Keith Sharkey

The Gut Microbiota as a Contributor to Sexual Dimorphism in Amyotrophic Lateral Sclerosis

Principal investigators: Nguyen, Minh Dang; Pfeffer, Gerald; Sharkey, Keith

Keywords: Amyotrophic Lateral Sclerosis; Bacteria And Their Metabolites; Energy Metabolism; Fecal Material Transplant; Gut Microbiome; Mitochondria; Neurodegeneration; Omics - Transcriptomics, Metagenomics, Metabolomics; Sexual Dimorphism; Transgenic & Germ-Free Mice

Neuroimmunophysiology of the Gastrointestinal Tract 2023

Principal investigators: Sharkey, Keith

Keywords: Enteric Nervous System; Gastrointestinal Tract; Gut Microbiota; Gut-Brain Axis; Inflammatory Bowel Disease; Irritable Bowel Syndrome

Peripheral Inflammation and Anxiety: Role of Endocannabinoid Signaling in the Amygdala

Principal investigators: Pittman, Quentin J

Keywords: Amygdala; Anxiety; Colitis; Crh; Cytokine; Endocannabinoid; Hpa Axis; Neuroinflammation

Enteric glia in the control of intestinal barrier function.

Principal investigators: Sharkey, Keith

Keywords: Enteric Glia; Enteric Microbiota; Enteric Nervous System; Enteroendocrine Cells; Epithelial Permeability; Intestinal Barrier Function; Serotonin; Ussing Chambers

Nutrient regulation of intestinal barrier function in health and inflammatory bowel disease.

Principal investigators: Cavin, Jean-Baptiste

Keywords: Enteric Glia; Enteric Nervous System; Gut Barrier Function; Inflammatory Bowel Diseases; Intestinal Inflammation; Nutrition

Enteric neural and glial control of gastrointestinal function in health and inflammatory disease.

Principal investigators: Sharkey, Keith

Keywords: Autonomic Nervous System; Brain-Gut Interactions; Colitis; Endocannabinoids; Enteric Glia; Enteric Nervous System; Intestinal Inflammation; Myenteric Plexus

Role of gustatory insular cortex endocannabinoid system function in the stress-relieving effects of comfort feeding

Principal investigators: Sticht, Martin A

Keywords: Addiction; Brain; Comfort Feeding; Endocannabinoids; Insular Cortex; Intracranial Administration; Neuroscience; Pharmacology; Physiology; Stress

Enteric neural regulation of barrier function in the intestine

Principal investigators: MacNaughton, Wallace

Brain Dysfunction in Chronic Inflammatory Disease: Reciprocal Effects of CNS and Periphery Crosstalk

Principal investigators: Swain, Mark G

Keywords: Chronic Inflammation; Illness Behavior; Immune-Mediated Diseases; Inflammation; Inflammatory Bowel Disease; Liver Disease; Neurocognition; Neuroimaging; Quality Of Life; Rheumatoid Arthritis

Brain Dysfunction in Chronic Inflammatory Disease: Reciprocal Effects of CNS and Periphery Crosstalk

Principal investigators: Swain, Mark G

Keywords: Brain Dysfunction; Brain-Body Interface; Chronic Inflammation; Cognition And Affect; Functional Mri; Health Outcomes And Economics; Inflammatory Bowel Disease; Liver Disease; Patients Cohort; Sickness Behaviors