Faculty profile

Karen Madsen

ResearcherMedicineUniversity of Alberta

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.

Karen Madsen

Researcher

Medicine

Health Sciences

University of Alberta

Edmonton, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
10 publications in the last five years, latest in 2026.
Principal investigator on 4 research grants (4 CIHR), most recently in 2016.
Supervisor on 4 trainee awards (4 CIHR), most recently in 2019.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

963

Citations

169

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Crohn'S Disease Fecal Transplants Microbiome Gut Microbiome Immune Development Inflammatory Bowel Disease Western Diet

Latest papers

Gut microbiome in surgical oncology: mechanisms, perioperative outcomes, and therapeutic opportunities.
The British journal of surgery · 2026
Mast cell-derived IL-13 as a driver of Crohn disease-associated intestinal fibrosis.
Inflammatory bowel diseases · 2026
Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease
Gastroenterology · 2025

All 51 publications

Latest funding

Intracellular uropathogenic bacteria biofilm-like aggregates: A new paradigm in the pathophysiology of urinary tract infections
SSHRC · 2022 · Co-investigator
$121,250
Fecal microbial transplantation and fiber supplementation in subjects with obesity and metabolic syndrome: a randomized, placebo-controlled, double blinded trial
CIHR · 2019 · Supervisor
$105,000
Fecal microbial transplantation in the management of patients with mild-to-moderate Crohn's disease
CIHR · 2016 · Nominated PI
$638,356

All 9 grants and awards

51 publications.

Gut microbiome in surgical oncology: mechanisms, perioperative outcomes, and therapeutic opportunities.

Dang J, Lee Y, Wills MV, Brown JM, Madsen K, Mocanu V

The British journal of surgery2026

DOI: 10.1093/bjs/znag082 PMID: 42370841

Mast cell-derived IL-13 as a driver of Crohn disease-associated intestinal fibrosis.

Safari K, Ma WJ, Sekhon P, Rai P, Menzies SC, Hoshino T, Fratzscher AS, Roth A, Madsen K, Sly LM

Inflammatory bowel diseases2026

DOI: 10.1093/ibd/izag127 PMID: 42418669

Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease

Lee S-H, Bushra M, Qiu L, Griffiths AM, Turpin W, Croitoru K, Lee S-H, Bushra M, Qiu L, Shao J

Gastroenterology202518 citations

DOI: 10.1053/j.gastro.2024.09.033

Correction: "Mouse mammary tumor virus is implicated in severity of colitis and dysbiosis in the IL-10-/- mouse model of inflammatory bowel disease".

Armstrong H, Rahbari M, Park H, Sharon D, Thiesen A, Hotte N, Sun N, Syed H, Abofayed H, Wang W, Madsen K, Wine E, Mason A

Microbiome2024

DOI: 10.1186/s40168-024-01850-9 PMID: 38907319

2023 Canadian Surgery Forum

Brière R, Habashi R, Merchant S, Cadili L, Alhumoud Z, Lau R, Gawad N, Valji R, Balmes PN, Tan JGK

Canadian Journal of Surgery20231 citationsOpen Access

DOI: 10.1503/cjs.014223 PMID: W4389488805

The Need for Fiber Addition in Symptomatic Heart Failure (FEAST-HF): A Randomized Controlled Pilot Trial.

Colin-Ramirez E, Alemayehu W, McAlister FA, Howlett JG, Willing BP, Forgie A, Madsen K, Dyck JRB, Ezekowitz JA

CJC open2023

DOI: 10.1016/j.cjco.2023.07.005 PMID: 37876886

Mouse mammary tumor virus is implicated in severity of colitis and dysbiosis in the IL-10-/- mouse model of inflammatory bowel disease.

Armstrong H, Rahbari M, Park H, Sharon D, Thiesen A, Hotte N, Sun N, Syed H, Abofayed H, Wang W, Madsen K, Wine E, Mason A

Microbiome2023

DOI: 10.1186/s40168-023-01483-4 PMID: 36869359

Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice

De Palma G, Shimbori C, Reed DE, Yu Y, Rabbia V, Lu J, Jimenez-Vargas N, Sessenwein J, Lopez-Lopez C, Pigrau M

Science Translational Medicine2022155 citations

DOI: 10.1126/scitranslmed.abj1895

Post-neonatal Outcomes of Infants Born to Women with Active Trimester One Inflammatory Bowel Disease: A Pilot Study.

Wu RY, Tandon P, Ambrosio L, Dunsmore G, Hotte N, Dieleman LA, Elahi S, Madsen K, Huang V

Digestive diseases and sciences2022

DOI: 10.1007/s10620-022-07430-x PMID: 35201477

Exploring Patient Perspectives on a 12-Week Online, Stress Reduction Intervention in Inflammatory Bowel Disease.

Watt M, Peerani F, Madsen K, Siffledeen J, Kroeker K, Lim A, Tandon P, Hyde A

Crohn's & colitis 3602022

DOI: 10.1093/crocol/otac036 PMID: 36777414

Intracellular uropathogenic bacteria biofilm-like aggregates: A new paradigm in the pathophysiology of urinary tract infections

Co-investigatorSSHRC2022New Frontiers in Research Fund - Exploration

Principal investigators: Cervera, Carlos

Keywords: Intracellular bacteria; urinary tract infections; bacteriophages; microbiome; urothelial cells

$121,250

Fecal microbial transplantation and fiber supplementation in subjects with obesity and metabolic syndrome: a randomized, placebo-controlled, double blinded trial

SupervisorCIHR2019Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Mocanu, Valentin

Keywords: Diabetes; Fecal Transplant; Fiber; Metabolic Syndrome; Metbolomics; Microbiome; Obesity

$105,000

Fecal microbial transplantation in the management of patients with mild-to-moderate Crohn's disease

Nominated PICIHR2016Project Grant

Principal investigators: Madsen, Karen L; Fedorak, Richard N; Kao, Dina H; Kaplan, Gilaad G; Kroeker, Karen I

Keywords: Crohn'S Disease; Fecal Transplants; Microbiome

$638,356

Role of western-style diet-induced changes in gut microbiota and immune function in the development of colitis

Nominated PICIHR2013Operating Grant

Principal investigators: Madsen, Karen L

Keywords: Gut Microbiome; Immune Development; Inflammatory Bowel Disease; Western Diet

$581,799

Role of Gene-Environmental Interactions in the Pathogenesis of Inflammatory Bowel Diseases

SupervisorCIHR2010Fellowship - Priority Announcement - Inflammatory Bowel Disease

Principal investigators: Salim, Saad Y

Keywords: Confocal Microscopy; Dendritic Cells; Flow Cytometry; Inflammatory Bowel Disease; Innate Immunity; Intestinal Permeability; Mucosal Immunology

$45,000

The role of the Intestinal Microbiome in Post-Operative Recurrence of Crohn's Ileocolitis

Nominated PICIHR2009Canadian Microbiome Initiative - LOI

Principal investigators: Madsen, Karen L; Fedorak, Richard N; Vogel, Hans (Harm) J

Keywords: Inflammatory Bowel Disease; Metabolomics; Metagenomics

Effects of bacterial DNA on innate and adaptive immune responses during intestinal inflammation

SupervisorCIHR2009Fellowship - Priority Announcement - Inflammatory Bowel Disease

Principal investigators: Albert, Eric J

Keywords: Adaptive Immunity; Bacterial Dna; Colitis; Gastroenterology; Inflammation; Inflammatory Bowel Disease; Innate Immunity; Probiotics; T Cells; Toll-Like Receptor 9

$45,000

The role of probiotics in modulating the barrier function of the gut epithelium

Nominated PICIHR2008Operating Grant

Principal investigators: Madsen, Karen L

Keywords: Crohn'S Disease; Inflammatory Bowel Disease; Innate Immunity; Microflora; Probiotics

$630,992

The role of small intestinal permeability in the pathogenesis of colitis.

SupervisorCIHR2008Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Arrieta Mendez, Marie-Claire

Keywords: Colitis; Flow Cytometry; Intestinal Permeability; Ion Exchange Chromatography; Mucosal Immunology; Oral Tolerance; T Cell Proliferation; Ussing Chambers

$70,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Karen Madsen

Research

Latest papers

Latest funding

Gut microbiome in surgical oncology: mechanisms, perioperative outcomes, and therapeutic opportunities.

Mast cell-derived IL-13 as a driver of Crohn disease-associated intestinal fibrosis.

Early Life Exposure to Parental Crohn’s Disease Is Associated With Offspring’s Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn’s Disease

Correction: "Mouse mammary tumor virus is implicated in severity of colitis and dysbiosis in the IL-10-/- mouse model of inflammatory bowel disease".

2023 Canadian Surgery Forum

The Need for Fiber Addition in Symptomatic Heart Failure (FEAST-HF): A Randomized Controlled Pilot Trial.

Mouse mammary tumor virus is implicated in severity of colitis and dysbiosis in the IL-10-/- mouse model of inflammatory bowel disease.

Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice

Post-neonatal Outcomes of Infants Born to Women with Active Trimester One Inflammatory Bowel Disease: A Pilot Study.

Exploring Patient Perspectives on a 12-Week Online, Stress Reduction Intervention in Inflammatory Bowel Disease.

Intracellular uropathogenic bacteria biofilm-like aggregates: A new paradigm in the pathophysiology of urinary tract infections

Frequent collaborators

Eytan Wine

Karen Madsen

Michael Laffin

Puneeta Tandon

Richard Fedorak

Wei Xu

Dina Kao

Remo Panaccione

Kenneth Croitoru

Heather Armstrong

Michael Surette

Andrew Mason

John Kenneth Marshall

David Mack

Osvaldo Espin Garcia

Alaa Rostom

Alain Bitton

Karen Kroeker

Heather Armstrong

Giada De Palma

Premysl Bercik

Paul Moayyedi

Thomas Walters

Paul Beck

Lawrence Paszat

Kednapa Thavorn

Gilaad Kaplan

Dean Fergusson

Stephen Michael Collins

Cagla Eskicioglu

Bradley Allan Petrisor

Elena Verdu

Timothy Whelan

Edward Passos

Maria Pinto-Sanchez

John Agzarian

Paul Engels

Ilun Yang

Dennis Hong

Bobby Shayegan