This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Regulatory T Cell Biomarkers Identify Patients at Risk of Developing Acute Cellular Rejection in the First Year Following Heart Transplantation.
Transplantation · 2023
HEARTBiT: A Transcriptomic Signature for Excluding Acute Cellular Rejection in Adult Heart Allograft Patients.
The Canadian journal of cardiology · 2020
SHIP2 phosphatase domain structure suggests sites of regulation (retrospective on DOI 10.1002/bies.201100195).
BioEssays : news and reviews in molecular, cellular and developmental biology · 2014 · senior author
Latest funding
- $50,000
COVID-19 Variant Supplement - The role of interleukin-10 responsiveness in lung inflammation in SARS CoV2 infection
CIHR · 2021 · Nominated PI
- $150,072
The role of interleukin-10 responsiveness in lung inflammation in SARS CoV2 infection
CIHR · 2020 · Nominated PI
- $100,000
Mechanism underlying hyporesponsiveness to Interleukin-10 in Type II Diabetes
CIHR · 2016 · Nominated PI
20 publications.
Regulatory T Cell Biomarkers Identify Patients at Risk of Developing Acute Cellular Rejection in the First Year Following Heart Transplantation.
Kim JV, Assadian S, Hollander Z, Burns P, Shannon CP, Lam K, Toma M, Ignaszewski A, Davies RA, Delgado D, Haddad H, Isaac D, Kim D, Mui A, Rajda M, West L, White M, Zieroth S, Keown PA, McMaster WR, Ng RT, McManus BM, Levings MK, Tebbutt SJ
HEARTBiT: A Transcriptomic Signature for Excluding Acute Cellular Rejection in Adult Heart Allograft Patients.
Shannon CP, Hollander Z, Dai DLY, Chen V, Assadian S, Lam KK, McManus JE, Zarzycki M, Kim Y, Kim JV, Balshaw R, Gidlöf O, Öhman J, Smith JG, Toma M, Ignaszewski A, Davies RA, Delgado D, Haddad H, Isaac D, Kim D, Mui A, Rajda M, West L, White M, Zieroth S, Tebbutt SJ, Keown PA, McMaster WR, Ng RT, McManus BM
SHIP2 phosphatase domain structure suggests sites of regulation (retrospective on DOI 10.1002/bies.201100195).
Wang F, Cheung S, Mui A
Hair follicle mesenchyme-associated PD-L1 regulates T-cell activation induced apoptosis: a potential mechanism of immune privilege.
Wang X, Marr AK, Breitkopf T, Leung G, Hao J, Wang E, Kwong N, Akhoundsadegh N, Chen L, Mui A, Carr N, Warnock GL, Shapiro J, McElwee KJ
Plasma protein biosignatures for detection of cardiac allograft vasculopathy.
Lin D, Cohen Freue G, Hollander Z, John Mancini GB, Sasaki M, Mui A, Wilson-McManus J, Ignaszewski A, Imai C, Meredith A, Balshaw R, Ng RT, Keown PA, Robert McMaster W, Carere R, Webb JG, McManus BM, Biomarkers in Transplantation Team, Networks of Centres of Excellence, Centres of Excellence for Commercialization and Research-Prevention of Organ Failure Centre of Excellence
Endogenous expression of B7-H4 improves long-term murine islet allograft survival.
Wang X, Hao J, Metzger DL, Mui A, Lee IF, Akhoundsadegh N, Ao Z, Chen L, Ou D, Verchere CB, Warnock GL
Blockade of both B7-H4 and CTLA-4 co-signaling pathways enhances mouse islet allograft survival.
Wang X, Hao J, Metzger DL, Mui A, Lee IF, Akhoundsadegh N, Chen CL, Ou D, Ao Z, Verchere CB, Warnock GL
B7-H4 Treatment of T Cells Inhibits ERK, JNK, p38, and AKT Activation.
Wang X, Hao J, Metzger DL, Ao Z, Chen L, Ou D, Verchere CB, Mui A, Warnock GL
B7-H4 induces donor-specific tolerance in mouse islet allografts.
Wang X, Hao J, Metzger DL, Mui A, Ao Z, Verchere CB, Chen L, Ou D, Warnock GL
Early treatment of NOD mice with B7-H4 reduces the incidence of autoimmune diabetes.
Wang X, Hao J, Metzger DL, Mui A, Ao Z, Akhoundsadegh N, Langermann S, Liu L, Chen L, Ou D, Verchere CB, Warnock GL
COVID-19 Variant Supplement - The role of interleukin-10 responsiveness in lung inflammation in SARS CoV2 infection
Principal investigators: Mui, Alice L
Keywords: Inflammation; Interleukin-10; Macrophage; Sars Cov2; Ship1 Inositol Phosphatase
The role of interleukin-10 responsiveness in lung inflammation in SARS CoV2 infection
Principal investigators: Mui, Alice L
Keywords: Inflammation; Interleukin-10; Macrophage; Sars Cov2; Ship1 Inositol Phosphatase
Mechanism underlying hyporesponsiveness to Interleukin-10 in Type II Diabetes
Principal investigators: Mui, Alice L; Elliott, Thomas G
Keywords: Ampk; Biomarker; Inflammation; Macrophage; Ship1 Inositol Phosphatase; Type 2 Diabetes
Regulation of microRNA maturation
Principal investigators: Mui, Alice
Negative Regulation of Immune Cell Function
Principal investigators: Mui, Alice L
Keywords: Inositol Phosphatase; Interleukin-10; Macrophage; Phagocytosis
IL-10 regulation of miRNA-542b-3p in activated macrophages
Principal investigators: So, Eva Yee Wah
Keywords: Cytokine Interleukin-10; Inflammation; Luciferase Assay; Macrophages; Microarray; Microrna; Qpcr; Signal Transduction
Interaction of IL-10R, STAT3 and SHIP1 upon IL-10 stimulation in macrophage
Principal investigators: So, Eva Yee Wah
Keywords: Animal Model; Bioinformatics; Facs; Immunoprecipitation; Inflammation; Interleukin-10; Macrophage; Mass Spectrometry; Real Time Qpcr; Signal Transduction
Negative Regulation of Immune Cell Function
Principal investigators: Mui, Alice L
Keywords: Inositol Phosphatase; Interleukin-10; Macrophage; Phagocytosis
Small molecule SHIP agonists for inhibiting the phosphoinositide 3-kinase pathway
Principal investigators: Mui, Alice L
Keywords: Biomarkers Of Disease; Hemopoietic Cancer; Phosphoinositide 3-Kinase Pathway; Signal Transduction; Targetted Therapeutics
Regulation of microRNA expression by interleukin-10 in activated macrophages
Principal investigators: Cheung, Tsz Ying Sylvia
Keywords: Cytokines; Immunology; Immunoregulation; Inflammation; Macrophages; Micrornas; Protein Purification; Real-Time Pcr; Signal Transduction; Transplantation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Surgery
- Pediatrics
- Urologic Sciences
- Computer Science
- Other
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