Faculty profile
Christopher Ong
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Longitudinal single-cell analysis reveals RUNX1T1 as an early driver in treatment-induced neuroendocrine transdifferentiation.
bioRxiv : the preprint server for biology · 2025
Exploring B7-H4's Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities.
Molecular cancer research : MCR · 2025
G9a in Cancer: Mechanisms, Therapeutic Advancements, and Clinical Implications.
Cancers · 2024
Latest funding
- $1,912,500
Derisking the Development of VPC-25959 Derivatives as Novel MCT4 Inhibitors for Clinical Trials in Patients with Advanced Glycolytic Cancers
CIHR · 2026 · Co-investigator
- $841,500
Targeting Epigenetic Phenotypic Switching to Overcome Prostate Cancer Treatment Resistance
CIHR · 2025 · Nominated PI
- $1,166,625
PROX1 Drives Cell Lineage Reprogramming in Neuroendocrine Prostate Cancer
CIHR · 2025 · Co-investigator
7 publications.
Longitudinal single-cell analysis reveals RUNX1T1 as an early driver in treatment-induced neuroendocrine transdifferentiation.
Ni Y, Lin D, Shi M, Lin YY, Xue H, Dong X, Liu L, Sar F, Wu R, Morova T, Haegert A, Bell R, Pang X, Classen A, Wang Y, Chen J, Volik S, Bihan SL, Lack N, Ong C, Wang G, Zeng H, Collins C, Wang Y
Exploring B7-H4's Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities.
Kang N, Xue H, Wong NKY, Lin YY, Classen A, Wu R, Oo HZ, Dong X, Trinh A, Lin D, Daugaard M, Ong C, Collins C, Gleave M, Wang Y
G9a in Cancer: Mechanisms, Therapeutic Advancements, and Clinical Implications.
Ni Y, Shi M, Liu L, Lin D, Zeng H, Ong C, Wang Y
Influence of ADT on B7-H3 expression during CRPC progression from hormone-naïve prostate cancer.
Kang N, Xue H, Lin YY, Dong X, Classen A, Wu R, Jin Y, Lin D, Volik S, Ong C, Gleave M, Collins C, Wang Y
Oncolysis of prostate cancers induced by vesicular stomatitis virus in PTEN knockout mice.
Moussavi M, Fazli L, Tearle H, Guo Y, Cox M, Bell J, Ong C, Jia W, Rennie PS
Predictive value of lymph node and tumor matrix metalloproteinase expression in the analysis of metastatic periampullary tumors.
McKenna GJ, Meneghetti A, Chen YL, Mui AL, Ong C, Scudamore CH, McMaster WR, Owen DA, Chung SW
Synthesis of pelorol and analogues: activators of the inositol 5-phosphatase SHIP.
Yang L, Williams DE, Mui A, Ong C, Krystal G, van Soest R, Andersen RJ
Derisking the Development of VPC-25959 Derivatives as Novel MCT4 Inhibitors for Clinical Trials in Patients with Advanced Glycolytic Cancers
Principal investigators: Wang, Yuzhuo
Keywords: Acidic Tumour Microenvironment; Altered Cancer Metabolism; Anticancer Immunity; Cancer-Generated Lactic Acid; Clinically-Focused Studies; Mct4; Pharmcodynamic Markers; Pre-Ind Enabling Studies; Small Molecule Inhibitor
Targeting Epigenetic Phenotypic Switching to Overcome Prostate Cancer Treatment Resistance
Principal investigators: Ong, Christopher J
Keywords: Computational Drug Design; Epigenetic Phenotypic Switching; Epigenetic Regulator; Nepc Transdifferentiation
PROX1 Drives Cell Lineage Reprogramming in Neuroendocrine Prostate Cancer
Principal investigators: Wang, Yuzhuo
Keywords: Nepc; Neuroendocrine Transdifferentiation; Prostate Cancer; Prox1; Transcription Factor
CHD7 as a key upstream chromatin regulator driving NEPC development and aggressiveness
Principal investigators: Wang, Yuzhuo
Keywords: Chd7; Neuroendocrine Transdifferentiation; Prostate Cancer
A master transcription factor driving cell lineage reprogramming in neuroendocrine prostate cancer development and progression
Principal investigators: Wang, Yuzhuo
Keywords: Nepc; Neuroendocrine Transdifferentiation; Prostate Cancer; Prox1; Transcription Factor
The Terry Fox New Frontiers Program on Prostate Cancer Progression (M. Gleave)
Principal investigators: Gleave, Martin E; Chi, Kim N; Collins, Colin C; Cox, Michael E; Guns, Emma S; Ong, Christopher J; Rennie, Paul S; Wang, Yuzhuo
Keywords: Genomic Markers; Prostate Cancer; Targeted Therapies; Translational Research
Small molecule SHIP agonists for inhibiting the phosphoinositide 3-kinase pathway
Principal investigators: Mui, Alice L
Keywords: Biomarkers Of Disease; Hemopoietic Cancer; Phosphoinositide 3-Kinase Pathway; Signal Transduction; Targetted Therapeutics
Borrelidin: a novel therapeutic agent for treatment of inflammatory diseases.
Principal investigators: Ogloff, Nadya A
Keywords: Animal Models; Cell Culture; Cytokines; Drug Development; Inflammatory Disease; Molecular Biology; Pharmacokinetics; Real Time Pcr; Signal Transduction
ERG-induced transformation of prostatic epithelial cells
Principal investigators: Cox, Michael E
Keywords: Animal Models; Epithelial-To-Mesenchymal Transition; Ets Transcription Factors; Metastasis; Prostate Cancer; Transformation
Investigation into the impact of certain micronutrients on lipid raft structure and associated IGF-IR signaling during prostate cancer progression
Principal investigators: Guns, Emma S
Keywords: Cell Signaling; Lc - Mass Spectrometry; Lipid Rafts; Micronutrients; Prostate Cancer; Prostate Cancer Progression Models
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Urologic Sciences
- Surgery
- Pathology and Laboratory Medicine
- Experimental Therapeutics
- Medicine/Neurology
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Yuzhuo Wang
Urologic Sciences
4 shared papers, latest 2025
Colin Collins
Urologic Sciences
3 shared papers, latest 2025
Martin Gleave
Urologic Sciences
2 shared papers, latest 2025
Alice Mui
Surgery
1 shared papers, latest 2005
Michael Cox
Urologic Sciences
1 shared papers, latest 2010
Mads Daugaard
Urologic Sciences
1 shared papers, latest 2025
Nathan Lack
Faculty
1 shared papers, latest 2025
Gang Wang
Pathology and Laboratory Medicine
1 shared papers, latest 2025
William Jia
Experimental Therapeutics
1 shared papers, latest 2010
Yu Wang
Medicine/Neurology
1 shared papers, latest 2025
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