Faculty profile

Simon Duchesne

ResearcherRadiology and Nuclear MedicineUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.

Simon Duchesne

Researcher

Radiology and Nuclear Medicine

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
40 publications in the last five years, latest in 2026.
Senior (last) author on 19 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (7 CIHR, 3 NSERC), most recently in 2025.
Supervised 2 trainees who won CIHR awards, most recently in 2020.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

114

Publications

151

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Alzheimer'S Disease Brain Health Cardiovascular And Metabolic Health In Silicon Intervention Testing Mathematical Models Prevention Risk Factors Sex And Gender

Latest papers

Detecting dynamic pathways and risk indicators of resilience, vulnerability and stability in normally aging females and males: Integrating data-driven longitudinal and machine learning analyses.
Neurobiology of aging · 2026
Investigating Physical Exercise and Cognitive Training Effects on Cognition and Brain Health in Men and Women with Heart Failure: The ReCARDIO Trial.
CJC open · 2026
A scoping review of computational models on human glucose cerebral metabolism.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026 · senior author

All 114 publications

Latest funding

Leveraging CLSA Data Through Mechanistic Modeling of Contextualized Brain Health Trajectories
CIHR · 2025 · Nominated PI
$70,000
Investigating Metabolic, Brain, and Cognitive Alterations through Bariatric Surgery: Key Determinants and Prospective Outcomes
CIHR · 2025 · Co-investigator
$1,178,100
Preclinical safety, pharmacokinetics, pharmacodynamics, and efficiency of microRNA oligonucleotides for Alzheimer's disease
CIHR · 2021 · Co-investigator
$1,150,180

All 16 grants and awards

114 publications.

Detecting dynamic pathways and risk indicators of resilience, vulnerability and stability in normally aging females and males: Integrating data-driven longitudinal and machine learning analyses.

Drouin SM, Potvin O, Fah H, Anstey KJ, Masellis M, Duchesne S, Dixon RA, Alzheimer’s Disease Neuroimaging Initiative

Neurobiology of aging2026

DOI: 10.1016/j.neurobiolaging.2026.09.002 PMID: 42731569

Investigating Physical Exercise and Cognitive Training Effects on Cognition and Brain Health in Men and Women with Heart Failure: The ReCARDIO Trial.

Bherer L, Besnier F, Gagnon C, Vrinceanu T, Vincent T, Mohammadi H, Gauthier C, Duquesne C, Blanchette CA, Bérubé B, Said SN, Iglesies-Grau J, L'Allier P, Boulet J, Nigam A, Dionne V, Benhalima H, Dubé MP, Duchesne S, Belleville S, Brassard P, Gagnon D, Lesage F, Gayda M, Soucy JP, Bouabdallaoui N, Liu-Ambrose T, Barha C, Poirier J, Éric Thorin, Vu M, Tournoux F, Vitali P, O'Meara E, Racine N, Rouleau JL

CJC open2026

DOI: 10.1016/j.cjco.2026.02.014 PMID: 42327429

A scoping review of computational models on human glucose cerebral metabolism.

Fereydouni-Forouzandeh P, Michaud A, Doyon N, Duchesne S

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2026Senior author

DOI: 10.1177/0271678x261465840 PMID: 42339824

Sensitivity analysis of a mathematical model of Alzheimer's disease progression unveils important causal pathways.

Moravveji S, Sadia H, Doyon N, Duchesne S

Frontiers in neuroinformatics2025Senior author

DOI: 10.3389/fninf.2025.1590968 PMID: 40771353

Investigating the effects of a randomized, double-blinded aerobic, resistance, and cognitive training clinical trial on neurocognitive function in older adults with cardiovascular risk factors: the ACTIONcardioRisk protocol.

Bherer L, Vrinceanu T, Dupuy EG, Gayda M, Vincent T, Magnan PO, Mohammadi H, Gauthier C, Gagnon C, Duchesne S, Erickson KI, Gagnon D, Lesage F, Lupien S, Poirier J, Dubé MP, Thorin É, Juneau M, Breton J, Belleville S, Ferland G, Gaudreau-Majeau F, Blanchette CA, Vitali P, Nigam A

Frontiers in aging neuroscience2025

DOI: 10.3389/fnagi.2025.1605128 PMID: 40625372

Commonalities in cortical neurodegeneration between type 2 diabetes and Alzheimer's disease.

Motaghi M, Potvin O, Duchesne S, Alzheimer's Disease Neuroimaging Initiative

Journal of Alzheimer's disease : JAD2025Senior author

DOI: 10.1177/13872877251365671 PMID: 40785308

A brain health framework with application to the study of neurodegeneration.

Duchesne S, Potvin O, Hudon C, Bocti C

Journal of Alzheimer's disease : JAD2025First author

DOI: 10.1177/13872877251364867 PMID: 40760852

Predicting Episodes of Hypovigilance in Intensive Care Units Using Routine Physiological Parameters and Artificial Intelligence: Derivation Study.

Giguère R, Niaussat V, Noël-Hunter M, Witteman W, Paul TS, Marois A, Després P, Duchesne S, Archambault PM

JMIR AI2025

DOI: 10.2196/60885 PMID: 40864885

Enhanced Detection of Age-Related and Cognitive Declines Using Automated Hippocampal-To-Ventricle Ratio in Alzheimer's Patients.

Fernandez-Lozano S, Fonov V, Schoemaker D, Pruessner J, Potvin O, Duchesne S, Collins DL, Alzheimer's Disease Neuroimaging Initiative

Human brain mapping2025

DOI: 10.1002/hbm.70265 PMID: 40747973

Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research

Smith EE, Phillips NA, Feldman HH, Borrie M, Ganesh A, Henri-Bhargava A, Desmarais P, Frank A, Badhwar A, Barlow L

The journal of prevention of Alzheimer's disease202537 citations

DOI: 10.1016/j.tjpad.2025.100068

Leveraging CLSA Data Through Mechanistic Modeling of Contextualized Brain Health Trajectories

Nominated PICIHR2025Catalyst Grant: Analysis of CLSA Data

Principal investigators: Duchesne, Simon

Keywords: Brain Health; Cardiovascular And Metabolic Health; In Silicon Intervention Testing; Mathematical Models; Prevention; Risk Factors; Sex And Gender; Socio-Environmental Determinants

$70,000

Investigating Metabolic, Brain, and Cognitive Alterations through Bariatric Surgery: Key Determinants and Prospective Outcomes

Co-investigatorCIHR2025Project Grant

Principal investigators: Michaud, Andréanne; Dadar, Mahsa; Zeighami, Yashar

Keywords: Bariatric Surgery; Brain Health; Cognitive Function; Lifestyle Factors; Metabolic Health; Obesity; Prospective Study

$1,178,100

Preclinical safety, pharmacokinetics, pharmacodynamics, and efficiency of microRNA oligonucleotides for Alzheimer's disease

Co-investigatorCIHR2021Project Grant

Principal investigators: Hébert, Sébastien

Keywords: Cognition; Gene Therapy; Intrathecal; Microrna; Mouse; Neurodegenerative Diseases; Oligonucleotide; Pharmacokinetics; Primate; Toxicology

$1,150,180

Computational neuroscience modelling of cognitively healthy aging and Alzheimer's disease

Nominated PICIHR2021Project Grant

Principal investigators: Duchesne, Simon

Keywords: Aging; Alzheimer'S Disease; Computational Neuroscience; Mathematical Model; Microscale; Model Validation; Neurometabolism; Neuropathology; Neurovascular Unit; Non-Pharmacological Interventions

$501,076

Radio-histological staging of cerebrovascular disease in the aging brain: Insight into vascular contribution to cognitive impairment

SupervisorCIHR2020Canada Graduate Scholarships - Michael Smith Foreign Study Supplements

Principal investigators: Dallaire-Théroux, Caroline

Keywords: Aging; Brain; Cerebrovascular Disease; Neurodegenerative Conditions; Vascular

$6,000

COVID-19 - Alliance - BATMAN: Body Accurate Temperature Measurement Approach by Non-Contact infrared_x000d_ _x000d_ _x000d_ _x000d_ _x000d_ _x000d_ _x000d_

Co-investigatorNSERC2020Alliance Grants

Principal investigators: Maldague, Xavier

$50,000

Brain Health Model and Simulator

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Duchesne, Simon

$115,000

An integrative brain health model for the individual prediction of cognitive decline

Nominated PICIHR2018Project Grant

Principal investigators: Duchesne, Simon

Keywords: Alzheimer'S Disease; Brain Health; Cerebrovascular Integrity; Integrative Model; Metabolic Integrity; Mild Cognitive Impairment; Myelin Integrity; Neuroimaging Proxies; Neuronal Integrity; Systemic Variables

$489,600

Ensuring mission success and optimal aging: disentangling the impact of simulated microgravity on brain health

Nominated PICIHR2018Operating Grant: Understanding the Health Impact of Inactivity

Principal investigators: Duchesne, Simon

Keywords: Alzheimer'S Disease; Behavior; Brain Health; Cognition; Microgravity; Mri; Neurodegeneration; Non-Pharmacological Counter-Measures; Teleadministration

$199,868

Corrélation radio-pathologique dans la maladie d'Alzheimer : Identification précoce par IRM pré-mortem

SupervisorCIHR2017Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Dallaire-Théroux, Caroline

Keywords: Diagnostic Précoce; Démences; Histologie; Imagerie Par Résonance Magnétique (Irm); Maladie D'Alzheimer; Neuroimagerie; Neuropathologie; Neurosciences; Vieillissement; Volumétrie

$105,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Alzheimer'S Disease Dear Professor Duchesne, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Detecting dynamic pathways and risk indicators of resilience, vulnerability and stability in normally aging females and males: Integrating data-driven longitudinal and machine learning analyses." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Leveraging CLSA Data Through Mechanistic Modeling of Contextualized Brain Health Trajectories" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Something wrong or missing on this profile? Suggest a correction

Simon Duchesne

Research

Latest papers

Latest funding

Detecting dynamic pathways and risk indicators of resilience, vulnerability and stability in normally aging females and males: Integrating data-driven longitudinal and machine learning analyses.

Investigating Physical Exercise and Cognitive Training Effects on Cognition and Brain Health in Men and Women with Heart Failure: The ReCARDIO Trial.

A scoping review of computational models on human glucose cerebral metabolism.

Sensitivity analysis of a mathematical model of Alzheimer's disease progression unveils important causal pathways.

Investigating the effects of a randomized, double-blinded aerobic, resistance, and cognitive training clinical trial on neurocognitive function in older adults with cardiovascular risk factors: the ACTIONcardioRisk protocol.

Commonalities in cortical neurodegeneration between type 2 diabetes and Alzheimer's disease.

A brain health framework with application to the study of neurodegeneration.

Predicting Episodes of Hypovigilance in Intensive Care Units Using Routine Physiological Parameters and Artificial Intelligence: Derivation Study.

Enhanced Detection of Age-Related and Cognitive Declines Using Automated Hippocampal-To-Ventricle Ratio in Alzheimer's Patients.

Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research

COVID-19 - Alliance - BATMAN: Body Accurate Temperature Measurement Approach by Non-Contact infrared_x000d_ _x000d_ _x000d_ _x000d_ _x000d_ _x000d_ _x000d_

Brain Health Model and Simulator

Frequent collaborators

Mahsa Dadar

Mario Masellis

Mahsa Dadar

Serge Gauthier

Sylvie Belleville

Louis Bherer

Sylvie Belleville

Robert Bartha

Serge Gauthier

Louis Bherer

Louis Bherer

Judes Poirier

Robert Laforce

Manuel Montero Odasso

Pierre Bellec

Michael Borrie

Pierre Bellec

Teresa Liu-Ambrose

Amanpreet Badhwar

Natalie Phillips

Pedro Rosa-Neto

Saija Kontulainen

Martin Lepage

Marie-Jeanne Kergoat

Melissa Andrew

Linda Lee

Alan Evans

Frédéric Calon

Guylaine Ferland

Ian Mackenzie

Mukul Sharma