Dipankar Sen, Simon Fraser University

Latest papers

Short DNAzymes for Efficient Catalysis of "Click" Reactions in Solution and on Surface.
Langmuir : the ACS journal of surfaces and colloids · 2024
Unusual Paradigm for DNA-DNA Recognition and Binding: "Socket-Plug" Complementarity.
Journal of the American Chemical Society · 2023 · senior author
A Long and Reversibly Self-Assembling 1D DNA Nanostructure Built from Triplex and Quadruplex Hybrid Tiles.
Angewandte Chemie (International ed. in English) · 2021 · senior author

All 47 publications

Latest funding

Diagnostic aptamer selection for the beetle pheromone verbenone and its derivatives
NSERC · 2019 · Principal investigator
$25,000
Enhanced 2D Imaging for Gels and Membranes
NSERC · 2018 · Co-investigator
$147,226
Catalytic nucleic acids that highlight surprising fundamental properties of DNA and RNA
NSERC · 2017 · Principal investigator
$426,000

All 34 grants and awards

47 publications.

01

Short DNAzymes for Efficient Catalysis of "Click" Reactions in Solution and on Surface.

Leung TY, Qi L, Liu K, Sen D, Yu HZ

Langmuir : the ACS journal of surfaces and colloids2024

DOI: 10.1021/acs.langmuir.4c02314 PMID: 39305250

02

Unusual Paradigm for DNA-DNA Recognition and Binding: "Socket-Plug" Complementarity.

Yutong Huang F, Kumar Lat P, Sen D

Journal of the American Chemical Society2023Senior author

DOI: 10.1021/jacs.2c12514 PMID: 36706227

03

A Long and Reversibly Self-Assembling 1D DNA Nanostructure Built from Triplex and Quadruplex Hybrid Tiles.

Lat PK, Schultz CW, Yu HZ, Sen D

Angewandte Chemie (International ed. in English)2021Senior author

DOI: 10.1002/anie.202016668 PMID: 33580565

04

A heme•DNAzyme activated by hydrogen peroxide catalytically oxidizes thioethers by direct oxygen atom transfer rather than by a Compound I-like intermediate.

Shumayrikh NM, Warren JJ, Bennet AJ, Sen D

Nucleic acids research2021Senior author

DOI: 10.1093/nar/gkab007 PMID: 33476369

05

CLICK-17, a DNA enzyme that harnesses ultra-low concentrations of either Cu+ or Cu2+ to catalyze the azide-alkyne 'click' reaction in water.

Liu K, Lat PK, Yu HZ, Sen D

Nucleic acids research2020Senior author

DOI: 10.1093/nar/gkaa502 PMID: 32520335

06

High specificity and tight spatial restriction of self-biotinylation by DNA and RNA G-Quadruplexes complexed in vitro and in vivo with Heme.

Lat PK, Liu K, Kumar DN, Wong KKL, Verheyen EM, Sen D

Nucleic acids research2020Senior author

DOI: 10.1093/nar/gkaa281 PMID: 32329781

07

DNA G-Quadruplexes Activate Heme for Robust Catalysis of Carbene Transfer Reactions.

Ibrahim H, Mulyk P, Sen D

ACS omega2019Senior author

DOI: 10.1021/acsomega.9b02305 PMID: 31552375

08

DNA Quadruple Helices in Nanotechnology.

Mergny JL, Sen D

Chemical reviews2019Senior author

DOI: 10.1021/acs.chemrev.8b00629 PMID: 30605316

09

Heme•G-Quadruplex DNAzymes: Conditions for Maximizing Their Peroxidase Activity.

Shumayrikh N, Sen D

Methods in molecular biology (Clifton, N.J.)2019Senior author

DOI: 10.1007/978-1-4939-9666-7_22 PMID: 31444762

10

Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma.

Arthur SE, Jiang A, Grande BM, Alcaide M, Cojocaru R, Rushton CK, Mottok A, Hilton LK, Lat PK, Zhao EY, Culibrk L, Ennishi D, Jessa S, Chong L, Thomas N, Pararajalingam P, Meissner B, Boyle M, Davidson J, Bushell KR, Lai D, Farinha P, Slack GW, Morin GB, Shah S, Sen D, Jones SJM, Mungall AJ, Gascoyne RD, Audas TE, Unrau P, Marra MA, Connors JM, Steidl C, Scott DW, Morin RD

Nature communications2018

DOI: 10.1038/s41467-018-06354-3 PMID: 30275490

Diagnostic aptamer selection for the beetle pheromone verbenone and its derivatives

Principal investigatorNSERC2019Engage Grants Program

Principal investigators: Sen, Dipankar

$25,000

Enhanced 2D Imaging for Gels and Membranes

Co-investigatorNSERC2018Research Tools and Instruments

Principal investigators: Audas, Timothy

$147,226

Catalytic nucleic acids that highlight surprising fundamental properties of DNA and RNA

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Sen, Dipankar

$426,000

UV-visible spectrophotometer for specific biochemical utility

Principal investigatorNSERC2016Research Tools and Instruments

Principal investigators: Sen, Dipankar

$62,081

Aptamer-based electrochemical sensor for ochratoxin

Principal investigatorNSERC2015Engage Grants Program

Principal investigators: Sen, Dipankar

$25,000

Instrumentation for nanosecond time-resolved transient absorption and luminescence: from protein dynamics to photovoltaics

Co-investigatorNSERC2014Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Warren, Jeffrey

$149,809

CD Spectrophotometer for Biological Studies

Co-investigatorNSERC2014Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Bennet, Andrew

$148,351

Multi-purpose imager (Typhoon FLA 9500)

Co-investigatorNSERC2013Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Cornell, Rosemary

$40,000

Ribozymes and DNAzymes-- ancient catalytic activities for modern biomedical and other utility

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Sen, Dipankar

$355,000

Ribozymes and DNAzymes-- ancient catalytic activities for modern biomedical and other utility

Principal investigatorNSERC2012Discovery Grants Program - Accelerator Supplements

Principal investigators: Sen, Dipankar

$120,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Molecular Biology and Biochemistry
Department of Chemistry
Experimental Therapeutics
Institute of Molecular Biology and Biochemistry
Chemistry
Other

Co-authors at Simon Fraser University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Hua-Zhong Yu

Department of Chemistry

12 shared papers, latest 2024

Christian Steidl

Experimental Therapeutics

1 shared papers, latest 2018

Sohrab Shah

Faculty

1 shared papers, latest 2018

Wesley Zandberg

Chemistry

1 shared papers, latest 2010

Peter Unrau

Institute of Molecular Biology and Biochemistry

1 shared papers, latest 2018

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2019

Subject: Prospective PhD student Dear Professor Sen, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Short DNAzymes for Efficient Catalysis of "Click" Reactions in Solution and on Surface." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Diagnostic aptamer selection for the beetle pheromone verbenone and its derivatives" (2019), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Dipankar Sen

Latest papers

Latest funding

Short DNAzymes for Efficient Catalysis of "Click" Reactions in Solution and on Surface.

Unusual Paradigm for DNA-DNA Recognition and Binding: "Socket-Plug" Complementarity.

A Long and Reversibly Self-Assembling 1D DNA Nanostructure Built from Triplex and Quadruplex Hybrid Tiles.

A heme&#x2022;DNAzyme activated by hydrogen peroxide catalytically oxidizes thioethers by direct oxygen atom transfer rather than by a Compound I-like intermediate.

CLICK-17, a DNA enzyme that harnesses ultra-low concentrations of either Cu+ or Cu2+ to catalyze the azide-alkyne 'click' reaction in water.

High specificity and tight spatial restriction of self-biotinylation by DNA and RNA G-Quadruplexes complexed in vitro and in vivo with Heme.

DNA G-Quadruplexes Activate Heme for Robust Catalysis of Carbene Transfer Reactions.

DNA Quadruple Helices in Nanotechnology.

Heme&#x2022;G-Quadruplex DNAzymes: Conditions for Maximizing Their Peroxidase Activity.

Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma.

Diagnostic aptamer selection for the beetle pheromone verbenone and its derivatives

Enhanced 2D Imaging for Gels and Membranes

Catalytic nucleic acids that highlight surprising fundamental properties of DNA and RNA

UV-visible spectrophotometer for specific biochemical utility

Aptamer-based electrochemical sensor for ochratoxin

Instrumentation for nanosecond time-resolved transient absorption and luminescence: from protein dynamics to photovoltaics

CD Spectrophotometer for Biological Studies

Multi-purpose imager (Typhoon FLA 9500)

Ribozymes and DNAzymes-- ancient catalytic activities for modern biomedical and other utility

Ribozymes and DNAzymes-- ancient catalytic activities for modern biomedical and other utility

Frequent collaborators

Hua-Zhong Yu

Christian Steidl

Sohrab Shah

Wesley Zandberg

Peter Unrau

A heme•DNAzyme activated by hydrogen peroxide catalytically oxidizes thioethers by direct oxygen atom transfer rather than by a Compound I-like intermediate.

Heme•G-Quadruplex DNAzymes: Conditions for Maximizing Their Peroxidase Activity.