Faculty profile

Mark Swain

ResearcherMedicineUniversity of Calgary

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Calgary directory, so their courses and email address may be missing. Find their university profile.

Mark Swain

Researcher

Medicine

Health Sciences

University of Calgary

Calgary, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
19 publications in the last five years, latest in 2026.
Principal investigator on 4 research grants (4 CIHR), most recently in 2022.
Supervisor on 2 trainee awards (2 CIHR), most recently in 2009.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Chronic Inflammation Inflammatory Bowel Disease Liver Disease Clinical Care Pathway Clinical Decision Support Tool Primary Care Illness Behavior Immune-Mediated Diseases

Latest papers

Symptom burden is associated with health-related quality of life in symptomatic adults with primary sclerosing cholangitis.
Hepatology communications · 2026
Time-Varying Impact of Steatosis and Alcohol on Mortality: A Marginal Structural Model of the Canadian Longitudinal Study on Aging.
Liver international : official journal of the International Association for the Study of the Liver · 2026
Machine Learning Predicts Treatment Response and Prognostic Pathways From Whole-Blood Transcriptome in Primary Biliary Cholangitis.
Liver international : official journal of the International Association for the Study of the Liver · 2026

All 30 publications

Latest funding

Mechanistic Dissection of Gut Microbiota-Immune Interactions Driving MASLD Progression
CIHR · 2025 · Co-investigator
$994,500
Evaluate, validate and refine the first clinical care pathway to risk-stratify patients with alcohol-related liver disease
CIHR · 2022 · Principal investigator
$455,176
Understanding and Responding to the COVID-19 Pandemic Effect on the Magnitude of Alcohol-Related Liver Disease in Alberta.
CIHR · 2021 · Co-investigator
$422,863

All 11 grants and awards

30 publications.

Symptom burden is associated with health-related quality of life in symptomatic adults with primary sclerosing cholangitis.

Evon DM, Merkler K, Anderson C, Deutsch-Link S, Gomel R, Hatchett J, Safer R, Rossi SJ, Bowlus CL, Swain M, Reeve BB

Hepatology communications2026

DOI: 10.1097/hc9.0000000000001009 PMID: 42623524

Time-Varying Impact of Steatosis and Alcohol on Mortality: A Marginal Structural Model of the Canadian Longitudinal Study on Aging.

Rapino C, Sebastiani G, Burnside J, Wen C, Ramji A, Swain M, Patel K, Saeed S

Liver international : official journal of the International Association for the Study of the Liver2026

DOI: 10.1111/liv.70833 PMID: 42557925

Machine Learning Predicts Treatment Response and Prognostic Pathways From Whole-Blood Transcriptome in Primary Biliary Cholangitis.

Syed H, Sun N, Waly D, Verma V, Smith M, Shapiro D, Erickson M, Siminovitch K, Swain M, Osman MS, Mason AL

Liver international : official journal of the International Association for the Study of the Liver2026

DOI: 10.1111/liv.70764 PMID: 42449558

Reduced wait times for hepatology referrals in a prospective quality improvement initiative.

Joe-Uzuegbu O, Sachar Y, Shaheen AA, Congly S, Burak KW, Heather G, Ormond C, Sadler MD, Borman MA, Dong V, Nguyen HH, Aspinall AI, Wang P, Frolkis A, Coffin CS, Stinton LM, Swain M, Brahmania M

Hepatology communications2026

DOI: 10.1097/hc9.0000000000000952 PMID: 42172507

Wastewater-based surveillance of hepatitis A virus across municipalities and neighbourhoods in Alberta, Canada.

Weyant RB, Ueno A, Waddell B, Lee J, Bhardwaj T, Acosta N, Xiang K, Sarabi S, Bertazzon S, Bender A, Visser G, McCalder J, Papparis C, Bautista Chavarriaga M, Clark RG, Fonseca K, Borlang J, Lee E, Swain M, Coffin CS, Lee B, Pang X, Cabaj J, O'Grady C, Conly JM, Hubert CRJ, Parkins MD

The Science of the total environment2026

DOI: 10.1016/j.scitotenv.2026.181421 PMID: 41671811

Part 1: CAR Metabolic Dysfunction-Associated Steatotic Liver Disease Working Group Guidance Statements for Detecting and Grading Hepatic Steatosis Using Ultrasound, CT, or MRI.

Wilson MP, Tang A, Low G, Zhang LX, Costa AF, Pang E, Chang S, Medellin A, Shaheen AA, Dana J, Millo N, Kielar A, Swain M, Leung V, Fung D, Hurrell C, Fung C

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes2026

DOI: 10.1177/08465371251357444 PMID: 40765159

Part 3: CAR Metabolic Dysfunction-Associated Steatotic Liver Disease Working Group Recommendations for Ultrasound Shear Wave Elastography and MR Elastography Program Implementation, Funding, and Quality Assurance.

Wilson MP, Low G, Medellin A, Chang SD, Pang E, Whitaker T, Costa AF, Tang A, Dana J, Millo N, Kielar A, Zhang LX, Shaheen AA, Swain M, Leung V, Fung D, Hurrell C, Fung C

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes2026

DOI: 10.1177/08465371251357446 PMID: 40765155

Part 2: CAR Metabolic Dysfunction-Associated Steatotic Liver Disease Working Group Recommendations for Risk Stratifying Patients With MASLD.

Wilson MP, Low G, Shaheen AA, Costa AF, Tang A, Pang E, Chang S, Medellin A, Dana J, Millo N, Kielar A, Zhang LX, Whitaker T, Swain M, Leung V, Fung D, Hurrell C, Fung C

Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes2026

DOI: 10.1177/08465371251357447 PMID: 40765154

Sex differences in the prevalence and cardiometabolic risk profiles of steatotic liver disease: A Canadian Longitudinal Study on Aging analysis.

Burnside J, Cinque F, Sebastiani G, Ramji A, Patel K, Swain M, Saeed S

Canadian journal of public health = Revue canadienne de sante publique2026

DOI: 10.17269/s41997-025-01025-5 PMID: 40323353

Call to action: integrating steatotic liver disease into public health strategies in Canada.

Saeed S, Burnside J, Wen C, Rapino C, Patel K, Ramji A, Swain M, Sebastiani G

Lancet regional health. Americas2025

DOI: 10.1016/j.lana.2025.101278 PMID: 41209818

Mechanistic Dissection of Gut Microbiota-Immune Interactions Driving MASLD Progression

Co-investigatorCIHR2025Project Grant

Principal investigators: Nguyen, Henry H

Keywords: Adaptive Immunity ( T-Cells); Gnotobiotic Mice; Gut Microbiome; Gut-Liver Axis; Liver Fibrosis; Metabolic Dysfunction Associated Steatotic Liver Disease; Microbial Pathobionts; Patient Liver Biopsies; Precision Medicine; Transcriptomics

$994,500

Evaluate, validate and refine the first clinical care pathway to risk-stratify patients with alcohol-related liver disease

Principal investigatorCIHR2022Project Grant

Principal investigators: Shaheen, Abdel-Aziz M; Heitman, Steven J; McCaughey, Deirdre; Swain, Mark G

Keywords: Clinical Care Pathway; Clinical Decision Support Tool; Primary Care

$455,176

Understanding and Responding to the COVID-19 Pandemic Effect on the Magnitude of Alcohol-Related Liver Disease in Alberta.

Co-investigatorCIHR2021O. Gr.: Addr. the Health Impacts of COVID-19 - Imp. of def/disp care on health

Principal investigators: Shaheen, Abdel-Aziz M

Keywords: Develop Clinical Care Pathway; Evaluate Disease Burden; Primary Care Setting

$422,863

Developing and validating NAFLD advanced fibrosis diagnostic prediction model in primary care

Co-investigatorCIHR2019Project Grant

Principal investigators: Shaheen, Abdel-Aziz M; Kaplan, Gilaad G; Quan, Hude

Keywords: Clinical Decision Support Tool; Prediction Model; Primary Care Setting

$272,387

Brain Dysfunction in Chronic Inflammatory Disease: Reciprocal Effects of CNS and Periphery Crosstalk

Nominated PICIHR2013Team Grant: Health Challenges in Chronic Inflammation Initiative - (Full Appl)

Principal investigators: Swain, Mark G

Keywords: Chronic Inflammation; Illness Behavior; Immune-Mediated Diseases; Inflammation; Inflammatory Bowel Disease; Liver Disease; Neurocognition; Neuroimaging; Quality Of Life; Rheumatoid Arthritis

$2,292,479

A Multidisciplinary Approach To Target Chronic Inflammation Of The Gut, Liver And Joint.

Co-investigatorCIHR2013Team Grant: Health Challenges in Chronic Inflammation Initiative - (Full Appl)

Principal investigators: Eksteen, Johannes A

Keywords: Genetics; Gut Permeability; Inflammatory Bowel Disease; Innate Immunity; Personalized Medicine; Primary Sclerosing Cholangitis; Rheumatoid Arthritis

$2,443,500

Brain Dysfunction in Chronic Inflammatory Disease: Reciprocal Effects of CNS and Periphery Crosstalk

Nominated PICIHR2012Team Grant: Health Challenges in Chronic Inflammation Initiative (LOI)

Principal investigators: Swain, Mark G

Keywords: Brain Dysfunction; Brain-Body Interface; Chronic Inflammation; Cognition And Affect; Functional Mri; Health Outcomes And Economics; Inflammatory Bowel Disease; Liver Disease; Patients Cohort; Sickness Behaviors

A multidisciplinary approach to target chronic inflammation of the gut, liver and joint

Co-investigatorCIHR2012Team Grant: Health Challenges in Chronic Inflammation Initiative (LOI)

Principal investigators: Eksteen, Johannes A

Keywords: Autoimmune Hepatitis; Chemokines; Chrominc Inflammation; Gut Permeability; Ibd; Primary Sclerosing Cholangitis; Seronegative Arthritis

$13,000

Regulatory role of NK cells in the hepatic innate immune response

Nominated PICIHR2011Operating Grant

Principal investigators: Swain, Mark G

Keywords: Adoptive Transfer; Chemokine Receptors; Chemokines; Cytokines; Flow Cytometry; Hepatitis; Innate Immunity; Intravital Microscopy; Nk Cells; Nkt Cells

$617,840

Indoleamine 2,3-dioxygenase (IDO) Induction Within the Brain and the Generation of Sickness Behaviours in Mice with Inflammatory Liver Injury

SupervisorCIHR2009Master's Award: Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Nguyen, Kimchi

Keywords: 3-Dioxygenase; Bile Duct Resection; Cholestasis; Cns-Periphery Communication; Indoleamine 2; Neurotransmission; Sickness Behaviour; Tryptophan-Catabolism

$17,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Mark Swain

Research

Latest papers

Latest funding

Symptom burden is associated with health-related quality of life in symptomatic adults with primary sclerosing cholangitis.

Time-Varying Impact of Steatosis and Alcohol on Mortality: A Marginal Structural Model of the Canadian Longitudinal Study on Aging.

Machine Learning Predicts Treatment Response and Prognostic Pathways From Whole-Blood Transcriptome in Primary Biliary Cholangitis.

Reduced wait times for hepatology referrals in a prospective quality improvement initiative.

Wastewater-based surveillance of hepatitis A virus across municipalities and neighbourhoods in Alberta, Canada.

Part 1: CAR Metabolic Dysfunction-Associated Steatotic Liver Disease Working Group Guidance Statements for Detecting and Grading Hepatic Steatosis Using Ultrasound, CT, or MRI.

Part 3: CAR Metabolic Dysfunction-Associated Steatotic Liver Disease Working Group Recommendations for Ultrasound Shear Wave Elastography and MR Elastography Program Implementation, Funding, and Quality Assurance.

Part 2: CAR Metabolic Dysfunction-Associated Steatotic Liver Disease Working Group Recommendations for Risk Stratifying Patients With MASLD.

Sex differences in the prevalence and cardiometabolic risk profiles of steatotic liver disease: A Canadian Longitudinal Study on Aging analysis.

Call to action: integrating steatotic liver disease into public health strategies in Canada.

Frequent collaborators

Giada Sebastiani

Sahar Saeed

Abdel-Aziz Shaheen

Emily Pang

Gideon Hirschfield

Remo Panaccione

Nazia Selzner

Lusine Abrahamyan

Pere Santamaria

An Tang

Xiaoli Pang

Nauzer Forbes

Jason Cabaj

Christopher Ma

Amanda Ricciuto

Cathy Lu

Gilaad Kaplan

Kaberi Dasgupta

Gilaad Kaplan

Stefania Bertazzon

Sonya MacParland

Fiona Clement

Keith Sharkey