Sujata Persad, University of Alberta

Research

Read how they describe their research on their University of Alberta profile.

Latest papers

Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage.
Cell death discovery · 2025
Molecular Mechanisms Regulating Epithelial Mesenchymal Transition (EMT) to Promote Cancer Progression.
International journal of molecular sciences · 2025 · senior author
Regulation of the Epithelial to Mesenchymal Transition in Osteosarcoma.
Biomolecules · 2023 · senior author

All 15 publications

Latest funding

Acquired abnormalities in the hemostatic system in obese children prone to Type 2 diabetes: Mechanisms and interventions for risk of cardiovascular disease.
CIHR · 2011 · Co-investigator
$275,472

All 1 grants and awards

15 publications.

01

Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage.

Abuetabh Y, Wu HH, Al Yousef H, Persad S, Schlosser MP, Eisenstat DD, Sergi CM, Leng R

Cell death discovery20253 citationsOpen Access

DOI: 10.1038/s41420-025-02441-9 PMID: 40175346

02

Molecular Mechanisms Regulating Epithelial Mesenchymal Transition (EMT) to Promote Cancer Progression.

Ghafoor S, Garcia E, Jay DJ, Persad S

International journal of molecular sciences2025Senior author

DOI: 10.3390/ijms26094364 PMID: 40362600

03

Regulation of the Epithelial to Mesenchymal Transition in Osteosarcoma.

Hinton K, Kirk A, Paul P, Persad S

Biomolecules2023Senior author

DOI: 10.3390/biom13020398 PMID: 36830767

04

DNA damage response revisited: the p53 family and its regulators provide endless cancer therapy opportunities.

Abuetabh Y, Wu HH, Chai C, Al Yousef H, Persad S, Sergi CM, Leng R

Experimental & molecular medicine2022276 citationsOpen Access

DOI: 10.1038/s12276-022-00863-4 PMID: 36207426

05

Epithelial-mesenchymal transition, regulated by β-catenin and Twist, leads to esophageal wall remodeling in pediatric eosinophilic esophagitis.

Garcia E, Ladak Z, Landry T, Wollin M, Persad ARL, Sergi CM, Huynh HQ, Persad R, Persad S

PloS one2022Senior author

DOI: 10.1371/journal.pone.0264622 PMID: 35239721

06

Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition

Elizabeth P. Garcia, I.F. de Luna, Kaya L. Persad, Kate C. Agopsowicz, David Jay, Frederick G. West, Mary Hitt, Sujata Persad

Scientific Reports202128 citationsSenior authorOpen Access

DOI: 10.1038/s41598-021-91344-7 PMID: 34083676

07

Sulforaphane (SFA) protects neuronal cells from oxygen & glucose deprivation (OGD)

Zeenat Ladak, Elizabeth Garcia, Jenny Yoon, Takaaki Landry, Edward A. Armstrong, Jerome Y. Yager, Sujata Persad

PLoS ONE202114 citationsSenior authorOpen Access

DOI: 10.1371/journal.pone.0248777 PMID: 33735260

08

Graphene Oxide Nanoparticles Induce Apoptosis in wild-type and CRISPR/Cas9-IGF/IGFBP3 knocked-out Osteosarcoma Cells.

Burnett M, Abuetabh Y, Wronski A, Shen F, Persad S, Leng R, Eisenstat D, Sergi C

Journal of Cancer202052 citationsOpen Access

DOI: 10.7150/jca.46464 PMID: 32742448

09

Osteosarcoma progression is associated with increased nuclear levels and transcriptional activity of activated β-Catenin.

Ali N, Venkateswaran G, Garcia E, Landry T, McColl H, Sergi C, Persad A, Abuetabh Y, Eisenstat DD, Persad S

Genes & cancer2019Senior author

DOI: 10.18632/genesandcancer.191 PMID: 31258833

10

Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A.

Persad A, Venkateswaran G, Hao L, Garcia ME, Yoon J, Sidhu J, Persad S

Genes & cancer2016Senior author

DOI: 10.18632/genesandcancer.128 PMID: 28191283

Acquired abnormalities in the hemostatic system in obese children prone to Type 2 diabetes: Mechanisms and interventions for risk of cardiovascular disease.

Co-investigatorCIHR2011Operating Grant

Principal investigators: Mitchell, Lesley G

Keywords: Animal Models; Blood Proteins; Cardiovascular Disease; Cell Signalling; Clinical Studies; Coagulation/Fibrinolytic Capacity; Gene Expression; Obesity; Pediatrics; Type 2 Diabetes

$275,472

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Frequent collaborators

Pediatrics Dept
Laboratory Medicine & Pathology Dept
Chemistry
Department of Pathology and Laboratory Medicine

Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Roger Leng

Laboratory Medicine & Pathology Dept

3 shared papers, latest 2025

Hao Li

Department of Pathology and Laboratory Medicine

1 shared papers, latest 2012

Jerome Yager

Pediatrics Dept

1 shared papers, latest 2021

Frederick West

Chemistry

1 shared papers, latest 2021

Rabin Persad

Pediatrics Dept

1 shared papers, latest 2015

Write to this professor

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Applying for

Paper to mention

Subject: Prospective PhD student Dear Professor Persad, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Sujata Persad

Research

Latest papers

Latest funding

Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage.

Molecular Mechanisms Regulating Epithelial Mesenchymal Transition (EMT) to Promote Cancer Progression.

Regulation of the Epithelial to Mesenchymal Transition in Osteosarcoma.

DNA damage response revisited: the p53 family and its regulators provide endless cancer therapy opportunities.

Epithelial-mesenchymal transition, regulated by &#x3b2;-catenin and Twist, leads to esophageal wall remodeling in pediatric eosinophilic esophagitis.

Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition

Sulforaphane (SFA) protects neuronal cells from oxygen & glucose deprivation (OGD)

Graphene Oxide Nanoparticles Induce Apoptosis in wild-type and CRISPR/Cas9-IGF/IGFBP3 knocked-out Osteosarcoma Cells.

Osteosarcoma progression is associated with increased nuclear levels and transcriptional activity of activated &#x3b2;-Catenin.

Active &#x3b2;-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A.

Acquired abnormalities in the hemostatic system in obese children prone to Type 2 diabetes: Mechanisms and interventions for risk of cardiovascular disease.

Frequent collaborators

Roger Leng

Hao Li

Jerome Yager

Frederick West

Rabin Persad

Epithelial-mesenchymal transition, regulated by β-catenin and Twist, leads to esophageal wall remodeling in pediatric eosinophilic esophagitis.

Osteosarcoma progression is associated with increased nuclear levels and transcriptional activity of activated β-Catenin.

Active β-catenin is regulated by the PTEN/PI3 kinase pathway: a role for protein phosphatase PP2A.