Faculty profile

Richard Frayne

ResearcherRadiologyUniversity of Calgary

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Calgary directory, so their courses may be missing. Find their university profile.

Richard Frayne

Researcher

Radiology

University of Calgary

Calgary, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
31 publications in the last five years, latest in 2026.
Senior (last) author on 5 recent papers, a sign of leading a research group.
Principal investigator on 9 research grants (5 NSERC, 4 CIHR), most recently in 2021.
Supervisor on 1 trainee award (1 CIHR), most recently in 2022.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

137

Publications

331

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Deep Learning Image Acqusition Image Reconstruction Image Science Magnetic Resonance (MR) Imaging Medical Physics Tomography Aging

Latest papers

Progressive and Short-Interval Changes Observed in the Corticospinal Tract and Corpus Callosum of Patients with Amyotrophic Lateral Sclerosis: A Texture Analysis Study.
AJNR. American journal of neuroradiology · 2026
MedShapeNet - a large-scale dataset of 3D medical shapes for computer vision.
Biomedizinische Technik. Biomedical engineering · 2025
Signature White Matter Hyperintensity Locations Associated With Vascular Risk Factors Derived From 15 653 Individuals.
Stroke · 2025

All 137 publications

Latest funding

Early-assymptomatic-dementia prediction based on a white-matter biomarker using Artificial Intelligence algorithms
CIHR · 2022 · Supervisor
Health Research Training to Address Vascular Contributions to Cognitive Decline: the Vascular Training (VAST) Platform
CIHR · 2021 · Co-investigator
$2,380,292
Advanced Deep Learning Approaches to Enhance Magnetic Resonance Tomography
NSERC · 2021 · Principal investigator
$200,000

All 25 grants and awards

137 publications.

Progressive and Short-Interval Changes Observed in the Corticospinal Tract and Corpus Callosum of Patients with Amyotrophic Lateral Sclerosis: A Texture Analysis Study.

Parnianpour P, Harrison M, Benatar M, Briemberg H, Dionne A, Dupré N, Frayne R, Genge A, Graham SJ, Korngut L, Seres P, Wilman A, Zinman L, Kalra S, Canadian ALS Neuroimaging Consortium (CALSNIC)

AJNR. American journal of neuroradiology2026

DOI: 10.3174/ajnr.a9013 PMID: 40968018

MedShapeNet - a large-scale dataset of 3D medical shapes for computer vision.

Li J, Zhou Z, Yang J, Pepe A, Gsaxner C, Luijten G, Qu C, Zhang T, Chen X, Li W, Wodzinski M, Friedrich P, Xie K, Jin Y, Ambigapathy N, Nasca E, Solak N, Melito GM, Vu VD, Memon AR, Schlachta C, De Ribaupierre S, Patel R, Eagleson R, Chen X, Mächler H, Kirschke JS, de la Rosa E, Christ PF, Li HB, Ellis DG, Aizenberg MR, Gatidis S, Küstner T, Shusharina N, Heller N, Andrearczyk V, Depeursinge A, Hatt M, Sekuboyina A, Löffler MT, Liebl H, Dorent R, Vercauteren T, Shapey J, Kujawa A, Cornelissen S, Langenhuizen P, Ben-Hamadou A, Rekik A, Pujades S, Boyer E, Bolelli F, Grana C, Lumetti L, Salehi H, Ma J, Zhang Y, Gharleghi R, Beier S, Sowmya A, Garza-Villarreal EA, Balducci T, Angeles-Valdez D, Souza R, Rittner L, Frayne R, Ji Y, Ferrari V, Chatterjee S, Dubost F, Schreiber S, Mattern H, Speck O, Haehn D, John C, Nürnberger A, Pedrosa J, Ferreira C, Aresta G, Cunha A, Campilho A, Suter Y, Garcia J, Lalande A, Vandenbossche V, Van Oevelen A, Duquesne K, Mekhzoum H, Vandemeulebroucke J, Audenaert E, Krebs C, van Leeuwen T, Vereecke E, Heidemeyer H, Röhrig R, Hölzle F, Badeli V, Krieger K, Gunzer M, Chen J, van Meegdenburg T, Dada A, Balzer M, Fragemann J, Jonske F, Rempe M, Malorodov S, Bahnsen FH, Seibold C, Jaus A, Marinov Z, Jaeger PF, Stiefelhagen R, Santos AS, Lindo M, Ferreira A, Alves V, Kamp M, Abourayya A, Nensa F, Hörst F, Brehmer A, Heine L, Hanusrichter Y, Weßling M, Dudda M, Podleska LE, Fink MA, Keyl J, Tserpes K, Kim MS, Elhabian S, Lamecker H, Zukić D, Paniagua B, Wachinger C, Urschler M, Duong L, Wasserthal J, Hoyer PF, Basu O, Maal T, Witjes MJH, Schiele G, Chang TC, Ahmadi SA, Luo P, Menze B, Reyes M, Deserno TM, Davatzikos C, Puladi B, Fua P, Yuille AL, Kleesiek J, Egger J

Biomedizinische Technik. Biomedical engineering2025

DOI: 10.1515/bmt-2024-0396 PMID: 39733351

Signature White Matter Hyperintensity Locations Associated With Vascular Risk Factors Derived From 15 653 Individuals.

Biesbroek JM, de Kort FAS, Anblagan D, Bastin ME, Beiser A, Brodaty H, Chaturvedi N, Chen CPLH, Cheng B, Cheng CY, Cox SR, DeCarli C, Enzinger C, Fletcher E, Frayne R, de Groot M, Hilal S, Huang F, Ikram MA, Jiang J, Lam BYK, Maillard P, Mayer C, McCreary CR, Mok V, Muñoz Maniega S, Petersen M, Roshchupkin G, Sachdev PS, Schmidt R, Seiler S, Seshadri S, Sudre CH, Thomalla G, Valdés Hernández M, Venketasubramanian N, Vernooij MW, Vinke EJ, Wardlaw JM, Wen W, Kuijf HJ, Biessels GJ

Stroke2025

DOI: 10.1161/strokeaha.125.051159 PMID: 40832713

Quantitative Susceptibility Mapping in Adults with Persistent Postconcussion Symptoms after Mild Traumatic Brain Injury: An Exploratory Study.

Bell TK, Ansari M, Joyce JM, Mercier LJ, Gobbi DG, Frayne R, Debert C, Harris AD

AJNR. American journal of neuroradiology2025

DOI: 10.3174/ajnr.a8454 PMID: 39151958

Cerebral white matter hyperintensity volumes: Normative age- and sex-specific values from 15 population-based cohorts comprising 14,876 individuals.

de Kort FAS, Vinke EJ, van der Lelij EJ, Anblagan D, Bastin ME, Beiser A, Brodaty H, Chaturvedi N, Cheng B, Cox SR, DeCarli C, Enzinger C, Fletcher E, Frayne R, de Groot M, Huang F, Ikram MA, Jiang J, Lam BYK, Maillard P, Mayer C, McCreary CR, Mok V, Maniega SM, Petersen M, Roshchupkin G, Sachdev PS, Schmidt R, Seiler S, Seshadri S, Sudre CH, Thomalla G, Twerenbold R, Valdés Hernández M, Vernooij MW, Wardlaw JM, Wen W, Kuijf HJ, Biessels GJ, Biesbroek JM

Neurobiology of aging2025

DOI: 10.1016/j.neurobiolaging.2024.11.006 PMID: 39602940

Age- and Sex-Specific Patterns in Adult Brain Network Segregation.

Sidhu AS, Duarte KTN, Shahid TH, Sharkey RJ, Lauzon ML, Salluzzi M, McCreary CR, Protzner AB, Goodyear BG, Frayne R

Human brain mapping2025Senior author

DOI: 10.1002/hbm.70169 PMID: 40084534

Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology

Xhima K, Ottoy J, Gibson E, Zukotynski K, Scott C, Feliciano GJ, Adamo S, Kuo PH, Borrie MJ, Chertkow H

Alzheimer's and Dementia20246 citationsOpen Access

DOI: 10.1002/alz.13791 PMID: W4393925641

Longitudinal analysis of glymphatic function in amyotrophic lateral sclerosis and primary lateral sclerosis.

Sharkey RJ, Cortese F, Goodyear BG, Korngut LW, Jacob SM, Sharkey KA, Kalra S, Nguyen MD, Frayne R, Pfeffer G

Brain : a journal of neurology2024

DOI: 10.1093/brain/awae288 PMID: 39241118

Multi-stage semi-supervised learning enhances white matter hyperintensity segmentation.

Duarte KTN, Sidhu AS, Barros MC, Gobbi DG, McCreary CR, Saad F, Camicioli R, Smith EE, Bento MP, Frayne R

Frontiers in computational neuroscience2024Senior author

DOI: 10.3389/fncom.2024.1487877 PMID: 39502452

Effect of MR head coil geometry on deep-learning-based MR image reconstruction.

Dubljevic N, Moore S, Lauzon ML, Souza R, Frayne R

Magnetic resonance in medicine2024Senior author

DOI: 10.1002/mrm.30130 PMID: 38647191

Early-assymptomatic-dementia prediction based on a white-matter biomarker using Artificial Intelligence algorithms

SupervisorCIHR2022Summer Program in Aging

Principal investigators: Duarte, Kaue T

Keywords: Artificial Intelligence; Brain Imaging; Disease; Heatlhcare Services; Machine Learning; Mental Health; Normal Aging

Health Research Training to Address Vascular Contributions to Cognitive Decline: the Vascular Training (VAST) Platform

Co-investigatorCIHR2021Tr. Grant: Health Research Training Platform - Vascular Cognitive Impairment

Principal investigators: Smith, Eric E; Badhwar, Amanpreet; Mazerolle, Erin L; Stefanovic, Bojana

Keywords: Vascular Cognitive Impairment

$2,380,292

Advanced Deep Learning Approaches to Enhance Magnetic Resonance Tomography

Principal investigatorNSERC2021Discovery Grants Program - Individual

Principal investigators: Frayne, Richard

Keywords: image science; medical physics; image reconstruction; image acqusition; magnetic resonance (mr) imaging; deep learning; tomography

$200,000

Prediction of multiple sclerosis disability worsening scores using multi-stream deep learning

Co-investigatorCIHR2020Project Grant

Principal investigators: Zhang, Yunyan

Keywords: Brain Pathology; Clinical Outcomes; Deep Machine Learning; Disease Worsening Score; Image Texture Analysis; Magnetic Resonance Imaging; Personalized Treatment; Relapsing Remitting Multiple Sclerosis; Secondary Progressive Multiple Sclerosis; Sustained Disability Worsening

$711,450

Prediction of multiple sclerosis disability worsening scores using multi-stream deep learning

Co-investigatorCIHR2019Project Grant - PA: Neurosciences, Mental Health and Addiction

Principal investigators: Zhang, Yunyan

Keywords: Brain Pathology; Clinical Variables; Deep Machine Learning; Disability Worsening Score; Magnetic Resonance Imaging; Multiple Sclerosis; Personalized Treatment; Relapsing Remitting Multiple Sclerosis; Secondary Progressive Multiple Sclerosis; Texture Analysis

$100,000

Magnetic Resonance Imaging Evaluation of NA1 Neuroprotection on Infarct Growth Following Endovascular Treatment for Acute Ischemic Stroke.

Co-investigatorCIHR2017Project Grant

Principal investigators: Barber, Philip A

Keywords: Acute Stroke; Endovascular Treatment; Infarct Growth; Magnetic Resonance Imaging; Neuroprotection

$466,650

HARmoNising Brain Imaging MEthodS for VaScular Contributions to Neurodegeneration (HARNESS)

Co-investigatorCIHR2016Working Groups in Brain Imaging Methods for Neurodegeneration

Principal investigators: Smith, Eric E; Wardlaw, Joanna

Keywords: Magnetic Resonance Imaging; Positron Emission Tomography; Vascular Cognitive

$73,000

Imaging Tools for Quick and Appropriate Triage of Stroke Patients

Co-investigatorCIHR2016Project Grant

Principal investigators: Menon, Bijoy K

Keywords: Acute Stroke Imaging Tool; Community Hospitals; Decision Making; Triage

$573,375

Understanding Neurodegeneration, Venules, Amyloid Imaging and Leukoaraiosis (UNVAIL)

Principal investigatorCIHR2016Project Grant

Principal investigators: Black, Sandra E; Bocti, Christian; Borrie, Michael J; Chertkow, Howard M; Darvesh, Sultan; Dowlatshahi, Dariush; Frayne, Richard; Hsiung, Ging-Yuek R; Laforce, Robert J; Mandzia, Jennifer L; Masellis, Mario; Prato, Frank S; Sahlas, Demetrios; Smith, Eric E; Soucy, Jean-Paul; Strother, Stephen; Swartz, Richard

Keywords: Amyloid And Tau Pet Imaging; Amyloid Angiopathy; Brain Volumetrics And Microstructural Integrity; Executive Dysfunction And Memory Loss; Executive Function Processing; Metabolic Imaging And Functional Networks; Small Vessel Disease; Stroke And Transient Ischemic Attack; Subcortical Ischemic Brain Small Blood Vessel Disasculopathy; Venous Collagenosis

$100,000

Promoting Brain Health to Prevent Dementia: Roles of Covert Vascular Brain Injury and Cognitive Reserve in Age-Related Cognitive Decline

Co-investigatorCIHR2016Foundation Grant

Principal investigators: Smith, Eric E

Keywords: Aging; Cognition; Dementia; Magnetic Resonance Imaging; Stroke

$2,856,357

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Richard Frayne

Research

Latest papers

Latest funding

Progressive and Short-Interval Changes Observed in the Corticospinal Tract and Corpus Callosum of Patients with Amyotrophic Lateral Sclerosis: A Texture Analysis Study.

MedShapeNet&#xa0;- a large-scale dataset of 3D medical shapes for computer vision.

Signature White Matter Hyperintensity Locations Associated With Vascular Risk Factors Derived From 15&#x2009;653 Individuals.

Quantitative Susceptibility Mapping in Adults with Persistent Postconcussion Symptoms after Mild Traumatic Brain Injury: An Exploratory Study.

Cerebral white matter hyperintensity volumes: Normative age- and sex-specific values from 15 population-based cohorts comprising 14,876 individuals.

Age- and Sex-Specific Patterns in Adult Brain Network Segregation.

Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology

Longitudinal analysis of glymphatic function in amyotrophic lateral sclerosis and primary lateral sclerosis.

Multi-stage semi-supervised learning enhances white matter hyperintensity segmentation.

Effect of MR head coil geometry on deep-learning-based MR image reconstruction.

Advanced Deep Learning Approaches to Enhance Magnetic Resonance Tomography

Frequent collaborators

Sanjay Kalra

Lawrence Korngut

Angela Genge

Christian Beaulieu

Roberto Souza

Demetrios Sahlas

Zahinoor Ismail

Maged Goubran

Jean-Paul Soucy

Paolo Federico

Michael Borrie

Jean-Claude Tardif

Vesna Sossi

Michael Noseworthy

Katherine Zukotynski

Mukul Sharma

Philip Barber

Aravind Ganesh

Alexander Thiel

Vincent Gaudet

Julie Ottoy

Lorne Zinman

Mariana Bento

Tolulope Sajobi

Howard Chertkow

Alan Wilman

Robert Laforce

Simon Graham

Elise Fear

Shelagh Coutts

Walter Swardfager

Catherine Lebel

Stephen Strother

Simon Duchesne

Helen Carlson

Andreas Wielgosz

Amanpreet Badhwar

Jay Riva-Cambrin

Mayank Goyal

Andrew Demchuk

MedShapeNet - a large-scale dataset of 3D medical shapes for computer vision.

Signature White Matter Hyperintensity Locations Associated With Vascular Risk Factors Derived From 15 653 Individuals.