchi A, Muñoz-Gonzalez G, Halperin ST, Strijbis E, van Dijk LHM, Foutiadou C, Uriac F, Bouman PM, Schouten MAN, Plemel J, 't Hart BA, Geurts JJG, Schenk GJ
Interferon responsive microglia regulate remyelination
Principal investigators: Plemel, Jason R; Giuliani, Fabrizio; Schenk, Geert
Keywords: Interferon; Microglia; Multiple Sclerosis; Remyelination
Aging impairs microglial phagocytosis and stalls remyelination
Principal investigators: Plemel, Jason R
Keywords: Age; Microglia; Phagocytosis; Remyelination; Single Cell Rna Sequencing
Understanding CD33 as a Genetic Susceptibility Factor in Alzheimer's Disease
Principal investigators: Macauley, Matthew S
Keywords: Alzheimer'S Disease; Amyloid; Cd33; Microglia; Neurodegeneration; Siglec; Splicing; Trem2
Deciphering macrophage phenotypes in neuropathic pain
Principal investigators: Kerr, Bradley
Keywords: Cytokines; Drg; Macrophage; Nerve Injury; Neuroma; Pain; Single Cell Sequencing; Single Nucleus Sequencing
Mechanisms of programming of cardiorenal dysfunction by perinatal iron deficiency
Principal investigators: Bourque, Stephane
Keywords: Developmental Origins Of Health And Disease; Iron Deficiency; Macrophages; Mitochondrial Function; Pregnancy; Reactive Oxygen Species; Renal Development
Understanding inflammation in the brain: integration of glycomics and viruses in multiple sclerosis
Principal investigators: Plemel, Jason
Keywords: Multiple sclerosis Virology Glycomics Clinical samples animal models single cell transcriptomics machine learning molecular arrays
Understanding inflammation in the brain: integration of glycomics and viruses in multiple sclerosis
Principal investigators: Plemel, Jason
Keywords: Multiple sclerosis; Virology; Glycomics; Clinical samples; animal models; single cell transcriptomics; machine learning; molecular arrays
Canada Research Chair - Tier 2
Principal investigators: Plemel, Jason R
Keywords: Crc
Cytokine involvement in microglia proliferation
Principal investigators: Plemel, Jason
Role of microglia during remyelination
Principal investigators: Plemel, Jason R
Keywords: Bioinformatics; Inflammation; Macrophage; Microglia; Multiple Sclerosis; Myelin; Remyelination; Single Cell Rna Sequencing; Tissue Biomarkers; White Matter Injury
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine/Neurology
- Medicine
- Dentistry
- Mike Petryk School of Dentistry
Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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