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Alex Carignan

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ProfessorDépartement de microbiologie et d'infectiologieUniversité de Sherbrooke

Alex Carignan

Professor

Département de microbiologie et d'infectiologie

Université de Sherbrooke

Sherbrooke, Quebec, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
32 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 3 research grants (2 FRQS, 1 CIHR), most recently in 2025.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

2,310

Citations

169

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their Université de Sherbrooke profile.

C. Difficile Clostridioides Difficile Infection Diarrhea Fidaxomicin Nosocomial Infection Placebo Controlled Platform Trial Randomized Controlled Trial

Latest papers

Procalcitonin to Guide 7 vs 14 Days of Antibiotics in Bloodstream Infections
JAMA Network Open · 2026
Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study
Human Vaccines & Immunotherapeutics · 2026
Secondary Prophylaxis of Recurrent Clostridioides difficile Infections During Systemic Antibiotics with Vancomycin (SPORES-V): study protocol for a randomized controlled trial
Trials · 2026

All 98 publications

Latest funding

Strategies for the Treatment and Prevention of Recurrent Clostridioides difficile infection: The SPORES Platform
CIHR · 2025 · Principal investigator
$2,015,775
Prevention of Infections in Cardiac Surgery (PICS): a cluster-randomized factorial cross-over trial
CIHR · 2024 · Co-investigator
$2,142,000
Prevention of Infections in Cardiac Surgery (PICS): a cluster-randomized factorial cross-over trial
CIHR · 2023 · Co-investigator
$100,000

All 15 grants and awards

98 publications.

Procalcitonin to Guide 7 vs 14 Days of Antibiotics in Bloodstream Infections

Ramendra R, Wright JK, Kain KC, Kim B, Mishra H, Zhong K, Aslanian P, Carignan A, Conly J, Detsky M

JAMA Network Open20262 citationsOpen Access

DOI: 10.1001/jamanetworkopen.2026.20973

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Smolinski M, Chew JL, Constantinescu C, Buchan CA, Burton C, Carignan A, Castellucci LA, Suresh S, McConnell A, Morris SK

Human Vaccines & Immunotherapeutics20262 citationsOpen Access

DOI: 10.1080/21645515.2026.2644030

Secondary Prophylaxis of Recurrent Clostridioides difficile Infections During Systemic Antibiotics with Vancomycin (SPORES-V): study protocol for a randomized controlled trial

Prosty C, Carignan A, Chan AK, Chen Y, Daley P, Daneman N, Kandel C, Longtin Y, Perez-Patrigeon S, Wuerz T

Trials20261 citationsOpen Access

DOI: 10.1186/s13063-026-09883-1

Duration of Therapy for Pseudomonas aeruginosa Bacteremia—A Post Hoc Subgroup Analysis From the BALANCE Randomized Controlled Trial

Yahav D, Pinto R, Cook D, Davis J, Duan E, Hoffman T, Lee TC, McDonald EG, Morpeth S, Muscedere J

Clinical Infectious Diseases20261 citations

DOI: 10.1093/cid/ciag144

Duration of antibiotic therapy for bacteremia in immune compromised hosts—a post hoc subgroup analysis of the BALANCE randomized clinical trial

Hamani M, Pinto R, Lee TC, MacFadden D, McDonald EG, Sligl W, Fowler RA, Daneman N, consortium TB, Daneman N

Clinical Microbiology and Infection (CMI)20261 citationsOpen Access

DOI: 10.1016/j.cmi.2026.06.003

P-559. Cohort of Individuals Bitten by a Tick and Prospective Evaluation of Post-Exposure Prophylaxis for Lyme Disease in Quebec (BQTick): a Pilot Study

Lorraine De Grâce, J Pelletier, Jeanne Tremblay, Véronique Noël, Alex Carignan

Open Forum Infectious Diseases2026Senior authorOpen Access

DOI: 10.1093/ofid/ofaf695.774

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Michael Smolinski, Jo Lin Chew, Cora Constantinescu, C. Arianne Buchan, Catherine Burton, Alex Carignan, Lana A. Castellucci, Sneha Suresh, Athena McConnell, Shaun K. Morris, Monika Naus, Jeffrey M. Pernica, Anne Pham-Huy, Pierre-Philippe Piché-Renaud, Manish Sadarangani, Karina A. Top, Juthaporn Cowan

Figshare2026Open Access

DOI: 10.6084/m9.figshare.31803759.v1

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Figshare2026Open Access

DOI: 10.6084/m9.figshare.31803759

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections

Daneman N, Rishu A, Pinto R, Rogers BA, Shehabi Y, Parke R, Cook D, Arabi Y, Muscedere J, Reynolds S

New England Journal of Medicine2025167 citations

DOI: 10.1056/nejmoa2404991

Neurological adverse events following COVID-19 vaccination among Canadians referred to the special immunization clinic network.

Fitzpatrick T, Yamoah P, Summerby-Murray D, Cowan J, Sadarangani M, Wright A, Belga S, Constantinescu C, Carignan A, McConnell A, Top KA, Canadian Immunization Research Network Investigators

Vaccine20253 citationsOpen Access

DOI: 10.1016/j.vaccine.2025.127254 PMID: 40398329

Strategies for the Treatment and Prevention of Recurrent Clostridioides difficile infection: The SPORES Platform

Principal investigatorCIHR2025Project Grant

Principal investigators: McDonald, Emily G; Carignan, Alex; Chan, Adrienne; Chen, Yan; Daley, Peter; Daneman, Nick; Kandel, Christopher; Lee, Todd C; Longtin, Yves; Perez Patrigeon, Santiago; Wuerz, Terence

Keywords: C. Difficile; Clostridioides Difficile Infection; Diarrhea; Fidaxomicin; Nosocomial Infection; Placebo Controlled; Platform Trial; Randomized Controlled Trial; Recurrence; Vancomycin

$2,015,775

Prevention of Infections in Cardiac Surgery (PICS): a cluster-randomized factorial cross-over trial

Co-investigatorCIHR2024Project Grant

Principal investigators: Mertz, Dominik

Keywords: Cardiac Surgery; Prophylactic Antibiotics

$2,142,000

Prevention of Infections in Cardiac Surgery (PICS): a cluster-randomized factorial cross-over trial

Co-investigatorCIHR2023Project Grant

Principal investigators: Mertz, Dominik

Keywords: Cardiac Surgery; Prophylactic Antibiotics

$100,000

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects

Principal investigators: Daneman, Nick; Murthy, Srinivas; Yamamura, Deborah L; Fowler, Robert A; Johnstone, Jennie; Lee, Todd C; MacFadden, Derek R; McDonald, Emily G; Paterson, David L; Rogers, Benjamin A; Yahav, Dafna

Keywords: Adaptive Platform Trial; Antibiotic De-Escalation; Antibiotic Step-Down; Antimicrobial Resistance; Bloodstream Infection; Central Venous Catheter Infection; Gram Negative Bacteremia; Randomized Controlled Trial

$2,919,785

Expanding the Staphylococcus Aureus Network Adaptive Platform (SNAP^2)

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects

Principal investigators: Lee, Todd C; Cheng, Matthew P; Daneman, Nick; Davis, Joshua; Goodman, Anna L; Johnstone, Jennie; Lawandi, Alexander; Lye, David C; McDonald, Emily G; Paul, Mical; Tong, Steven; Walls, Genevieve; Wuerz, Terence

Keywords: Combination Therapy; Endocarditis; Randomized Controlled Trial; Staphylococcus Aureus Bacteremia

$1,999,745

Expanding the Staphylococcus Aureus Network Adaptive Platform (SNAP^2)

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

Keywords: Combination Therapy; Endocarditis; Randomized Controlled Trial; Staphylococcus Aureus Bacteremia

$499,936

BALANCE+: A Platform Trial for Gram Negative Bloodstream Infections

Co-investigatorCIHR2022Operating Grant: Clinical Trials Projects - Indirect Costs

$729,947

PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)

Co-investigatorCIHR2021Project Grant

Principal investigators: Lee, Todd C; Cheng, Matthew P; McDonald, Emily G

Keywords: Antibiotic Resistance; Bacteremia; Bloodstream Infection; E. Coli; Esbl; K. Pneumoniae; Non-Inferiority; Pragmatic; Randomized Controlled Trial

$371,024

Canadian Immunization Research Network: COVID-19 Vaccine Readiness

Co-investigatorCIHR2020Canadian Immunization Research Network: COVID-19 Vaccine Readiness Funding Opp

Principal investigators: Halperin, Scott A; Andrew, Melissa K; Bettinger, Julie A; Bolotin, Shelly; Brisson, Marc; De Serres, Gaston; De Wals, Philippe; Deeks, Shelley L; Dubé, Eve; Hatchette, Todd F; Kellner, James D; Kwong, Jeffrey C; Langley, Joanne M; Loeb, Mark B; MacDonald, Shannon E; McNeil, Shelly A; Top, Karina A; Ward, Brian J

Keywords: Adverse Events Following Immunization; Clinical Trials Capacity And Readiness; Immunogenicity; Knowledge Translation; Population-Based Methodology; Rapid Response Research Capacity; Vaccine Coverage; Vaccine Hesitancy; Vaccine Modeling; Vaccine Safety And Effectiveness

The S. aureus Network Adaptive Platform Trial (SNAP) Canada: A Randomized Controlled Trial for Penicillin-susceptible, Methicillin-susceptible, and Methicillin-resistant Staphylococcus aureus Bloodstream Infections in Hospitalized Patients

Co-investigatorCIHR2020Project Grant

Principal investigators: Cheng, Matthew P; Daneman, Nick; Johnstone, Jennie; Lee, Todd C

Keywords: Bacteremia; Randomized Controlled Trial; Staphylococcus Aureus

$1,139,852

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Alex Carignan

Research

Latest papers

Latest funding

Procalcitonin to Guide 7 vs 14 Days of Antibiotics in Bloodstream Infections

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Secondary Prophylaxis of Recurrent Clostridioides difficile Infections During Systemic Antibiotics with Vancomycin (SPORES-V): study protocol for a randomized controlled trial

Duration of Therapy for Pseudomonas aeruginosa Bacteremia—A Post Hoc Subgroup Analysis From the BALANCE Randomized Controlled Trial

Duration of antibiotic therapy for bacteremia in immune compromised hosts—a post hoc subgroup analysis of the BALANCE randomized clinical trial

P-559. Cohort of Individuals Bitten by a Tick and Prospective Evaluation of Post-Exposure Prophylaxis for Lyme Disease in Quebec (BQTick): a Pilot Study

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Hematologic adverse events following COVID-19 vaccination and revaccination in persons aged 12 and above: A Canadian Immunization Research Network study

Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections

Neurological adverse events following COVID-19 vaccination among Canadians referred to the special immunization clinic network.

Frequent collaborators

Gaston De Serres

Louis Valiquette

Philippe Lagacé-Wiens

Johannes Delport

Robert Slinger

Marc Desjardins

Denis Talbot

Vivian Loo

Marc Brisson

Andrew Walkty

Susan Poutanen

Danuta Skowronski

James Karlowsky

Philippe Martin

Manish Sadarangani

Heather Adam

Karina Top

Nick Daneman

Caroline Quach

Simon Lévesque

John Muscedere

Ruxandra Pinto

Jeffrey Pernica

Lucie Richard

Pierre Aslanian

Catherine Bouchard

Maria Abou-Khalil

Nicholas Brousseau

Louiselle LeBlanc

Chantal Sauvageau

Vincent Masse

David Mathieu

Paul Bessette

Hugo Chapdelaine