Faculty profile
Calvin Yip
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Research
Latest papers
Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early-Onset Parkinsonism.
Annals of neurology · 2025
Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate.
Blood · 2010
Latest funding
- $120,000
Deciphering the molecular mechanism of the autophagy factor and Vici syndrome protein EPG5
CIHR · 2025 · Supervisor
- $1,051,875
Investigating the molecular mechanism of autophagosome-lysosome fusion
CIHR · 2024 · Nominated PI
- $105,000
Investigating the molecular mechanisms of PI4KA complex regulation
CIHR · 2023 · Supervisor
2 publications.
Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early-Onset Parkinsonism.
Dafsari HS, Deneubourg C, Singh K, Maroofian R, Suprenant Z, Kho AL, Ingham NJ, Steel KP, Sheshadri P, Baur F, Hentrich L, Gerisch B, Zamani M, Alves C, Siddiqui A, Dafsari HS, Salari M, Lang AE, Harris M, Abdelaleem A, Sadeghian S, Azizimalamiri R, Galehdari H, Shariati G, Sedaghat A, Zeighami J, Calame D, Marafi D, Duan R, Boehnke A, Clark GD, Rosenfeld JA, Mohila CA, Steel D, Chopra S, Sharma S, Kohlschmidt N, Patzer S, Saffari A, Ebrahimi-Fakhari D, Çavdartepe BE, Chang IJ, Beckman E, Peters R, Fennell AP, Lo B, Averdunk L, Distelmaier F, Baethmann M, Elmslie F, Joost K, Nampoothiri S, Yesodharan D, Mandel H, Kimball A, Kline AD, Mignot C, Keren B, Laugel V, Õunap K, Devadathan K, van Berkestijn FMC, Silwal A, Koene S, Verma S, Karim MY, Boubidi C, Aziz M, ElGhazali G, Mattas L, Miryounesi M, Hashemi-Gorji F, Alavi S, Nouri N, Noruzinia M, Kavousi S, Kamath A, Jayawant S, Saneto R, Haridy NA, Kart PO, Cansu A, Joubert M, Beneteau C, Stuurman KE, Wilke M, Barakat TS, Tajsharghi H, Scardamaglia A, Vallian S, Hız S, Shoeibi A, Boostani R, Hashemi N, Babaei M, Alsaleh NS, Porter J, Attié-Bitach T, Marzin P, Wicher D, Gold JI, Schuler E, Kashgari A, Alanazi RF, Eyaid W, Engelen M, Langeveld M, Stüve B, Li Y, Yigit G, Wollnik B, Monje MHG, Krainc D, Mencacci NE, Bakhtiari S, Kruer M, Argilli E, Sherr E, Jamshidi Y, Karimiani EG, Cheung YWS, Karin I, Zifarelli G, Bauer P, Chung WK, Lupski JR, Kurian MA, Dötsch J, von Kleist-Retzow JC, Klopstock T, Wagner M, Yip C, Roos A, Carsetti R, Dionisi-Vici C, Gautel M, Duchen MR, Antebi A, Houlden H, Fanto M, Jungbluth H
Properties of CD34+ CML stem/progenitor cells that correlate with different clinical responses to imatinib mesylate.
Jiang X, Forrest D, Nicolini F, Turhan A, Guilhot J, Yip C, Holyoake T, Jorgensen H, Lambie K, Saw KM, Pang E, Vukovic R, Lehn P, Ringrose A, Yu M, Brinkman RR, Smith C, Eaves A, Eaves C
Deciphering the molecular mechanism of the autophagy factor and Vici syndrome protein EPG5
Principal investigators: Shariati, Hannah R
Keywords: Autophagy; Endosomal Trafficking; Epg5; Membrane Fusion; Microscopy; Mitophagy; Primary Patient Fibroblast; Proximity-Labelling Mass Spectrometry; Rare Disease
Investigating the molecular mechanism of autophagosome-lysosome fusion
Principal investigators: Yip, Calvin K
Keywords: Autophagy; Confocal Microscopy; Cryo-Em; In Silico Structural Modelling; Mass Spectrometry; Membrane Fusion; Protein-Protein Interactions; Rab Gtpases; Structural Biology; Tethering Factors
Investigating the molecular mechanisms of PI4KA complex regulation
Principal investigators: Shaw, Alexandria L
Keywords: Cryo-Em; Hdx-Ms; Lipid Kinase; Lipid Signalling; Phosphoinositides; Pi4ka; Protein-Protein Interactions
Investigating the structure and function of the human autophagy regulator EPG5
Principal investigators: Yip, Calvin K
Keywords: Autophagy; Electron Microscopy; Epg5; Protein Purification; Protein-Protein Interaction; Structural Biology; X-Ray Crystallography
Microscope for Multicolour Single Molecule Fluorescence Detection, Imaging, and (Cross-)Correlation Spectroscopy
Principal investigators: Algar, WRuss
Structural and functional studies of histone acetyltransferase complexes
Principal investigators: Yip, Calvin
2019 Microscopical Society of Canada Annual Meeting
Principal investigators: Yip, Calvin K
Keywords: Biochemistry; Cancer; Cell Biology; Correlative Light-Electron Microscopy; Cryo Electron Microscopy; Infectious Diseases; Mechanisms Of Diseases; National Conference; Super Resolution Light Microscopy
Replacement of Life Sciences Institute Biomolecular Imager
Principal investigators: Jan, Eric
Operations and Maintenance Support: UBC Regional Structural Biology Facility
Principal investigators: McIntosh, Lawrence
Molecular mechanisms of autophagy regulation
Principal investigators: Yip, Calvin K
Keywords: Atg Proteins; Autophagosome; Macroautophagy; Membrane Remodeling; Protein Kinase; Selective Autophagy; Signal Transduction; Structural Biology; Transcriptional Regulation; Transmission Electron Microscopy
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Terry Fox Laboratory
- Biochemistry and Molecular Biology
- Electrical and Computer Engineering
Co-authors at University of British Columbia, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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