This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Effects of music on hepatic cytochrome P450 1A enzymes in Sprague Dawley rats.
Toxicology and applied pharmacology · 2026
Potential role of lipophagy impairment for anticancer effects of glycolysis-suppressed pancreatic ductal adenocarcinoma cells.
Cell death discovery · 2024
STAT3 but Not HIF-1α Is Important in Mediating Hypoxia-Induced Chemoresistance in MDA-MB-231, a Triple Negative Breast Cancer Cell Line.
Cancers · 2017
Latest funding
- $1,032,750
Targeting Soluble Epoxide Hydrolase to Modulate Cardiomyocyte Senescence
CIHR · 2026 · Nominated PI
- $906,526
Synthetic analogues based on metabolites of omega-3 fatty acids protect mitochondria in aging hearts
CIHR · 2023 · Nominated PI
- $1,090,125
Aging & Metabolic Flexibility
CIHR · 2022 · Co-investigator
5 publications.
Effects of music on hepatic cytochrome P450 1A enzymes in Sprague Dawley rats.
Shalaby AH, Adhiya J, Al-Dajani AR, El-Mahrouk SR, Olympus C, Seubert J, Ahonen H, El-Kadi AOS, Kiang TKL
Potential role of lipophagy impairment for anticancer effects of glycolysis-suppressed pancreatic ductal adenocarcinoma cells.
Zhang Z, Aoki H, Umezawa K, Kranrod J, Miyazaki N, Oshima T, Hirao T, Miura Y, Seubert J, Ito K, Aoki S
STAT3 but Not HIF-1α Is Important in Mediating Hypoxia-Induced Chemoresistance in MDA-MB-231, a Triple Negative Breast Cancer Cell Line.
Soleymani Abyaneh H, Gupta N, Radziwon-Balicka A, Jurasz P, Seubert J, Lai R, Lavasanifar A
Pharmacologic protein kinase Cα inhibition uncouples human platelet-stimulated angiogenesis from collagen-induced aggregation.
Moncada de la Rosa C, Radziwon-Balicka A, El-Sikhry H, Seubert J, Ruvolo PP, Radomski MW, Jurasz P
Inhibition of malonyl-CoA decarboxylase reduces the inflammatory response associated with insulin resistance.
Samokhvalov V, Ussher JR, Fillmore N, Armstrong IK, Keung W, Moroz D, Lopaschuk DG, Seubert J, Lopaschuk GD
Targeting Soluble Epoxide Hydrolase to Modulate Cardiomyocyte Senescence
Principal investigators: Seubert, John M
Keywords: Aging; Cardiomyocyte; Heart; Mitochondria; Senescence; Soluble Epoxide Hydrolase
Synthetic analogues based on metabolites of omega-3 fatty acids protect mitochondria in aging hearts
Principal investigators: Seubert, John M
Keywords: Aging; Cytochrome P450; Drug Development; Mitochondria; Omega-3 Pufa; Soluble Epoxide Hydrolase; Synthetic Compounds
Aging & Metabolic Flexibility
Principal investigators: Ussher, John R
Keywords: Aging; Metabolic Flexibility; Mitochondria; Muscle Function; Pyruvate Dehydrogenase
Synthetic analogues based on metabolites of omega-3 fatty acids protect mitochondria
Principal investigators: Seubert, John M
Keywords: Aging; Cytochrome P450; Drug Development; Mitochondria; Omega-3 Pufa; Soluble Epoxide Hydrolase; Synthetic Compounds
Investigating the differential effects of LPS toward cardiac mitochondria in young and aged mice
Principal investigators: Seubert, John
Improving Mitochondria in Aged Hearts Following Ischemic Injury with Novel Epoxy Lipids
Principal investigators: Seubert, John M
Keywords: Aging; Cardiac; Cytochome P450 Epoxygenases; Drug Development; Eicosanoids; Human Heart; Ischemia; Mitochondria; Omega-3 Pufa; Soluble Epoxide Hydolase
Investigating how the environmental toxicant LPS impacts mitochondrial quality control and the biological aging process in heart
Principal investigators: Seubert, John
Improving Mitochondria in Aged Hearts Following Ischemia-Reperfusion Injury with Novel Epoxy Lipids
Principal investigators: Seubert, John M
Keywords: Ageing; Cardiac; Cytochrome P450 Epoxygenases; Drug Development; Eicosanoids; Human Explanted Heart; Ischemia/Reperfusion Injury; Mitochondria; Omega-3 Pufa; Soluble Epoxide Hydrolase
Nanodelivery Systems for Modulation of Chemotherapy Response in Invasive and Metastatic Breast Cancer
Principal investigators: Lavasanifar, Afsaneh
Keywords: Cancer Chemotherapy; Drug Delivery; Drug Resistance; Nanotechnology; Sirna Delivery; Targeted Therapy
Cytochrome P450 Derived Metabolites of Arachidonic Acid Differentially Regulate Cell Death Pathways
Principal investigators: Seubert, John
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
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