Roger Thompson, University of Calgary

Research

Stroke Excitotoxicity Pannexin Nmda Receptor Electrophysiology Biomarkers Cell Death Synaptic Plasticity

Latest papers

TRPV1 promotes opioid analgesia during inflammation.
Science signaling · 2019
Protection against recurrent stroke with resveratrol: endothelial protection.
PloS one · 2012

All 2 publications

Latest funding

Diverse functionality of pannexin-1 mediated by multiple gating mechanisms
NSERC · 2024 · Principal investigator
$47,000
Health Research Training to Address Vascular Contributions to Cognitive Decline: the Vascular Training (VAST) Platform
CIHR · 2021 · Co-investigator
$2,380,292
Capturing the dynamics of inter-organelle associations
NSERC · 2020 · Co-investigator
$119,338

All 12 grants and awards

2 publications.

01

TRPV1 promotes opioid analgesia during inflammation.

Basso L, Aboushousha R, Fan CY, Iftinca M, Melo H, Flynn R, Agosti F, Hollenberg MD, Thompson R, Bourinet E, Trang T, Altier C

Science signaling2019

DOI: 10.1126/scisignal.aav0711 PMID: 30940767

02

Protection against recurrent stroke with resveratrol: endothelial protection.

Clark D, Tuor UI, Thompson R, Institoris A, Kulynych A, Zhang X, Kinniburgh DW, Bari F, Busija DW, Barber PA

PloS one2012

DOI: 10.1371/journal.pone.0047792 PMID: 23082218

Diverse functionality of pannexin-1 mediated by multiple gating mechanisms

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Thompson, Roger

Keywords: pannexin; purinergic; endocannabinoid; patch clamp; imaging; biophysics; synaptic activity

$47,000

Health Research Training to Address Vascular Contributions to Cognitive Decline: the Vascular Training (VAST) Platform

Co-investigatorCIHR2021Tr. Grant: Health Research Training Platform - Vascular Cognitive Impairment

Principal investigators: Smith, Eric E; Badhwar, Amanpreet; Mazerolle, Erin L; Stefanovic, Bojana

Keywords: Vascular Cognitive Impairment

$2,380,292

Capturing the dynamics of inter-organelle associations

Co-investigatorNSERC2020Research Tools and Instruments

Principal investigators: Turner, Raymond

$119,338

Mechanisms of suppression of excitotoxicity by endogenous amyloid beta

Nominated PICIHR2019Project Grant

Principal investigators: Thompson, Roger J

Keywords: Amyloid; Excitotoxicity; Pannexin; Stroke

$1,181,925

Neurovascular damage determines disease pathophysiology: source of new biomarkers

Nominated PICIHR2019Team Grant: NEURON

Principal investigators: Thompson, Roger J

Keywords: Biomarkers; Cell Death; Synaptic Plasticity; Traumatic Brain Injurt; Young Animals

$225,000

Pannexin-1 Opening in Neurons: Mechanisms of Intrinsic Neuroprotection

Nominated PICIHR2019Project Grant

Principal investigators: Thompson, Roger J

Keywords: 2 Photon Imaging; Excitotoxicity; Metabrotropic Nmda Receptor; Molecular Biology; Nmda Receptor; Pannexin-1; Patch-Clamp; Src Kinase; Stroke

$1,032,750

Pannexin-1 channels as facilitators of anandamide membrane transpor

Principal investigatorNSERC2018Discovery Grants Program - Accelerator Supplements

Principal investigators: Thompson, Roger

$120,000

Pannexin-1 channels as facilitators of anandamide membrane transport

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Thompson, Roger

$300,000

Targeting pannexin-1 channels to modulate neuroinflammation during reperfusion after stroke

Nominated PICIHR2016Project Grant

Principal investigators: Thompson, Roger J

Keywords: Electrophysiology; Flow Cytometry; Immune Cell; Inflammasome; Inflammation; Multiphoton Microscopy; Pannexin; Stroke

$100,000

Pannexin-1 Channel Opening in Neurons

Nominated PICIHR2014Operating Grant

Principal investigators: Thompson, Roger J

Keywords: Behavioural Outcomes; Electrophysiology; Excitotoxicity; Ischemia; Long Term Depression; Nmda Receptor; Pannexin; Protein-Protein Interactions; Stroke; Two Photon Imaging

$882,662

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Cell Biology and Anatomy
Physiology and Pharmacology
Other

Co-authors at University of Calgary, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Christophe Altier

Physiology and Pharmacology

1 shared papers, latest 2019

Tuan Trang

Faculty

1 shared papers, latest 2019

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2024

Subject: Prospective PhD student: Stroke Dear Professor Thompson, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "TRPV1 promotes opioid analgesia during inflammation." (2019), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Diverse functionality of pannexin-1 mediated by multiple gating mechanisms" (2024), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]