Faculty profile
Marco Marra
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Research
Latest papers
Aneuploidy sensitizes cells to SREBP-pathway inhibition in squamous cell carcinoma.
bioRxiv : the preprint server for biology · 2026
Cross-Platform Methylation-Based Site of Origin Classification for Squamous Cell Carcinomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2025
The tandem duplicator phenotype may be a novel targetable subgroup in pancreatic cancer.
NPJ precision oncology · 2025
Latest funding
- $910,352
A single-cell spatial analysis of the impact of air pollution exposure on molecular pathways in lung cancer
CIHR · 2026 · Co-investigator
- $105,000
Discovery and characterization of extrachromosomal DNAs (ecDNAs) in human papillomavirus (HPV)-driven cancers
CIHR · 2022 · Supervisor
- $902,700
The impact of chromosomal instability on ovarian cancer progression
CIHR · 2022 · Co-investigator
54 publications.
Aneuploidy sensitizes cells to SREBP-pathway inhibition in squamous cell carcinoma.
Zhakula-Kostadinova N, Jain S, Amini-Farsani Z, Zhang J, Nakamura M, Byron L, Castellano Perez JJ, Paolucci C, Munoth R, Zandkarimi F, Takemon Y, Marra M, Henick B, Saqi A, Reya T, Meyerson M, Taylor AM
Cross-Platform Methylation-Based Site of Origin Classification for Squamous Cell Carcinomas.
Zhang AW, Akbari V, Galbraith A, Kore Z, Li Y, Leung S, Ji JX, Dever K, MacIsaac J, Brewis H, Pan D, Kürten C, Ajisebutu A, Contreras-Sanz A, Moeen A, Zuccato JA, Patil V, Black PC, Lam W, Pleasance E, O'Neill K, Jones S, Marra M, Laskin J, Zadeh G, Mansouri S, Kobor M, Prisman E, McGuire A, Huntsman DG, Yip S, Naso JR
The tandem duplicator phenotype may be a novel targetable subgroup in pancreatic cancer.
Farooq AR, Zhang AX, Chan-Seng-Yue M, Topham JT, O'Kane GM, Jang GH, Fischer S, Dodd A, Holter S, Wilson J, Grant RC, Aung KL, Zogopoulos G, Elimova E, Prince R, Jang R, Moore M, Biagi J, Tang P, Goodwin R, Bathe OF, Marra M, Laskin J, Renouf DJ, Schaeffer DF, Karasinska JM, Notta F, Gallinger S, Knox JJ, Tsang ES
Integrated single cell analysis reveals co-evolution of malignant B cells and tumor micro-environment in transformed follicular lymphoma.
Sarkozy C, Wu S, Takata K, Aoki T, Neriah SB, Milne K, Goodyear T, Strong C, Rastogi T, Hilton LK, Lai D, Sehn LH, Farinha P, Nelson BH, Weng A, Marra M, Scott DW, Craig JW, Steidl C, Roth A
Chronic Lymphocytic Leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing.
Grants JM, May C, Bridgers J, Huang S, Gillis S, Meissner B, Boyle M, Ben-Neriah S, Hung S, Duns G, Hilton L, Gerrie AS, Marra M, Kridel R, Sabatini PJB, Steidl C, Scott DW, Karsan A
Evaluating genomic biomarkers associated with resistance or sensitivity to chemotherapy in patients with advanced breast and colorectal cancer.
Guenter J, Abadi S, Lim H, Chia S, Woods R, Jones M, Rebic N, Renouf DJ, Laskin J, Marra M
Establishing a Framework for the Clinical Translation of Germline Findings in Precision Oncology.
Dixon K, Young S, Shen Y, Thibodeau ML, Fok A, Pleasance E, Zhao E, Jones M, Aubert G, Armstrong L, Virani A, Regier D, Gelmon K, Renouf D, Chia S, Bosdet I, Rassekh SR, Deyell RJ, Yip S, Fisic A, Titmuss E, Abadi S, Jones SJM, Sun S, Karsan A, Marra M, Laskin J, Lim H, Schrader KA
Patient selection for a developmental therapeutics program using whole genome and Transcriptome analysis.
Lavoie JM, Mitchell T, Lee SE, Deol B, Chia SK, Gelmon KA, Kollmannsberger CK, Tinker AV, Jones SJM, Marra M, Laskin J, Renouf DJ
Therapeutic Implication of Genomic Landscape of Adult Metastatic Sarcoma.
Feng X, Pleasance E, Zhao EY, Ng T, Grewal JK, Mohammad N, Taylor SK, Simmons C, Srikanthan A, Rassekh SR, Deyell R, Rauw J, Knowling M, Khoo K, Lee U, Noonan K, Hart J, Tonseth RP, Shen Y, Titmuss E, Jones M, Bonakdar M, Reisle C, Taylor GA, Chan S, Mungall K, Chuah E, Zhao Y, Mungall A, Moore R, Lim H, Renouf DJ, Gelmon K, Yip S, Jones SJM, Marra M, Laskin J
Application of a Neural Network Whole Transcriptome-Based Pan-Cancer Method for Diagnosis of Primary and Metastatic Cancers.
Grewal JK, Tessier-Cloutier B, Jones M, Gakkhar S, Ma Y, Moore R, Mungall AJ, Zhao Y, Taylor MD, Gelmon K, Lim H, Renouf D, Laskin J, Marra M, Yip S, Jones SJM
A single-cell spatial analysis of the impact of air pollution exposure on molecular pathways in lung cancer
Principal investigators: Lim, Emilia L
Keywords: Air Pollution; Anthracosis; Cellular Niches; Lung Cancer; Oncogenic Trajectories; Single Cell Rna-Seq; Spatial Transcriptomics; Transcriptomics
Discovery and characterization of extrachromosomal DNAs (ecDNAs) in human papillomavirus (HPV)-driven cancers
Principal investigators: MacLennan, Signe A
Keywords: Bioinformatics; Cancer Genomics; Cervical Cancer; Epigenetics; Extrachromosomal Dnas (Ecdnas); Genome Function; Genome Structure; Head And Neck Cancer; Human Papillomavirus (Hpv); Virally-Driven Cancers
The impact of chromosomal instability on ovarian cancer progression
Principal investigators: Steif, Adi
Keywords: Aneuploidy; Chromosomal Rearrangements; High Grade Serous Ovarian Cancer; Long-Read Sequencing; Probabilistic Models; Single Cell Sequencing; Whole Genome Doubling
Effect of HPV integration on 3D genome structure and function in cervical cancer
Principal investigators: Ng, Michelle
Keywords: 3d Genome Architecture; Cervical Cancer; Enhancer-Promoter Interactions; Epigenetics; Human Papillomavirus; Long Read Sequencing; Pore-C; Topologically Associating Domains; Viral Integration
Dissecting the determinants and dynamics of cellular states promoting glioma evolution
Principal investigators: Gaiti, Federico
Keywords: Cancer; Cellular States; Epigenetics; Evolution; Genotype; Glioma; Lineage Tracing; Plasticity; Single Cell; Tumor Micro-Environment
Discovery of HPV-associated genomic alterations in cervical cancer
Principal investigators: Marra, Marco A
Keywords: Cervical Cancer; Dna Methylation; Gene Fusions; Genomics; Human Papillomavirus (Hpv); Long-Read Dna Sequencing; Structural Variants; Transcriptome; Viral Integration
Long read DNA methylation sequencing for early detection of pancreatic adenocarcinoma
Principal investigators: Marra, Marco A; Jones, Steven
Keywords: Biomarker Discovery; Blood Samples; Development; Epigenomes; Epigenomics; Immunomodulation; Long Read Sequencing; Pancreatic
Dissecting tumour heterogeneity using single cell genomics, epigenomics and transcriptomics
Principal investigators: Marra, Marco A
Keywords: Tumour Heterogeneity
Deciphering the genome biology of relapsed lymphoid cancers to improve patient management
Principal investigators: Steidl, Christian
Keywords: Lymphoma
Heterogeneity through space and time drive the clinical behaviour of childhood medulloblastoma
Principal investigators: Taylor, Michael D
Keywords: Brain Tumors; Drug Screening; Genomics; Mouse Models; Pediatric Cancer; Xenografts
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Martin Hirst and Steven Jones: 15 shared papers
- Martin Hirst and Samuel Aparicio: 14 shared papers
- Samuel Aparicio and Andrew Roth: 14 shared papers
- Aly Karsan and Christian Steidl: 13 shared papers
- Marco Marra and Steven Jones: 13 shared papers
- Martin Hirst and Aly Karsan: 11 shared papers
- Martin Hirst and Inanc Birol: 11 shared papers
- Martin Hirst and Marco Marra: 11 shared papers
- Aly Karsan and Marco Marra: 8 shared papers
- Christian Steidl and Andrew Roth: 8 shared papers
- Calum Macaulay and Dirk Van Niekerk: 7 shared papers
- Martin Hirst and Christian Steidl: 5 shared papers
- Gelareh Zadeh and David Malkin: 5 shared papers
- Christian Steidl and Samuel Aparicio: 5 shared papers
- Samuel Aparicio and Steven Jones: 5 shared papers
- Martin Hirst and Andrew Roth: 4 shared papers
- Inanc Birol and Steven Jones: 4 shared papers
- Connie Eaves and Marco Marra: 3 shared papers
- Aly Karsan and Andrew Minchinton: 3 shared papers
- Aly Karsan and Inanc Birol: 3 shared papers
- Aly Karsan and Dean Regier: 3 shared papers
- Wan Lam and Marco Marra: 3 shared papers
- Connie Eaves and Martin Hirst: 2 shared papers
- Connie Eaves and Aly Karsan: 2 shared papers
- Andrew Weng and Christian Steidl: 2 shared papers
- Wan Lam and Christian Steidl: 2 shared papers
- Christian Steidl and Marco Marra: 2 shared papers
- Samuel Aparicio and Marco Marra: 2 shared papers
- Calum Macaulay and Marco Marra: 2 shared papers
- Inanc Birol and Marco Marra: 2 shared papers
- Marco Marra and Basile Tessier-Cloutier: 2 shared papers
- Faiyaz Notta and Elena Elimova: 2 shared papers
- Connie Eaves and James Thomson: 1 shared paper
- Martin Hirst and Wan Lam: 1 shared paper
- Martin Hirst and David Malkin: 1 shared paper
- Aly Karsan and David Malkin: 1 shared paper
- Aly Karsan and Basile Tessier-Cloutier: 1 shared paper
- Andrew Weng and Marco Marra: 1 shared paper
- Andrew Weng and Andrew Roth: 1 shared paper
- Wan Lam and Gelareh Zadeh: 1 shared paper
- Wan Lam and Calum Macaulay: 1 shared paper
- Wan Lam and Eitan Prisman: 1 shared paper
- Gelareh Zadeh and Marco Marra: 1 shared paper
- Gelareh Zadeh and Faiyaz Notta: 1 shared paper
- Gelareh Zadeh and Eitan Prisman: 1 shared paper
- Christian Steidl and Dean Regier: 1 shared paper
- James Thomson and Marco Marra: 1 shared paper
- Samuel Aparicio and Basile Tessier-Cloutier: 1 shared paper
- David Malkin and Marco Marra: 1 shared paper
- David Malkin and Faiyaz Notta: 1 shared paper
- Andrew Minchinton and Marco Marra: 1 shared paper
- Aslam Anis and Marco Marra: 1 shared paper
- Marco Marra and Dirk Van Niekerk: 1 shared paper
- Marco Marra and Laura Arbour: 1 shared paper
- Marco Marra and Dean Regier: 1 shared paper
- Marco Marra and Faiyaz Notta: 1 shared paper
- Marco Marra and Eitan Prisman: 1 shared paper
- Marco Marra and Elena Elimova: 1 shared paper
- Marco Marra and Krista Noonan: 1 shared paper
- Marco Marra and Andrew Roth: 1 shared paper
- Eitan Prisman and Elena Elimova: 1 shared paper
- Genome Sciences Centre
- Terry Fox Laboratory
- School of Population and Public Health
- Genetics
- Department of Microbiology and Immunology
- Obstetrics and Gynecology
- Pathology and Laboratory Medicine - The University of British Columbia
- Other
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Steven Jones
Genetics
13 shared papers, latest 2025
Martin Hirst
Department of Microbiology and Immunology
11 shared papers, latest 2015
Aly Karsan
Genome Sciences Centre
8 shared papers, latest 2024
Wan Lam
Faculty
3 shared papers, latest 2025
Connie Eaves
Terry Fox Laboratory
3 shared papers, latest 2011
Basile Tessier-Cloutier
Obstetrics and Gynecology
2 shared papers, latest 2019
Inanc Birol
Genome Sciences Centre
2 shared papers, latest 2017
Christian Steidl
Experimental Therapeutics
2 shared papers, latest 2024
Samuel Aparicio
Molecular Oncology
2 shared papers, latest 2008
Calum Macaulay
Pathology and Laboratory Medicine - The University of British Columbia
2 shared papers, latest 2007
Raymond Ng
Faculty
1 shared papers, latest 2006
Stephen Lam
Faculty
1 shared papers, latest 2006
Elena Elimova
Faculty
1 shared papers, latest 2025
Nevena Rebic
Faculty
1 shared papers, latest 2021
Michael Kobor
Department of Medical Genetics
1 shared papers, latest 2025
Eitan Prisman
Otolaryngology
1 shared papers, latest 2025
Krista Noonan
Department of Urologic Sciences
1 shared papers, latest 2019
Steven Gallinger
Department of Medical Biophysics
1 shared papers, latest 2025
Faiyaz Notta
Department of Medical Biophysics
1 shared papers, latest 2025
Laura Arbour
Department of Medical Genetics
1 shared papers, latest 2012
Vijay Ramaswamy
Developmental Stem Cell Biology
1 shared papers, latest 2018
Dean Regier
Cancer Control Research
1 shared papers, latest 2020
Martin Gleave
Department of Urologic Sciences
1 shared papers, latest 2012
Robert Kridel
Faculty
1 shared papers, latest 2024
Dirk Van Niekerk
School of Population and Public Health
1 shared papers, latest 2007
Andrew Roth
Faculty
1 shared papers, latest 2024
Peter Leung
Obstetrics and Gynecology
1 shared papers, latest 2009
Gelareh Zadeh
Neurosurgery
1 shared papers, latest 2025
Tobias Berg
Department of Oncology
1 shared papers, latest 2011
James Thomson
Journalism
1 shared papers, latest 2008
Nada Jabado
Pediatrics
1 shared papers, latest 2018
Aslam Anis
School of Population and Public Health
1 shared papers, latest 2012
David Malkin
Pediatrics
1 shared papers, latest 2018
Victor Ling
Faculty
1 shared papers, latest 2006
Andrew Minchinton
Faculty
1 shared papers, latest 2011
Andrew Weng
Terry Fox Laboratory
1 shared papers, latest 2024
Yuzhuo Wang
Department of Urologic Sciences
1 shared papers, latest 2012
Stirling Bryan
School of Population and Public Health
1 shared papers, latest 2012
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