David Schriemer, University of Calgary

Research

Read how they describe their research on their University of Calgary profile.

Integrative structural biology Clinical proteomics

Latest papers

mosaicMPI: a framework for modular data integration across cohorts and -omics modalities.
Nucleic acids research · 2024
All-in-One Pseudo-MS3 Method for the Analysis of Gas-Phase Cleavable Protein Crosslinking Reactions.
Journal of the American Society for Mass Spectrometry · 2023 · senior author
Apparatus for Automated Continuous Hydrogen Deuterium Exchange Mass Spectrometry Measurements from Milliseconds to Hours.
Analytical chemistry · 2023

All 6 publications

Latest funding

Next-generation bioanalytical concepts and systems for structural proteomics
NSERC · 2023 · Principal investigator
$134,000
High-throughput Functional Dissection of PCNA Modifications that Promote Genome Stability in Human Cells
CIHR · 2023 · Principal investigator
$914,175
Oxygen-Regulated Tissue Culturing for Accurate In Virto Cell Analyses
NSERC · 2022 · Co-investigator
$150,000

All 17 grants and awards

6 publications.

01

mosaicMPI: a framework for modular data integration across cohorts and -omics modalities.

Verhey TB, Seo H, Gillmor A, Thoppey-Manoharan V, Schriemer D, Morrissy S

Nucleic acids research2024

DOI: 10.1093/nar/gkae442 PMID: 38813827

02

All-in-One Pseudo-MS3 Method for the Analysis of Gas-Phase Cleavable Protein Crosslinking Reactions.

Brodie NI, Sarpe V, Crowder DA, Schriemer D

Journal of the American Society for Mass Spectrometry2023Senior author

DOI: 10.1021/jasms.3c00134 PMID: 37590165

03

Apparatus for Automated Continuous Hydrogen Deuterium Exchange Mass Spectrometry Measurements from Milliseconds to Hours.

Anacleto J, Lento C, Sarpe V, Maqsood A, Mehrazma B, Schriemer D, Wilson DJ

Analytical chemistry2023

DOI: 10.1021/acs.analchem.2c05003 PMID: 36880265

04

Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry.

Leitner A, Bonvin AMJJ, Borchers CH, Chalkley RJ, Chamot-Rooke J, Combe CW, Cox J, Dong MQ, Fischer L, Götze M, Gozzo FC, Heck AJR, Hoopmann MR, Huang L, Ishihama Y, Jones AR, Kalisman N, Kohlbacher O, Mechtler K, Moritz RL, Netz E, Novak P, Petrotchenko E, Sali A, Scheltema RA, Schmidt C, Schriemer D, Sinz A, Sobott F, Stengel F, Thalassinos K, Urlaub H, Viner R, Vizcaíno JA, Wilkins MR, Rappsilber J

Structure (London, England : 1993)2020

DOI: 10.1016/j.str.2020.09.011 PMID: 33065067

05

Nonenzymatic biotinylation of histone H2A.

Healy S, Heightman TD, Hohmann L, Schriemer D, Gravel RA

Protein science : a publication of the Protein Society2009

DOI: 10.1002/pro.37 PMID: 19160459

06

ING1 protein targeting to the nucleus by karyopherins is necessary for activation of p21.

Russell MW, Soliman MA, Schriemer D, Riabowol K

Biochemical and biophysical research communications2008

DOI: 10.1016/j.bbrc.2008.07.076 PMID: 18655775

Next-generation bioanalytical concepts and systems for structural proteomics

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Schriemer, David

Keywords: mass spectrometry; bioanalytical chemistry; proteomics; integrative structural biology; protein chemistry; computational modeling; computer algorithms

$134,000

High-throughput Functional Dissection of PCNA Modifications that Promote Genome Stability in Human Cells

Principal investigatorCIHR2023Project Grant

Principal investigators: Billon, Pierre; Schriemer, David C

Keywords: Crispr-Cas9; Dna Repair; Functional Genomics; Genome Editing; Genomic Stability; Mass Spectrometry; Pcna; Post-Translational Modifications; Prime Editing

$914,175

Oxygen-Regulated Tissue Culturing for Accurate In Virto Cell Analyses

Co-investigatorNSERC2022Research Tools and Instruments

Principal investigators: Riabowol, Karl

$150,000

NanoLC System for Ultrasensitive Hydrogen/Deuterium Exchange Mass Spectrometry

Principal investigatorNSERC2021Research Tools and Instruments

Principal investigators: Schriemer, David

$145,040

Integrative Structural Modeling of a Master End-Sensing Synapse in DNA Double Strand Break Repair

Nominated PICIHR2020Project Grant

Principal investigators: Schriemer, David C

Keywords: Crosslinking Mass Spectrometry; Dna Damage Signalling; Dna Repair; Electron Microscopy; Homologous Repair Recombination; Hydrogen Deuterium Exchange Mass Spectrometry; Non-Homologous End Joining; Protein Complexes; Protein-Dna Interactions

$849,150

Mass spec studio: business intelligence software for the international laboratory industry (a Phase IIb project)

Principal investigatorNSERC2020Idea to Innovation

Principal investigators: Schriemer, David

$251,544

Proteomics systems for integrative structural biology

Principal investigatorNSERC2017Discovery Grants Program - Accelerator Supplements

Principal investigators: Schriemer, David

$120,000

Mass spec studio software for the pharmaceutical market - a phase one project

Principal investigatorNSERC2017Idea to Innovation

Principal investigators: Schriemer, David

$125,000

Proteomics systems for integrative structural biology

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Schriemer, David

$744,000

Characterizing complex protein states with next generation HX-MS concepts

Principal investigatorNSERC2015Collaborative Research and Development Grants

Principal investigators: Schriemer, David

$366,800

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Department of Biochemistry and Molecular Biology

Co-authors at University of Calgary, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Karl Riabowol

Department of Biochemistry and Molecular Biology

1 shared papers, latest 2008

Sorana Morrissy

Department of Biochemistry and Molecular Biology

1 shared papers, latest 2024

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2023

Subject: Prospective PhD student: Integrative structural biology Dear Professor Schriemer, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "mosaicMPI: a framework for modular data integration across cohorts and -omics modalities." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Next-generation bioanalytical concepts and systems for structural proteomics" (2023), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]