Nansheng Chen, Simon Fraser University

Research

alternative splicing exon gene intron model organism operon spatial temporal

Latest papers

Comparative analysis of mitochondrial genomes of Chaetoceros species.
Journal of phycology · 2025 · senior author
Intragenomic variations of the harmful algal bloom species Phaeocystis globosa through single-strain metabarcoding analysis.
Marine pollution bulletin · 2024 · senior author
Chromosome-scale genome assembly reveals insights into the evolution and ecology of the harmful algal bloom species Phaeocystis globosa Scherffel.
iScience · 2024 · first author

All 86 publications

Latest funding

Dynamic splicing and trans-splicing in the model organism Caenorhabditis elegans
NSERC · 2020 · Principal investigator
$192,000
Training Program in High-Dimensional Bioinformatics (HDB)
NSERC · 2015 · Co-investigator
$1,650,000
Digital polymerase chain reaction (PCR) and high-capacity multiplex PCR for next-generation sequencing
NSERC · 2015 · Co-investigator
$126,802

All 12 grants and awards

86 publications.

01

Comparative analysis of mitochondrial genomes of Chaetoceros species.

Cui Z, Xu Q, Liu F, Wang J, Chen N

Journal of phycology2025Senior author

DOI: 10.1111/jpy.70017 PMID: 40249850

02

Intragenomic variations of the harmful algal bloom species Phaeocystis globosa through single-strain metabarcoding analysis.

Wang Y, Chen N

Marine pollution bulletin2024Senior author

DOI: 10.1016/j.marpolbul.2024.117180 PMID: 39486199

03

Chromosome-scale genome assembly reveals insights into the evolution and ecology of the harmful algal bloom species Phaeocystis globosa Scherffel.

Chen N, Xu Q, Zhu J, Song H, He L, Liu S, Song X, Yuan Y, Chen Y, Cao X, Yu Z

iScience2024First author

DOI: 10.1016/j.isci.2024.110575 PMID: 39193189

04

Chromosome-level genome assembly of marine diatom Skeletonema tropicum.

Liu S, Chen N

Scientific data2024Senior author

DOI: 10.1038/s41597-024-03238-8 PMID: 38643276

05

Extensive intragenomic variations of the 18S rDNA V4 region in the toxigenic diatom species Pseudo-nitzschia multistriata revealed through high-throughput sequencing.

Wang H, Liu K, He Z, Chen Y, Hu Z, Chen W, Leaw CP, Chen N

Marine pollution bulletin2024Senior author

DOI: 10.1016/j.marpolbul.2024.116198 PMID: 38428045

06

The high molecular diversity in Noctiluca scintillans is dominated by intra-genomic variations revealed by single cell high-throughput sequencing of 18S rDNA V4.

Liu K, Huang X, Ding X, Chen N

Harmful algae2024Senior author

DOI: 10.1016/j.hal.2024.102568 PMID: 38331542

07

Rich diversity and active spatial-temporal dynamics of Thalassiosira species revealed by time-series metabarcoding analysis.

Liu K, Liu S, Cui Z, Zhao Y, Chen N

ISME communications2024Senior author

DOI: 10.1093/ismeco/ycad009 PMID: 38313810

08

Expansion of photoreception-related gene families may drive ecological adaptation of the dominant diatom species Skeletonema marinoi.

Liu S, Xu Q, Chen N

The Science of the total environment2023Senior author

DOI: 10.1016/j.scitotenv.2023.165384 PMID: 37422237

09

Mechanisms of Phaeocystis globosa blooms in the Beibu Gulf revealed by metatranscriptome analysis.

Zhu J, Yu Z, He L, Yuan Y, Wang W, Cao X, Chen N, Wang W, Song X

Harmful algae2023

DOI: 10.1016/j.hal.2023.102407 PMID: 37164562

10

Chromosome-level genome assembly of the Pacific geoduck Panopea generosa reveals major inter- and intrachromosomal rearrangements and substantial expansion of the copine gene family.

Wang J, Xu Q, Chen M, Chen Y, Wang C, Chen N

GigaScience2022Senior author

DOI: 10.1093/gigascience/giad105 PMID: 38116826

Dynamic splicing and trans-splicing in the model organism Caenorhabditis elegans

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Chen, Nansheng

Keywords: transcription; alternative splicing; gene; exon; intron; trans-splicing; operon; spatial; temporal; model organism

$192,000

Training Program in High-Dimensional Bioinformatics (HDB)

Co-investigatorNSERC2015Collaborative Research and Training Experience

Principal investigators: Pavlidis, Paul

$1,650,000

Digital polymerase chain reaction (PCR) and high-capacity multiplex PCR for next-generation sequencing

Co-investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Morin, Ryan

$126,802

Genome architecture dynamics and expression

Principal investigatorNSERC2014Discovery Grants Program - Individual

Principal investigators: Chen, Nansheng

$235,000

Next-generation sequencer for evolutionary genomics

Co-investigatorNSERC2012Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Hart, Michael

$136,083

Cryogenic storage of C. elegans stocks for molecular genetic research

Co-investigatorNSERC2010Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Baillie, David

$21,890

Genome Variations that Drive Increased Fitness in MAD1 and FANCJ-Defective C. elegans

SupervisorCIHR2010Fellowship - Priority Announcement: Fanconi Anemia (SHOPP)

Principal investigators: Tarailo-Graovac, Maja

Keywords: Caenorhabditis Elegans; Cancer; Dog-1/Fancj; Fanconi Anemia; Genetic Interactions; Genome Stability; Genomics/Bioinformatics; Mdf-1/Mad1; Molecular Pathway; Spindle Assembly Checkpoint

$39,375

Equipment for biochemical cell fractionation and analysis

Co-investigatorNSERC2010Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Honda, Barry

$58,868

Symposium in Honor of Dr. Don Riddle's Retirement

Co-investigatorCIHR2010Meetings, Planning and Dissemination Grant: Genetics

Principal investigators: Taubert, Stefan

Keywords: Aging; C. Elegans; Dauer Formation; Genetics; Model Organisms

$5,000

Genome structure variations (SVs) and the origin of novel genes

Nominated PICIHR2009CIHR New Investigator

Principal investigators: Chen, Nansheng J

Keywords: C. Elegans; Genome; Genome Rearrangement; Insertion/Deletion; Novel Gene; Structural Variation

$300,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Molecular Biology and Biochemistry
Computing Science, School of
School of Computing Science
Biological Sciences
Computing Science
Department of Biological Sciences

Co-authors at Simon Fraser University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Ke Wang

Computing Science, School of

3 shared papers, latest 2014

Jian Pei

School of Computing Science

2 shared papers, latest 2009

Ping Liang

Department of Biological Sciences

1 shared papers, latest 2017

Martin Ester

Computing Science

1 shared papers, latest 2010

Harald Hutter

Biological Sciences

1 shared papers, latest 2009

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2020

Subject: Prospective PhD student: alternative splicing Dear Professor Chen, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Comparative analysis of mitochondrial genomes of Chaetoceros species." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Dynamic splicing and trans-splicing in the model organism Caenorhabditis elegans" (2020), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]