This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Simon Fraser University directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Characterization of novel small molecule inhibitors of estrogen receptor-activation function 2 (ER-AF2).
Breast cancer research : BCR · 2024
Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator.
iScience · 2021
Latest funding
- $150,000
Hands-on high resolution mass spectrometer to support medicinal and materials chemistry
NSERC · 2025 · Principal investigator
- $75,000
Selective tissue-targeting controlled release prodrug technologies
NSERC · 2024 · Principal investigator
- $994,500
Targeting adaptive autophagy to enhance treatment response in pancreatic cancer
CIHR · 2024 · Co-investigator
2 publications.
Characterization of novel small molecule inhibitors of estrogen receptor-activation function 2 (ER-AF2).
Foo J, Gentile F, Massah S, Morin H, Singh K, Lee J, Smith J, Ban F, LeBlanc E, Young R, Strynadka N, Lallous N, Cherkasov A
Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator.
Laselva O, Qureshi Z, Zeng ZW, Petrotchenko EV, Ramjeesingh M, Hamilton CM, Huan LJ, Borchers CH, Pomès R, Young R, Bear CE
Hands-on high resolution mass spectrometer to support medicinal and materials chemistry
Principal investigators: Young, Robert
Keywords: medicinal chemistry; bioinorganic chemistry; chemical biology; materials sciences; drug discovery; drug development; pharmacokinetics; drug metabolism; drug target identification; enzymology
Selective tissue-targeting controlled release prodrug technologies
Principal investigators: Young, Robert
Keywords: prodrug; tissue targeting; controlled release; lung disease; colitis; asthma; cystic fibrosis; chronic obstructive pulmonary disease ; inflammatory bowel disease; aerosol
Targeting adaptive autophagy to enhance treatment response in pancreatic cancer
Principal investigators: Gorski, Sharon M
Keywords: Atg4; Autophagy; Biomarker; Cell Lines; Hydroxychloroquine; Mouse Model; Organoids; Pancreatic Cancer; Proof-Of-Principle; Treatment Resistance
Targeting adaptive autophagy to enhance treatment response in pancreatic cancer
Principal investigators: Gorski, Sharon M
Keywords: Atg4; Autophagy; Biomarker; Cell Lines; Hydroxychloroquine; Mouse Model; Organoids; Pancreatic Cancer; Proof-Of-Principle; Treatment Resistance
Investigating the relationship between HER2 and ATG4B in breast cancer.
Principal investigators: Gorski, Sharon M
Keywords: Atg4b; Autophagy; Breast Cancer; Cysteine Protease; Her2+; Mass Spectrometry; Mouse Model; Signal Transduction Pathways; Tissue Microarray; Xenograft
Topology and mechanism in self-immolation chemistry
Principal investigators: Young, Robert
Development of a novel conjugate drug for local delivery in bone grafts: Efficacy study on vascularization and osteogenesis after local delivery in a dental implant jaw model
Principal investigators: Young, Robert N
Keywords: Bisphosphonate; Dental Implants; Ep4 Receptor; Prodrug; Slow Release
Vancouver Autophagy Symposium 2014: Creation of a Pan-Canadian Network for Advancing Autophagy Research and Drug Development
Principal investigators: Gorski, Sharon M; Lum, Julian J; Young, Robert N
Keywords: Autophagy; Cancer; Commercialization; Inflammation; Networks; Small Molecule Inhibitors; Symposium; Therapeutic Target
NSERC CREATE Collaborative Medicinal Chemistry Network in Epigenetics Training (ChemNET):Training Canadian chemists within a global open access public-private partnership
Principal investigators: Edwards, Aled
Optimization of novel dual action prodrugs for treatment of osteoporosis
Principal investigators: Young, Robert
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Urologic Sciences
- Chemistry
Co-authors at Simon Fraser University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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