This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.
Research
Latest papers
De novo phosphatidylcholine synthesis in the small intestinal epithelium is required for normal dietary lipid handling and maintenance of the mucosal barrier.
Biochimica et biophysica acta. Molecular and cell biology of lipids · 2022
β-Cell Knockout of SENP1 Reduces Responses to Incretins and Worsens Oral Glucose Tolerance in High-Fat Diet-Fed Mice.
Diabetes · 2021
Transient antibiotic-induced changes in the neonatal swine intestinal microbiota impact islet expression profiles reducing subsequent function.
American journal of physiology. Regulatory, integrative and comparative physiology · 2021
Latest funding
- $160,000
Non-receptor tyrosine kinases in beta-cells
NSERC · 2019 · Principal investigator
- $860,625
Role of the non-receptor tyrosine kinase Lyn in the regulation of pancreatic beta-cell mass and function
CIHR · 2018 · Nominated PI
- $656,307
Role of SirT1 in the regulation of pancreatic beta-cell mass and function
CIHR · 2013 · Nominated PI
11 publications.
De novo phosphatidylcholine synthesis in the small intestinal epithelium is required for normal dietary lipid handling and maintenance of the mucosal barrier.
Carlin S, Kennelly JP, Fedoruk H, Quiroga A, Leonard KA, Nelson R, Thiesen A, Buteau J, Lehner R, Jacobs R
β-Cell Knockout of SENP1 Reduces Responses to Incretins and Worsens Oral Glucose Tolerance in High-Fat Diet-Fed Mice.
Lin H, Smith N, Spigelman AF, Suzuki K, Ferdaoussi M, Alghamdi TA, Lewandowski SL, Jin Y, Bautista A, Wang YW, Manning Fox JE, Merrins MJ, Buteau J, MacDonald PE
Transient antibiotic-induced changes in the neonatal swine intestinal microbiota impact islet expression profiles reducing subsequent function.
Sosa Alvarado C, Yang K, Qiu H, Mills E, Fouhse JM, Ju T, Buteau J, Field CJ, Willing BP, Chan CB
Intestinal Phospholipid Disequilibrium Initiates an ER Stress Response That Drives Goblet Cell Necroptosis and Spontaneous Colitis in Mice.
Kennelly JP, Carlin S, Ju T, van der Veen JN, Nelson RC, Buteau J, Thiesen A, Richard C, Willing BP, Jacobs RL
Disruption of Beta-Cell Mitochondrial Networks by the Orphan Nuclear Receptor Nor1/Nr4a3.
Close AF, Dadheech N, Lemieux H, Wang Q, Buteau J
The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass.
Close AF, Dadheech N, Villela BS, Rouillard C, Buteau J
Intestinal de novo phosphatidylcholine synthesis is required for dietary lipid absorption and metabolic homeostasis.
Kennelly JP, van der Veen JN, Nelson RC, Leonard KA, Havinga R, Buteau J, Kuipers F, Jacobs RL
Insulin decreases expression of the proinflammatory receptor proteinase-activated receptor-2 on human airway epithelial cells.
Gandhi VD, Shrestha Palikhe N, Hamza SM, Dyck JRB, Buteau J, Vliagoftis H
Evidence of unrestrained beta-cell proliferation and neogenesis in a patient with hyperinsulinemic hypoglycemia after gastric bypass surgery.
Dadheech N, Garrel D, Buteau J
HSF1 acetylation decreases its transcriptional activity and enhances glucolipotoxicity-induced apoptosis in rat and human beta cells.
Purwana I, Liu JJ, Portha B, Buteau J
Non-receptor tyrosine kinases in beta-cells
Principal investigators: Buteau, Jean
Role of the non-receptor tyrosine kinase Lyn in the regulation of pancreatic beta-cell mass and function
Principal investigators: Buteau, Jean
Keywords: Apoptosis; Beta-Cell; Cell Signalling; Diabetes; Kinase; Proliferation; Signal Transduction
Role of SirT1 in the regulation of pancreatic beta-cell mass and function
Principal investigators: Buteau, Jean
Keywords: Animal Models; Apoptosis; Diabetes; Gene Expression; Insulin Secretion; Metabolism; Pancreatic Beta-Cells; Proliferation; Transcription Factors
Glucagon-Like Peptide-1 and pancreatic beta-cell neogenesis
Principal investigators: Buteau, Jean
Keywords: Beta-Cell; Diabetes; Differentiation; Growth Factor; Insulin; Lineage Tracing; Pancreas; Signal Transduction; Transcription Factors
Glucagon-like peptide-1 and pancreatic beta-cell neogenesis
Principal investigators: Buteau, Jean
Keywords: Diabetes; Differentiation; Growth Factor; Pancreatic Beta-Cell; Proliferation; Signal Transduction
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Richard Lehner and Jean Buteau: 1 shared paper
- Jean Buteau and Harissios Vliagoftis: 1 shared paper
- Jean Buteau and Caroline Richard: 1 shared paper
- Human Nutrition
- Agricultural, Food and Nutritional Science
- Medicine
- Pediatrics
Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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