Bas Surewaard, University of Calgary

Research

Bacterial Pathogenesis Bloodstream Infections Infection Biology Innate Immunity Kupffer Cells Microbiology Salmonella Spp Crc

Latest papers

Vaccine-induced antibodies can limit Salmonella infection in the absence of complement or macrophages.
mBio · 2026
The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by dendritic cells.
Science immunology · 2024
Tacrolimus Impairs Kupffer Cell Capacity to Control Bacteremia: Why Transplant Recipients Are Susceptible to Infection.
Hepatology (Baltimore, Md.) · 2021

All 3 publications

Latest funding

Microscopy-Driven Insights into Salmonella O-Antigen's Role in Kupffer Cell Immune Evasion during Bloodstream Infections
CIHR · 2025 · Nominated PI
$963,900
Mechanisms of sex-biased illness severity in sepsis and implications for treatment
CIHR · 2024 · Co-investigator
$730,576
Canada Research Chairs - Tier 2
CIHR · 2022 · Nominated PI
$600,000

All 3 grants and awards

3 publications.

01

Vaccine-induced antibodies can limit Salmonella infection in the absence of complement or macrophages.

Perez-Toledo M, Aksu-Istil K, Marcial-Juarez E, Persaud RR, Alshayea A, Jossi SE, Carestia A, von Meijenfeld F, Botto M, James LC, Surewaard B, Afzal Z, Shields AM, Horsnell WG, Lopez-Macias C, Henderson IR, OptiVaNTS consortium, Jenne CN, Cunningham AF

mBio2026

DOI: 10.1128/mbio.02846-25 PMID: 41738756

02

The pore-forming apolipoprotein APOL7C drives phagosomal rupture and antigen cross-presentation by dendritic cells.

Gonzales GA, Huang S, Wilkinson L, Nguyen JA, Sikdar S, Piot C, Naumenko V, Rajwani J, Wood CM, Dinh I, Moore M, Cedeño E, McKenna N, Polyak MJ, Amidian S, Ebacher V, Rosin NL, Carneiro MB, Surewaard B, Peters NC, Mody CH, Biernaskie J, Yates RM, Mahoney DJ, Canton J

Science immunology2024

DOI: 10.1126/sciimmunol.adn2168 PMID: 39485861

03

Tacrolimus Impairs Kupffer Cell Capacity to Control Bacteremia: Why Transplant Recipients Are Susceptible to Infection.

Deppermann C, Peiseler M, Zindel J, Zbytnuik L, Lee WY, Pasini E, Baciu C, Matelski J, Lee Y, Kumar D, Humar A, Surewaard B, Kubes P, Bhat M

Hepatology (Baltimore, Md.)2021

DOI: 10.1002/hep.31499 PMID: 32761929

Microscopy-Driven Insights into Salmonella O-Antigen's Role in Kupffer Cell Immune Evasion during Bloodstream Infections

Nominated PICIHR2025Project Grant

Principal investigators: Surewaard, Bas G

Keywords: Bacterial Pathogenesis; Bloodstream Infections; Infection Biology; Innate Immunity; Kupffer Cells; Microbiology; Salmonella Spp

$963,900

Mechanisms of sex-biased illness severity in sepsis and implications for treatment

Co-investigatorCIHR2024Project Grant

Principal investigators: McDonald, Braedon A

Keywords: Biological Sex; Infection Resistance; Mouse Models; Sepsis

$730,576

Canada Research Chairs - Tier 2

Nominated PICIHR2022Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Surewaard, Bas G

Keywords: Crc

$600,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Infectious Diseases
Medical Microbiology and Infectious Diseases
Comparative Biology and Experimental Medicine
Transplant Program
Physiology and Pharmacology

Co-authors at University of Calgary, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Paul Kubes

Physiology and Pharmacology

1 shared papers, latest 2021

Mamatha Bhat

Transplant Program

1 shared papers, latest 2021

Atul Humar

Infectious Diseases

1 shared papers, latest 2021

Deepali Kumar

Infectious Diseases

1 shared papers, latest 2021

Johnathan Canton

Comparative Biology and Experimental Medicine

1 shared papers, latest 2024

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Bacterial Pathogenesis Dear Professor Surewaard, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Vaccine-induced antibodies can limit Salmonella infection in the absence of complement or macrophages." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Microscopy-Driven Insights into Salmonella O-Antigen's Role in Kupffer Cell Immune Evasion during Bloodstream Infections" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]