Andre Marziali, University of British Columbia

Research

Read how they describe their research on their University of British Columbia profile.

Latest papers

Cultivating DNA Sequencing Technology After the Human Genome Project.
Annual review of genomics and human genetics · 2020 · senior author
Rapid and highly-specific generation of targeted DNA sequencing libraries enabled by linking capture probes with universal primers.
PloS one · 2018 · senior author
Duplex Proximity Sequencing (Pro-Seq): A method to improve DNA sequencing accuracy without the cost of molecular barcoding redundancy.
PloS one · 2018 · senior author

All 19 publications

Latest funding

NSERC CREATE Graduate program in Genome Science and Technology
NSERC · 2009 · Co-investigator
$1,650,000
Validation of Tissue and Cytology Microarray Spotter (TCMS) for Simultaneous Multiple Biomarker Detection in Cells
CIHR · 2008 · Co-investigator
$150,000
Response of intracellular signalling networks to time-varying signals
NSERC · 2006 · Principal investigator
$177,900

All 8 grants and awards

19 publications.

01

Cultivating DNA Sequencing Technology After the Human Genome Project.

Schloss JA, Gibbs RA, Makhijani VB, Marziali A

Annual review of genomics and human genetics2020Senior author

DOI: 10.1146/annurev-genom-111919-082433 PMID: 32283947

02

Rapid and highly-specific generation of targeted DNA sequencing libraries enabled by linking capture probes with universal primers.

Pel J, Leung A, Choi WWY, Despotovic M, Ung WL, Shibahara G, Gelinas L, Marziali A

PloS one2018Senior author

DOI: 10.1371/journal.pone.0208283 PMID: 30517195

03

Duplex Proximity Sequencing (Pro-Seq): A method to improve DNA sequencing accuracy without the cost of molecular barcoding redundancy.

Pel J, Choi WWY, Leung A, Shibahara G, Gelinas L, Despotovic M, Ung WL, Marziali A

PloS one2018Senior author

DOI: 10.1371/journal.pone.0204265 PMID: 30278055

04

Nanopore Analysis of Wild-Type and Mutant Prion Protein (PrPC): Single Molecule Discrimination and PrPC Kinetics

Nahid N. Jetha, Valentyna Semenchenko, David Scott Wishart, Neil R. Cashman, Andre Marziali

PLoS ONE201318 citationsSenior authorOpen Access

DOI: 10.1371/journal.pone.0054982 PMID: 23393562

05

Winnowing DNA for rare sequences: highly specific sequence and methylation based enrichment.

Thompson JD, Shibahara G, Rajan S, Pel J, Marziali A

PloS one2012Senior author

DOI: 10.1371/journal.pone.0031597 PMID: 22355378

06

Long Dwell-Time Passage of DNA through Nanometer-Scale Pores: Kinetics and Sequence Dependence of Motion

Nahid N. Jetha, Christopher Feehan, Matthew Wiggin, Vincent Tabard‐Cossa, Andre Marziali

Biophysical Journal201114 citationsSenior authorOpen Access

DOI: 10.1016/j.bpj.2011.05.007 PMID: 21689531

07

Efficient genomic DNA extraction from low target concentration bacterial cultures using SCODA DNA extraction technology.

So A, Pel J, Rajan S, Marziali A

Cold Spring Harbor protocols2010Senior author

DOI: 10.1101/pdb.prot5506 PMID: 20889703

08

Single-Molecule Bonds Characterized by Solid-State Nanopore Force Spectroscopy

Vincent Tabard‐Cossa, Matthew Wiggin, Dhruti Trivedi, Nahid N. Jetha, Jason R. Dwyer, Andre Marziali

ACS Nano200982 citationsSenior authorOpen Access

DOI: 10.1021/nn900713a PMID: 19751064

09

Nonlinear electrophoretic response yields a unique parameter for separation of biomolecules

Joel Pel, David Broemeling, Laura Mai, Hau-Ling Poon, G. Tropini, Robin M. Warren, Robert A. Holt, Andre Marziali

Proceedings of the National Academy of Sciences200960 citationsSenior authorOpen Access

DOI: 10.1073/pnas.0907402106 PMID: 19706437

10

Forming an alpha-hemolysin nanopore for single-molecule analysis.

Jetha NN, Wiggin M, Marziali A

Methods in molecular biology (Clifton, N.J.)2009Senior author

DOI: 10.1007/978-1-59745-483-4_9 PMID: 19488697

NSERC CREATE Graduate program in Genome Science and Technology

Co-investigatorNSERC2009Collaborative Research and Training Experience

Principal investigators: Withers, Stephen

$1,650,000

Validation of Tissue and Cytology Microarray Spotter (TCMS) for Simultaneous Multiple Biomarker Detection in Cells

Co-investigatorCIHR2008Proof of Principle Program - Phase I

Principal investigators: Banerjee, Diponkar

Keywords: Biomarker; Breast Cancer; Cytology; Fluorescence In-Situ Hybridization; Immunohistochemistry; Microarray

$150,000