Faculty profile

Karina Top

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ProfessorPediatrics DeptUniversity of Alberta

Karina Top

Professor

Pediatrics Dept

Faculty of Medicine & Dentistry

University of Alberta

Edmonton, Alberta, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
84 publications in the last five years, latest in 2026.
Senior (last) author on 14 recent papers, a sign of leading a research group.
Principal investigator on 7 research grants (7 CIHR), most recently in 2024.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

159

Publications

2,452

Citations

192

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Alberta profile.

Adverse Events Following Immunization Immunogenicity Population-Based Methodology Rapid Response Research Capacity Vaccine Coverage Vaccine Hesitancy Vaccine Safety Vaccine Effectiveness

Latest papers

Safety and efficacy of mRNA vaccines: a mechanistic and public health perspective.
Lancet (London, England) · 2026
Revaccination of individuals with cardiac adverse events following COVID-19 vaccination: A Canadian Immunization Research Network study
Vaccine · 2026 · senior author
Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study
Human Vaccines & Immunotherapeutics · 2026

All 159 publications

Latest funding

Equity-Informed Evaluation of Expanding Hospital-Based Childhood Vaccination Services
CIHR · 2026 · Co-investigator
$665,552
POPCORN-RSV: A Canadian Pregnant Individual-Infant Trial for Respiratory Syncytial Virus Immunization
CIHR · 2026 · Co-investigator
$3,411,901
Canadian Immunization Research Network (CIRN) Renewal
CIHR · 2024 · Principal investigator

All 10 grants and awards

From the 150 most recent of 159 publications.

Safety and efficacy of mRNA vaccines: a mechanistic and public health perspective.

Blakney AK, Top KA, Cowling BJ, Larson HJ, Shattock RJ, Sadarangani M

Lancet (London, England)20263 citations

DOI: 10.1016/s0140-6736(26)00512-x PMID: 42379196

Revaccination of individuals with cardiac adverse events following COVID-19 vaccination: A Canadian Immunization Research Network study

Piché-Renaud P-P, Buchan CA, Burton C, Chapdelaine H, Jeewa A, Morris SK, Pernica JM, Pham-Huy A, Sadarangani M, Salvadori MI

Vaccine20263 citationsSenior authorOpen Access

DOI: 10.1016/j.vaccine.2025.128016

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Smolinski M, Chew JL, Constantinescu C, Buchan CA, Burton C, Carignan A, Castellucci LA, Suresh S, McConnell A, Morris SK

Human Vaccines & Immunotherapeutics20262 citationsOpen Access

DOI: 10.1080/21645515.2026.2644030

Strengthening Post-Market Vaccine Safety Surveillance Globally: An Interpretive Description Study from Kenya, South Africa, and Canada

Anila Naz AliSher, Shabnam Shaik, Nellie Myburgh, N. Ndaba, Alex Hinga, Winnie Okore, Samuel Sang, Salima Siraj, Thabisile Qwabi, Kimberley Gutu, Allan Matano, Antonia M. Di Castri, Sonali Kochhar, Eunice Wangeci Kagucia, Ziyaad Dangor, Clare Cutland, Karina A. Top, the International Network of Special Immunization Services (INSIS) Investigators

medRxiv20261 citationsOpen Access

DOI: 10.64898/2026.03.11.26347757

Outcomes and Multimorbidity among Children and Youth with Chronic Neurologic Disorders Hospitalized for COVID-19: A Canadian Immunization Monitoring Program, ACTive Study.

Farrar DS, Huang RS, Donner EJ, Bettinger JA, Campigotto AJ, Di Chiara C, Drouin O, Embree JE, Halperin SA, Jadavji T, Kazmi K, Moore Hepburn C, Papenburg J, Purewal R, Sadarangani M, Sauvé L, Top KA, Kakkar F, Morris SK, Canadian Immunization Monitoring Program, Active (IMPACT) Investigators

The Journal of pediatrics20261 citationsOpen Access

DOI: 10.1016/j.jpeds.2026.115012 PMID: 41620077

SARS-CoV-2 Coinfections and Severity in Hospitalized Children With Systematic Testing.

Di Chiara C, Farrar DS, Bettinger JA, Campigotto A, Drouin O, Embree J, Halperin SA, Jadavji T, Kazmi K, Papenburg J, Purewal R, Sadarangani M, Sauvé L, Top KA, Kakkar F, Morris SK, for Members of the Canadian Immunization Monitoring Program, Active (IMPACT) COVID-19 Study

The Pediatric infectious disease journal2026Open Access

DOI: 10.1097/inf.0000000000005396 PMID: 42717388

"I know how important it is": A qualitative analysis of participants' experiences in a vaccine safety study.

AliSher AN, Siraj S, Greyson D, Qwabi T, Ndaba N, Myburgh N, Top KA, International Network of Special Immunization Services (INSIS) Investigators

Human vaccines & immunotherapeutics2026Open Access

DOI: 10.1080/21645515.2026.2711466 PMID: 42605267

Immunogenicity and Safety of Live Attenuated Varicella Vaccine in Children and Youth With Solid Organ Transplants in Canada: A Canadian Immunization Research Network Study.

Burton C, Chew JL, Sadarangani M, Blydt-Hansen T, Gantt S, Morris SK, Suresh S, Pham-Huy A, Otley A, Tapiero B, Mitchell H, Cowan J, Sivro A, Piché-Renaud PP, Comeau JL, Top KA, Special Immunization Clinic Investigators

Pediatric transplantation2026Senior authorOpen Access

DOI: 10.1111/petr.70314 PMID: 41937257

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Michael Smolinski, Jo Lin Chew, Cora Constantinescu, C. Arianne Buchan, Catherine Burton, Alex Carignan, Lana A. Castellucci, Sneha Suresh, Athena McConnell, Shaun K. Morris, Monika Naus, Jeffrey M. Pernica, Anne Pham-Huy, Pierre-Philippe Piché-Renaud, Manish Sadarangani, Karina A. Top, Juthaporn Cowan

Figshare2026Open Access

DOI: 10.6084/m9.figshare.31803759

Three Doses and Six Months Later: Real-World SARS-CoV-2 Specific Humoral and Cell-Mediated Immunity in Children With Inborn Errors of Immunity.

Porto LLTN, Yazji D, Unninayar D, Decaluwe H, Derfalvi B, Palma A, Issekutz T, Kalashnikova T, Murguía-Favela L, Pham-Huy A, Rubin T, Suresh S, Upton J, Wright NAM, Chapdelaine H, Falcone EL, Top KA, Sadarangani M, Vinh DC, Barrett L, Oldford S, Langlois MA, Arnold C, Zhang T, Ramsay T, Cowan J, VISID study investigators

Journal of clinical immunology2026Open Access

DOI: 10.1007/s10875-026-02021-1 PMID: 42034835

Equity-Informed Evaluation of Expanding Hospital-Based Childhood Vaccination Services

Co-investigatorCIHR2026Project Grant

Principal investigators: MacDonald, Shannon E; Rafferty, Ellen

Keywords: Accessibility; Children & Youth; Health Equity; Healthcare Services; Immunization; Population Health; Vaccination; Vaccine Coverage; Vaccine Uptake

$665,552

POPCORN-RSV: A Canadian Pregnant Individual-Infant Trial for Respiratory Syncytial Virus Immunization

Co-investigatorCIHR2026Project Grant

Principal investigators: Morris, Shaun K; Boucoiran, Isabelle; Lavoie, Pascal; Li, Patricia T; Sadarangani, Manish; Sander, Beate H; Shapiro, Gilla

Keywords: Immunization; Infancy; Pregnancy; Respiratory Syncytial Virus

$3,411,901

Canadian Immunization Research Network (CIRN) Renewal

Principal investigatorCIHR2024Canadian Immunization Research Network - Full application

Principal investigators: Halperin, Scott A; Andrew, Melissa K; Bettinger, Julie A; Bolotin, Shelly; Brisson, Marc; Buchan, Sarah; Cowan, Juthaporn; Dubé, Eve; Greyson, Devon; Hatchette, Todd F; Heffernan, Jane M; Kwong, Jeffrey C; Langley, Joanne M; MacDonald, Shannon E; McNeil, Shelly A; Muller, Matthew P; Parsons Leigh, Jeanna J; Sadarangani, Manish; Top, Karina A

Keywords: Adverse Events Following Immunization; Immunogenicity; Population-Based Methodology; Rapid Response Research Capacity; Vaccine Coverage; Vaccine Effectiveness; Vaccine Hesitancy; Vaccine Modeling And Economic Analysis; Vaccine Safety; Vulnerable Populations

Pediatric Outcomes imProvement through COordination of Research Networks (POPCORN)

Principal investigatorCIHR2022Op. Grant: Canadian Pediatric COVID-19 Research Platform

Principal investigators: Quach-Thanh, Caroline; Galanis, Eleni; Strang, Robert A; Basta, Nicole; Bhatt, Maala; Buchanan, Francine; Burstein, Brett S; Carwana, Matthew; Choong, Karen; Constantin, Evelyn; Côté, Sylvana; Drouin, Olivier; Dugas, Marc-André; Fontela, Patricia S; Foo, Cheryl P; Foster, Jennifer; Freedman, Stephen B; Gagneur, Arnaud A; Gantt, Soren M; Gill, Peter J; Kakkar, Fatima; Kellner, James D; Klassen, Terry P; Lacaze-Masmonteil, Thierry; Lalgudi Ganesan, Saptharishi; Li, Patricia T; Mahant, Sanjay; Mater, Ahmed; Morris, Shaun K; Muttalib, Fiona; Papenburg, Jesse; Sadarangani, Manish; Sehgal, Anupam V; 't Jong, Geert W; Top, Karina A; Wahi, Gita; Wright, Bruce

Keywords: Child Health; Covid-19; Critical Care; Data Infrastructure; Emergency Department; Epidemiology; Inpatient Medicine; Vaccine Safety And Effectiveness

$6,700,000

Building capacity for systems biology analysis of adverse events following COVID-19 vaccination in low- and middle-income countries

Nominated PICIHR2021CIHR-CEPI Leadership Award for Vaccine Research

Principal investigators: Top, Karina A

Keywords: Covid-19; Immunization; Vaccination; Vaccine Safety

$199,706

Canadian Immunization Research Network: COVID-19 Vaccine Readiness

Principal investigatorCIHR2020Canadian Immunization Research Network: COVID-19 Vaccine Readiness Funding Opp

Principal investigators: Halperin, Scott A; Andrew, Melissa K; Bettinger, Julie A; Bolotin, Shelly; Brisson, Marc; De Serres, Gaston; De Wals, Philippe; Deeks, Shelley L; Dubé, Eve; Hatchette, Todd F; Kellner, James D; Kwong, Jeffrey C; Langley, Joanne M; Loeb, Mark B; MacDonald, Shannon E; McNeil, Shelly A; Top, Karina A; Ward, Brian J

Keywords: Adverse Events Following Immunization; Clinical Trials Capacity And Readiness; Immunogenicity; Knowledge Translation; Population-Based Methodology; Rapid Response Research Capacity; Vaccine Coverage; Vaccine Hesitancy; Vaccine Modeling; Vaccine Safety And Effectiveness

Canadian Immunization Research Network

Principal investigatorCIHR2017Canadian Immunization Research Network - Full application

Principal investigators: Halperin, Scott A; Andrew, Melissa K; Bettinger, Julie A; Bolotin, Shelly; Brisson, Marc; Burchell, Ann N; Coleman, Brenda L; Crowcroft, Natasha S; De Serres, Gaston; De Wals, Philippe; Deeks, Shelley L; Doroshenko, Alexander; Dubé, Eve; Gagneur, Arnaud A; Kwong, Jeffrey C; Langley, Joanne M; Loeb, Mark B; McNeil, Shelly A; Sadarangani, Manish; Top, Karina A; Ulanova, Marina; Ward, Brian J

$932,667

Health outcomes in children of mothers who received influenza vaccination during pregnancy

Co-investigatorCIHR2016Operating Grant: Analyses of Existing Cohorts & Databases - IHDCYH

Principal investigators: Fell, Deshayne B

Keywords: Immunization; Influenza; Maternal And Child Health; Population Health

$75,000

Canadian Immunization Research Network

Principal investigatorCIHR2014Canadian Immunization Research Network - Full application

Principal investigators: Halperin, Scott A; Andrew, Melissa K; Bettinger, Julie A; Bolotin, Shelly; Brisson, Marc; Coleman, Brenda L; Crowcroft, Natasha S; De Serres, Gaston; De Wals, Philippe; Deeks, Shelley L; Dubé, Eve; Fisman, David N; Hatchette, Todd F; Isenor, Jennifer; Kwong, Jeffrey C; Langley, Joanne M; Loeb, Mark B; MacDougall, Heather A; Mahmud, Salaheddin; McNeil, Shelly A; Naus, Monika; Ogilvie, Gina S; Quach-Thanh, Caroline; Scheifele, David W; Top, Karina A; Van Buynder, Paul; Vaudry, Wendy L; Ward, Brian J; Watts, Tania H; Wilson, Kumanan; Wilson, Sarah

$583,497

Canadian Immunization Research Network

Principal investigatorCIHR2013Canadian Immunization Research Network - LOI

Principal investigators: Halperin, Scott A; Andrew, Melissa K; Bettinger, Julie A; Bolotin, Shelly; Brisson, Marc; Coleman, Brenda L; Crowcroft, Natasha S; De Serres, Gaston; De Wals, Philippe; Deeks, Shelley L; Dubé, Eve; Hatchette, Todd F; Kwong, Jeffrey C; Langley, Joanne M; Loeb, Mark B; Mahmud, Salaheddin; McNeil, Shelly A; Naus, Monika; Quach-Thanh, Caroline; Scheifele, David W; Skowronski, Danuta Maria; Top, Karina A; Vaudry, Wendy L; Ward, Brian J; Watts, Tania H; Wilson, Kumanan; Wilson, Sarah

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Karina Top

Research

Latest papers

Latest funding

Safety and efficacy of mRNA vaccines: a mechanistic and public health perspective.

Revaccination of individuals with cardiac adverse events following COVID-19 vaccination: A Canadian Immunization Research Network study

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Strengthening Post-Market Vaccine Safety Surveillance Globally: An Interpretive Description Study from Kenya, South Africa, and Canada

Outcomes and Multimorbidity among Children and Youth with Chronic Neurologic Disorders Hospitalized for COVID-19: A Canadian Immunization Monitoring Program, ACTive Study.

SARS-CoV-2 Coinfections and Severity in Hospitalized Children With Systematic Testing.

"I know how important it is": A qualitative analysis of participants' experiences in a vaccine safety study.

Immunogenicity and Safety of Live Attenuated Varicella Vaccine in Children and Youth With Solid Organ Transplants in Canada: A Canadian Immunization Research Network Study.

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Three Doses and Six Months Later: Real-World SARS-CoV-2 Specific Humoral and Cell-Mediated Immunity in Children With Inborn Errors of Immunity.

Frequent collaborators

Manish Sadarangani

Julie Bettinger

Scott Halperin

Shaun Morris

Jesse Papenburg

Gaston De Serres

Wendy Vaudry

Otto Vanderkooi

Jeffrey (Des) Pernica

James Kellner

Fatima Kakkar

Nora Macdonald

Olivier Drouin

Cora-Mihaela Constantinescu

Jeffrey Pernica

Charlotte Moore-Hepburn

Jennifer Isenor

Cheryl Foo

Jared Bullard

Juthaporn Cowan

Allison McGeer

Joanne Langley

Louis Valiquette

Alex Carignan

Krista Baerg

Joan Robinson

Tala El Tal

Bruce Smith

Julia Upton

Ari Bitnun

Hugo Chapdelaine

Lisa Knisley

Bruce Wright

Mike Benigeri

Sarah Tehseen

Kirk Leifso

Elaine Yong

Lucie Richard

Yaron Avitzur

Ronald Laxer