Haolun Shi, Simon Fraser University

Research

Functional data analysis Functional principal component analysis Imaging data Likelihood Missing data Robust Regression Smoothing Spline

Latest papers

Oral Nirmatrelvir-Ritonavir for Covid-19 in Higher-Risk Outpatients.
The New England journal of medicine · 2026
A statistical evaluation of decision-making methods and the efficiency of Bayesian multi-arm multi-stage trials.
Clinical trials (London, England) · 2026
Canadian Adaptive Platform Trial of Treatments for COVID in Community Settings (CanTreatCOVID): protocol for a randomised controlled adaptive platform trial of treatments for acute SARS-CoV-2 infection in community settings
BMJ Open · 2025

All 24 publications

Latest funding

Analysis and Modeling of Functional Data in Biostatistics
NSERC · 2021 · Principal investigator
$12,500
Analysis and Modeling of Functional Data in Biostatistics
NSERC · 2021 · Principal investigator
$72,000

All 2 grants and awards

24 publications.

01

Oral Nirmatrelvir-Ritonavir for Covid-19 in Higher-Risk Outpatients.

Butler CC, Pinto AD, Harris V, Holmes J, Rahman NM, Cureton L, Hayward G, Richards DB, Lowe DM, Standing JF, Breuer J, Hood K, Png ME, Petrou S, Dorward J, Patel MG, Thomas NPB, Evans P, Hart ND, Jani BD, Hosseini B, Murthy S, McBrien K, Condon A, McDonald EG, Daley P, Greiver M, da Costa BR, Selby P, Jüni P, Lee TC, Shi H, Detry MA, Saunders CT, Fitzgerald M, Berry NS, Saville BR, Khoo SH, Nguyen-Van-Tam JS, Hobbs FDR, Yu LM, Little P, PANORAMIC Trial and CanTreatCOVID Trial Collaborative Groups

The New England journal of medicine2026

DOI: 10.1056/nejmoa2502457 PMID: 42019019

02

A statistical evaluation of decision-making methods and the efficiency of Bayesian multi-arm multi-stage trials.

McGrory A, Shi H, Heath A

Clinical trials (London, England)2026

DOI: 10.1177/17407745261453566 PMID: 42358099

03

Canadian Adaptive Platform Trial of Treatments for COVID in Community Settings (CanTreatCOVID): protocol for a randomised controlled adaptive platform trial of treatments for acute SARS-CoV-2 infection in community settings

Hosseini B, Condon A, da Costa BR, Daley P, Greiver M, Jüni P, Lee TC, McBrien K, McDonald EG, Murthy S

BMJ Open20256 citations

DOI: 10.1136/bmjopen-2024-097134

04

Target Aggregate Data Adjustment Method for Transportability Analysis Utilizing Summary-Level Data From the Target Population.

Yan Y, Vuong Q, Metcalfe RK, Guan T, Shi H, Park JJH

Pharmaceutical statistics2025

DOI: 10.1002/pst.70029 PMID: 40765487

05

A Generalized Phase I/II Dose Optimization Trial Design With Multi-Categorical and Multi-Graded Outcomes.

Yan Y, Lin R, Guan T, Shi H, Lin X

Statistics in medicine2025

DOI: 10.1002/sim.70049 PMID: 40213898

06

Supervised Functional Principal Component Analysis Under the Mixture Cure Rate Model: An Application to Alzheimer'S Disease.

Feng J, Shi H, Ma D, Faisal Beg M, Cao J

Statistics in medicine2025

DOI: 10.1002/sim.10324 PMID: 39853780

07

Penalized functional regression using R package PFLR.

Cameron R, Guan T, Shi H, Lin Z

Journal of applied statistics2025

DOI: 10.1080/02664763.2025.2457011 PMID: 40951834

08

A Latent-Class Model for Time-To-Event Outcomes and High-Dimensional Imaging Data.

Feng J, Shi H, Da M, Beg MF, Cao J

Statistics in medicine2025

DOI: 10.1002/sim.70186 PMID: 40662861

09

Identification of Regions of Interest in Neuroimaging Data With Irregular Boundary Based on Semiparametric Transformation Models and Interval-Censored Outcomes.

Lee CY, Shi H, Ma D, Beg MF, Cao J

Statistics in medicine2025

DOI: 10.1002/sim.70309 PMID: 41201240

10

Drift Parameter Based Sample Size Determination in Multi-Stage Bayesian Randomized Clinical Trials.

Han Y, Shi H, Cao J, Lin R

Pharmaceutical statistics2025

DOI: 10.1002/pst.70037 PMID: 40810309

Analysis and Modeling of Functional Data in Biostatistics

Principal investigatorNSERC2021Discovery Launch Supplement

Principal investigators: Shi, Haolun

$12,500

Analysis and Modeling of Functional Data in Biostatistics

Principal investigatorNSERC2021Discovery Grants Program - Individual

Principal investigators: Shi, Haolun

Keywords: functional data analysis; functional principal component analysis; robust regression; likelihood; missing data; imaging data; smoothing spline

$72,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Peter Selby and Aisha Lofters: 10 shared papers
Jiguo Cao and Liangliang Wang: 10 shared papers
Jiguo Cao and Haolun Shi: 10 shared papers
Jean-Eric Tarride and Derelie A Mangin: 9 shared papers
Derelie A Mangin and Alexander Singer: 7 shared papers
Derelie A Mangin and Michelle Greiver: 6 shared papers
Peter Selby and Kerry McBrien: 6 shared papers
Alexander Singer and Michelle Greiver: 6 shared papers
Srinivas Murthy and Peter Daley: 6 shared papers
Kerry McBrien and Aisha Lofters: 5 shared papers
Catherine Hudon and Alexander Singer: 4 shared papers
Peter Selby and Michelle Greiver: 4 shared papers
Peter Selby and Abhimanyu Sud: 3 shared papers
Peter Selby and Srinivas Murthy: 3 shared papers
Peter Selby and Peter Daley: 3 shared papers
Kerry McBrien and Srinivas Murthy: 3 shared papers
Kerry McBrien and Peter Daley: 3 shared papers
Aisha Lofters and Jennifer Rayner: 3 shared papers
Abhimanyu Sud and Michelle Greiver: 3 shared papers
Haolun Shi and Tianyu Guan: 3 shared papers
Derelie A Mangin and Jennifer Rayner: 2 shared papers
Catherine Hudon and Srinivas Murthy: 2 shared papers
Peter Selby and Haolun Shi: 2 shared papers
Brendan Barrett and Peter Daley: 2 shared papers
Kerry McBrien and Haolun Shi: 2 shared papers
Aisha Lofters and Jennifer Hulme: 2 shared papers
Srinivas Murthy and Haolun Shi: 2 shared papers
David Barber and Michelle Greiver: 2 shared papers
Michelle Greiver and Haolun Shi: 2 shared papers
Peter Daley and Haolun Shi: 2 shared papers
Liangliang Wang and Haolun Shi: 2 shared papers
Jean-Eric Tarride and Catherine Hudon: 1 shared paper
Jean-Eric Tarride and Peter Selby: 1 shared paper
Jean-Eric Tarride and Jennifer Isenor: 1 shared paper
Jean-Eric Tarride and Brendan Barrett: 1 shared paper
Jean-Eric Tarride and Abhimanyu Sud: 1 shared paper
Jean-Eric Tarride and David Barber: 1 shared paper
Jean-Eric Tarride and Brianne Wood: 1 shared paper
Jean-Eric Tarride and Jennifer Hulme: 1 shared paper
Jean-Eric Tarride and Daniel Warshafsky: 1 shared paper
Jean-Eric Tarride and Jennifer Rayner: 1 shared paper
Jean-Eric Tarride and Haolun Shi: 1 shared paper
Derelie A Mangin and Jennifer Isenor: 1 shared paper
Derelie A Mangin and Brendan Barrett: 1 shared paper
Derelie A Mangin and David Barber: 1 shared paper
Derelie A Mangin and Brianne Wood: 1 shared paper
Derelie A Mangin and Jennifer Hulme: 1 shared paper
Derelie A Mangin and Daniel Warshafsky: 1 shared paper
Derelie A Mangin and Haolun Shi: 1 shared paper
Joanne Matsubara and Haolun Shi: 1 shared paper
Catherine Hudon and Jennifer Isenor: 1 shared paper
Catherine Hudon and Brianne Wood: 1 shared paper
Catherine Hudon and Daniel Warshafsky: 1 shared paper
Catherine Hudon and Haolun Shi: 1 shared paper
Jennifer Isenor and Haolun Shi: 1 shared paper
Brendan Barrett and Haolun Shi: 1 shared paper
Aisha Lofters and Haolun Shi: 1 shared paper
Abhimanyu Sud and Haolun Shi: 1 shared paper
Alexander Singer and Haolun Shi: 1 shared paper
Srinivas Murthy and Anna Heath: 1 shared paper
David Barber and Haolun Shi: 1 shared paper
Anna Heath and Haolun Shi: 1 shared paper
Brianne Wood and Haolun Shi: 1 shared paper
Jennifer Hulme and Haolun Shi: 1 shared paper
Daniel Warshafsky and Haolun Shi: 1 shared paper
Jennifer Rayner and Haolun Shi: 1 shared paper
Jiguo Cao and Jian Pei: 1 shared paper
Jian Pei and Haolun Shi: 1 shared paper

Department of Family and Community Medicine
Community Health Sciences
Statistics and Actuarial Science
Department of Statistics and Actuarial Science,
MATHEMATICS AND STATISTICS
Statistical and Actuarial Sciences
Infectious Diseases/Internal Medicine
Other

1 shared papers, latest 2025

Rae Spiwak

Surgery

1 shared papers, latest 2025

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2021

Subject: Prospective PhD student: Functional data analysis Dear Professor Shi, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Oral Nirmatrelvir-Ritonavir for Covid-19 in Higher-Risk Outpatients." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Analysis and Modeling of Functional Data in Biostatistics" (2021), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]