Faculty profile

Robert Britton

ResearcherChemistrySimon Fraser University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Simon Fraser University directory, so their courses may be missing. Find their university profile.

Robert Britton

Researcher

Chemistry

Simon Fraser University

Burnaby, British Columbia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
22 publications in the last five years, latest in 2026.
Senior (last) author on 15 recent papers, a sign of leading a research group.
Principal investigator on 17 research grants (17 NSERC), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

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Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

total synthesis synthetic methods asymmetric synthesis C-H functionalization chloroaldehydes directing groups method development natural products

Latest papers

A unified platform for nucleoside analog synthesis.
Science (New York, N.Y.) · 2026 · senior author
The RAvIN Platform: A Noncarbohydrate Platform for Oligonucleotide Synthesis.
Journal of the American Chemical Society · 2026 · senior author
Characterization of Variation in Natural Product Production Under Chemical Elicitation Using Parallel Stable Isotope Labeling.
ACS chemical biology · 2025

All 77 publications

Latest funding

Hands-on high resolution mass spectrometer to support medicinal and materials chemistry
NSERC · 2025 · Co-investigator
$150,000
The Discovery and Development of Photactivatable Leaving Groups for Complex Molecule Synthesis
NSERC · 2024 · Principal investigator
$25,000
Global Center: International Research Center for Enhancing Plant Resilience
NSERC · 2024 · Co-investigator
$421,000

All 27 grants and awards

77 publications.

A unified platform for nucleoside analog synthesis.

Anketell MJ, Fung E, Liu W, Shinde M, He CQ, Ng KWC, Silverman SM, Campeau LC, Pantophlet R, Britton R

Science (New York, N.Y.)2026Senior author

DOI: 10.1126/science.aed6880 PMID: 41785328

The RAvIN Platform: A Noncarbohydrate Platform for Oligonucleotide Synthesis.

Nodwell M, Caballero-García G, Mesa JM, Muilu T, Wilson DM, Arora A, Brooke AJ, Singgh B, Gill M, Tran HM, Silverman SM, Campeau LC, Damha MJ, Britton R

Journal of the American Chemical Society2026Senior author

DOI: 10.1021/jacs.5c21938 PMID: 41850882

Characterization of Variation in Natural Product Production Under Chemical Elicitation Using Parallel Stable Isotope Labeling.

Zaroubi L, Paulo BS, Fung E, Cavanagh H, Britton R, Eustaquio AS, Linington RG

ACS chemical biology2025

DOI: 10.1021/acschembio.5c00346 PMID: 40960132

Rapid Synthesis and Diversification of Thymine-Containing Bridged Nucleic Acids Through Cascade Cyclization Reactions.

Huxley C, Fung E, Singh B, Caballero-García G, Muir G, Silverman SM, Campeau LC, Britton R

Angewandte Chemie (International ed. in English)2025Senior author

DOI: 10.1002/anie.202509964 PMID: 40788029

An Expedient Synthesis of the Antimitotic Natural Products Sarcodictyin and Eleutherobin, and Carbohydrate Analogues.

Driedger D, Fers-Lidou A, Schroeder M, Elisia I, Krystal G, Britton R

Journal of the American Chemical Society2025Senior author

DOI: 10.1021/jacs.5c08176 PMID: 40674682

A gram-scale synthesis of β-L-carbafucose for engineering antibody glycans.

Thota VN, Fers-Lidou A, Nodwell M, McDonagh AW, Gilormini PA, Wang Y, Leung C, Vocadlo DJ, Britton R

Communications chemistry2025Senior author

DOI: 10.1038/s42004-025-01523-0 PMID: 40329042

A sequential esterification-ring closing metathesis-Nozaki-Hiyama-Kishi strategy for constructing a natural product-like library of tetrahydrofuran-containing macrolides.

Driedger D, Wilson DM, Britton R

Chemical science2025Senior author

DOI: 10.1039/d5sc00591d PMID: 40060091

Unmasking the halide effect in diastereoselective Grignard reactions applied to C4´ modified nucleoside synthesis.

Muir G, Caballero-García G, Muilu T, Nodwell M, Park Y, Huxley C, Kaghad A, Silverman SM, Campeau LC, Barroso-Flores J, Britton R

Nature communications2025Senior author

DOI: 10.1038/s41467-025-56895-7 PMID: 39956836

A flexible and scalable synthesis of 4'-thionucleosides.

Lucas C, Fung E, Nodwell M, Silverman S, Singh B, Campeau LC, Britton R

Chemical science2024Senior author

DOI: 10.1039/d4sc05679e PMID: 39611032

Synthesis of the Phormidolide A Macrocycle Supports the Proposed Configurational Reassignment.

Muir G, Paterson I, Lam NYS, Britton R

Organic letters2024Senior author

DOI: 10.1021/acs.orglett.4c03171 PMID: 39332025

Hands-on high resolution mass spectrometer to support medicinal and materials chemistry

Co-investigatorNSERC2025Research Tools and Instruments

Principal investigators: Young, Robert

Keywords: medicinal chemistry; bioinorganic chemistry; chemical biology; materials sciences; drug discovery; drug development; pharmacokinetics; drug metabolism; drug target identification; enzymology

$150,000

The Discovery and Development of Photactivatable Leaving Groups for Complex Molecule Synthesis

Principal investigatorNSERC2024Alliance Grants

Principal investigators: Britton, Robert RA

Keywords: complex molecule synthesis; glycosylation; leaving group; medicinal chemistry; nucleosides; photoacid; photoactivation; rearrangements; synthetic methods; total synthesis

$25,000

Global Center: International Research Center for Enhancing Plant Resilience

Co-investigatorNSERC2024Alliance Grants

Principal investigators: Wilkins, Olivia O

Keywords: bioinformatics; chemical ontologies; chemical synthesis; computational biology; consumer behaviour; metabolomics; natural products; risk perception; spatial transcriptomics

$421,000

Global Center: International Research Center for Enhancing Plant Resilience

Co-investigatorSSHRC2024National Science Foundation Global Centres

Principal investigators: Wilkins, Olivia

Keywords: metabolomics; spatial transcriptomics; bioinformatics; chemical synthesis; risk perception; natural products; consumer behaviour; chemical ontologies; computational biology

$104,000

Rapid Synthesis of Nucleoside Analogues for Drug Discovery

Principal investigatorNSERC2023Alliance Grants

Principal investigators: Britton, Robert RA

Keywords: antivirals; drug disocvery; highthroughput synthesis; locked nucleosides; nucleoside analogues; process research; protides; synthetic methods; thionucleosides; total synthesis

$320,000

Benchtop Walk-Up Time-of-Flight Mass Spectrometer

Co-investigatorNSERC2022Research Tools and Instruments

Principal investigators: Linington, Roger

$146,158

SARS-CoV-2 Rapid Research: Fast track isothermal viral diagnostics

Co-investigatorCIHR2020Operating Grant: COVID-19 - Diagnostics

Principal investigators: Unrau, Peter J; Niikura, Masahiro

Keywords: Covid-19; Flurogenic Rna Mango Aptamers; High Throughput Sequencing; Isothermal Amplification; Medical Testing Device; Nasba; Patient Clinical Samples; Rt-Pcr; Sars-Cov-2; Viral Infection

$516,980

Single turnover covalent chaperones for disease related lysosomal enzymes

Co-investigatorCIHR2020Project Grant

Principal investigators: Bennet, Andrew J

Keywords: Chemical Chaperones; Covalent Inhibitors; Folding; Glucocerebrosidase; Glycoside Hydrolases; Live Cell Imaging; Lysosomal Storage Diseases; Mechanism Based; Parkinson'S; Trafficking

$1,013,626

A Scalable Synthesis of the C14-C23 Fragment of Eribulin_x000d_ _x000d_

Principal investigatorNSERC2020Alliance Grants

Principal investigators: Britton, Robert

$48,000

Critical Acquisition of Modern, Functional Single-crystal X-ray Diffractometer Detector

Co-investigatorNSERC2019Research Tools and Instruments

Principal investigators: Leznoff, Daniel

$149,937

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Robert Britton

Research

Latest papers

Latest funding

A unified platform for nucleoside analog synthesis.

The RAvIN Platform: A Noncarbohydrate Platform for Oligonucleotide Synthesis.

Characterization of Variation in Natural Product Production Under Chemical Elicitation Using Parallel Stable Isotope Labeling.

Rapid Synthesis and Diversification of Thymine-Containing Bridged Nucleic Acids Through Cascade Cyclization Reactions.

An Expedient Synthesis of the Antimitotic Natural Products Sarcodictyin and Eleutherobin, and Carbohydrate Analogues.

A gram-scale synthesis of β-L-carbafucose for engineering antibody glycans.

A sequential esterification-ring closing metathesis-Nozaki-Hiyama-Kishi strategy for constructing a natural product-like library of tetrahydrofuran-containing macrolides.

Unmasking the halide effect in diastereoselective Grignard reactions applied to C4´ modified nucleoside synthesis.

A flexible and scalable synthesis of 4'-thionucleosides.

Synthesis of the Phormidolide A Macrocycle Supports the Proposed Configurational Reassignment.

Hands-on high resolution mass spectrometer to support medicinal and materials chemistry

The Discovery and Development of Photactivatable Leaving Groups for Complex Molecule Synthesis

Global Center: International Research Center for Enhancing Plant Resilience

Global Center: International Research Center for Enhancing Plant Resilience

Rapid Synthesis of Nucleoside Analogues for Drug Discovery

Benchtop Walk-Up Time-of-Flight Mass Spectrometer

SARS-CoV-2 Rapid Research: Fast track isothermal viral diagnostics

Single turnover covalent chaperones for disease related lysosomal enzymes

A Scalable Synthesis of the C14-C23 Fragment of Eribulin_x000d_ _x000d_

Critical Acquisition of Modern, Functional Single-crystal X-ray Diffractometer Detector

Frequent collaborators

Gerhard Gries

Paul Schaffer

Travis Dudding

Ralph Pantophlet

Robert Britton

Research

Latest papers

Latest funding

A unified platform for nucleoside analog synthesis.

The RAvIN Platform: A Noncarbohydrate Platform for Oligonucleotide Synthesis.

Characterization of Variation in Natural Product Production Under Chemical Elicitation Using Parallel Stable Isotope Labeling.

Rapid Synthesis and Diversification of Thymine-Containing Bridged Nucleic Acids Through Cascade Cyclization Reactions.

An Expedient Synthesis of the Antimitotic Natural Products Sarcodictyin and Eleutherobin, and Carbohydrate Analogues.

A gram-scale synthesis of &#x3b2;-L-carbafucose for engineering antibody glycans.

A sequential esterification-ring closing metathesis-Nozaki-Hiyama-Kishi strategy for constructing a natural product-like library of tetrahydrofuran-containing macrolides.

Unmasking the halide effect in diastereoselective Grignard reactions applied to C4&#xb4; modified nucleoside synthesis.

A flexible and scalable synthesis of 4'-thionucleosides.

Synthesis of the Phormidolide A Macrocycle Supports the Proposed Configurational Reassignment.

Hands-on high resolution mass spectrometer to support medicinal and materials chemistry

The Discovery and Development of Photactivatable Leaving Groups for Complex Molecule Synthesis

Global Center: International Research Center for Enhancing Plant Resilience

Global Center: International Research Center for Enhancing Plant Resilience

Rapid Synthesis of Nucleoside Analogues for Drug Discovery

Benchtop Walk-Up Time-of-Flight Mass Spectrometer

SARS-CoV-2 Rapid Research: Fast track isothermal viral diagnostics

Single turnover covalent chaperones for disease related lysosomal enzymes

A Scalable Synthesis of the C14-C23 Fragment of Eribulin_x000d_ _x000d_

Critical Acquisition of Modern, Functional Single-crystal X-ray Diffractometer Detector

Frequent collaborators

Gerhard Gries

Paul Schaffer

Travis Dudding

Ralph Pantophlet

A gram-scale synthesis of β-L-carbafucose for engineering antibody glycans.

Unmasking the halide effect in diastereoselective Grignard reactions applied to C4´ modified nucleoside synthesis.