Faculty profile

Kirk Bergstrom

ResearcherBiologyUniversity of British Columbia

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses may be missing. Find their university profile.

Kirk Bergstrom

Researcher

Biology

Health Sciences

University of British Columbia

Vancouver, British Columbia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
9 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (2 CIHR, 2 NSERC), most recently in 2024.
Supervisor on 1 trainee award (1 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Colon Mucus Ex Vivo Glycosylation Gnotobiotics Goblet Cells In Vivo Innate Immunity Mucins

Latest papers

Bioengineering a Probiotic to Bloom During Colonic Inflammation Promotes Reliable Efficacy in Translational Models of Colitis.
Gastroenterology · 2026
Using MUC2 mucin producing tumorigenic human goblet-like cells to uncover functional properties of the mucus barrier.
Gut microbes · 2025
Defining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus.
Gut microbes · 2025

All 13 publications

Latest funding

Determining Dietary Influences on Gut Mucus Structure and Intestinal Inflammation.
CIHR · 2025 · Supervisor
$6,000
Mechanisms and therapeutic potential of microbial-driven mucus production by proximal colon goblet cells in colitis
CIHR · 2024 · Nominated PI
$25,000
Mechanisms and therapeutic potential of microbial-driven mucus production by proximal colon goblet cells in colitis
CIHR · 2024 · Nominated PI
$879,750

All 7 grants and awards

13 publications.

Bioengineering a Probiotic to Bloom During Colonic Inflammation Promotes Reliable Efficacy in Translational Models of Colitis.

Verdugo-Meza A, Gill SK, Godovannyi A, Chiang HM, Bosetti S, Barnett JA, Estaki M, Ishida R, Ye J, Quin C, Haskey N, Mehain H, Jafaripour S, Josephson JK, Ghesquiere C, Copp A, Usakiewicz J, Adur MK, Ghosh S, Bergstrom K, Sly LM, Gibson DL

Gastroenterology2026

DOI: 10.1053/j.gastro.2026.04.007 PMID: 42066862

Using MUC2 mucin producing tumorigenic human goblet-like cells to uncover functional properties of the mucus barrier.

Gorman H, Moreau F, Beaupré E, Nitin N, Zandberg WF, Bergstrom K, Gordon PMK, Dufour A, Chadee K

Gut microbes2025

DOI: 10.1080/19490976.2025.2542385 PMID: 40781862

Defining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus.

Chen Y, Gilliland A, Liang Q, Han X, Yang H, Chan J, Lévesque D, Moon KM, Daneshgar P, Boisvert FM, Foster L, Zandberg WF, Bergstrom K, Yu HB, Vallance BA

Gut microbes2025

DOI: 10.1080/19490976.2025.2494717 PMID: 40323239

Inflammasome activation links enteric Salmonella Typhimurium infection to a rapid, cytokine-dependent increase in intestinal mucin release.

Han X, Allaire JM, Crowley SM, Chan JJ, Lau K, Zhang C, Hirota SA, Bergstrom K, Knodler LA, Vallance BA

Gut microbes2024

DOI: 10.1080/19490976.2024.2413372 PMID: 39428744

The gut mucus network: A dynamic liaison between microbes and the immune system.

Inaba R, Vujakovic S, Bergstrom K

Seminars in immunology2023Senior author

DOI: 10.1016/j.smim.2023.101807 PMID: 37478802

Role of mucin glycosylation in the gut microbiota-brain axis of core 3 O-glycan deficient mice.

Coletto E, Savva GM, Latousakis D, Pontifex M, Crost EH, Vaux L, Telatin A, Bergstrom K, Vauzour D, Juge N

Scientific reports2023

DOI: 10.1038/s41598-023-40497-8 PMID: 37634035

Sweet-talk in the time of cholera: host mucin negotiates peace with Vibrio cholerae.

Bergstrom K

The EMBO journal2023First author

DOI: 10.15252/embj.2022113204 PMID: 36573348

Extraction and Verification of Mouse and Human Mucins from Tissue and Fecal Material.

Melvin M, Fancy N, Kniffen D, Bergstrom K

Methods in molecular biology (Clifton, N.J.)2023Senior author

DOI: 10.1007/978-1-0716-3151-5_14 PMID: 37149532

The barrier and beyond: Roles of intestinal mucus and mucin-type O-glycosylation in resistance and tolerance defense strategies guiding host-microbe symbiosis.

Bergstrom K, Xia L

Gut microbes2022First author

DOI: 10.1080/19490976.2022.2052699 PMID: 35380912

Reporting guidelines for human microbiome research: the STORMS checklist.

Mirzayi C, Renson A, Genomic Standards Consortium, Massive Analysis and Quality Control Society, Zohra F, Elsafoury S, Geistlinger L, Kasselman LJ, Eckenrode K, van de Wijgert J, Loughman A, Marques FZ, MacIntyre DA, Arumugam M, Azhar R, Beghini F, Bergstrom K, Bhatt A, Bisanz JE, Braun J, Bravo HC, Buck GA, Bushman F, Casero D, Clarke G, Collado MC, Cotter PD, Cryan JF, Demmer RT, Devkota S, Elinav E, Escobar JS, Fettweis J, Finn RD, Fodor AA, Forslund S, Franke A, Furlanello C, Gilbert J, Grice E, Haibe-Kains B, Handley S, Herd P, Holmes S, Jacobs JP, Karstens L, Knight R, Knights D, Koren O, Kwon DS, Langille M, Lindsay B, McGovern D, McHardy AC, McWeeney S, Mueller NT, Nezi L, Olm M, Palm N, Pasolli E, Raes J, Redinbo MR, Rühlemann M, Balfour Sartor R, Schloss PD, Schriml L, Segal E, Shardell M, Sharpton T, Smirnova E, Sokol H, Sonnenburg JL, Srinivasan S, Thingholm LB, Turnbaugh PJ, Upadhyay V, Walls RL, Wilmes P, Yamada T, Zeller G, Zhang M, Zhao N, Zhao L, Bao W, Culhane A, Devanarayan V, Dopazo J, Fan X, Fischer M, Jones W, Kusko R, Mason CE, Mercer TR, Sansone SA, Scherer A, Shi L, Thakkar S, Tong W, Wolfinger R, Hunter C, Segata N, Huttenhower C, Dowd JB, Jones HE, Waldron L

Nature medicine2021

DOI: 10.1038/s41591-021-01552-x PMID: 34789871

Determining Dietary Influences on Gut Mucus Structure and Intestinal Inflammation.

SupervisorCIHR2025Undergraduate Student Research Awards (USRA)

Principal investigators: Bigiremana, Benjamin

Keywords: Colon Cancer; Gut Mucus; Immunomodulatory Cytokine Expression; Infections; Inflammatory Bowel Disease; Sectioning Efficiency; Soft Diets

$6,000

Mechanisms and therapeutic potential of microbial-driven mucus production by proximal colon goblet cells in colitis

Nominated PICIHR2024PRIZE:Pro. GR. - PA: The Bhagirath Singh Early Career Prize in Inf. and Immunity

Principal investigators: Bergstrom, Kirk S

Keywords: Colon Mucus; Ex Vivo; Glycosylation; Gnotobiotics; Goblet Cells; In Vivo; Innate Immunity; Mucins; Organoid; Transgenic Reporter Mice

$25,000

Mechanisms and therapeutic potential of microbial-driven mucus production by proximal colon goblet cells in colitis

Nominated PICIHR2024Project Grant

Principal investigators: Bergstrom, Kirk S

Keywords: Colon Mucus; Ex Vivo; Glycosylation; Gnotobiotics; Goblet Cells; In Vivo; Innate Immunity; Mucins; Organoid; Transgenic Reporter Mice

$879,750

Restoring gut symbiosis caused by a Western diet through a Mediterranean-like diet combined with novel probiotics that target the gut-brain metabolic interactome

Co-investigatorCIHR2023Project Grant

Principal investigators: Gibson, Deanna L

Keywords: Colitis; Dysbiosis; Genetically Engineering Microbial Medicines; Gut Brain Axis; Gut Inflammation; Gut Microbiome; Immunometabolism; Inflammatory Bowel Diseases; Mediterranean Diet Pattern; Therapeutics

$765,000

Restoring gut symbiosis caused by a Western diet through a Mediterranean-like diet combined with novel probiotics that target the gut-brain metabolic interactome

Co-investigatorCIHR2022Project Grant - PA: Nutrition, Metabolism and Diabetes

Principal investigators: Gibson, Deanna L

Keywords: Colitis; Dysbiosis; Genetically Engineering Bacteria; Gut Brain Axis; Gut Inflammation; Gut Microbiome; Immunometabolism; Inflammatory Bowel Diseases; Therapeutics; Western Diet Pattern

$100,000

The Role of Mucin-type O-glycosylation in Fitness and Transmission of Intestinal Symbiotic Bacteria In Vivo

Principal investigatorNSERC2020Discovery Launch Supplement

Principal investigators: Bergstrom, Kirk

$12,500

The Role of Mucin-type O-glycosylation in Fitness and Transmission of Intestinal Symbiotic Bacteria In Vivo

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Bergstrom, Kirk

$185,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Kirk Bergstrom

Research

Latest papers

Latest funding

Bioengineering a Probiotic to Bloom During Colonic Inflammation Promotes Reliable Efficacy in Translational Models of Colitis.

Using MUC2 mucin producing tumorigenic human goblet-like cells to uncover functional properties of the mucus barrier.

Defining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus.

Inflammasome activation links enteric Salmonella Typhimurium infection to a rapid, cytokine-dependent increase in intestinal mucin release.

The gut mucus network: A dynamic liaison between microbes and the immune system.

Role of mucin glycosylation in the gut microbiota-brain axis of core 3 O-glycan deficient mice.

Sweet-talk in the time of cholera: host mucin negotiates peace with Vibrio cholerae.

Extraction and Verification of Mouse and Human Mucins from Tissue and Fecal Material.

The barrier and beyond: Roles of intestinal mucus and mucin-type O-glycosylation in resistance and tolerance defense strategies guiding host-microbe symbiosis.

Reporting guidelines for human microbiome research: the STORMS checklist.

Determining Dietary Influences on Gut Mucus Structure and Intestinal Inflammation.

Mechanisms and therapeutic potential of microbial-driven mucus production by proximal colon goblet cells in colitis

Mechanisms and therapeutic potential of microbial-driven mucus production by proximal colon goblet cells in colitis

Restoring gut symbiosis caused by a Western diet through a Mediterranean-like diet combined with novel probiotics that target the gut-brain metabolic interactome

Restoring gut symbiosis caused by a Western diet through a Mediterranean-like diet combined with novel probiotics that target the gut-brain metabolic interactome

The Role of Mucin-type O-glycosylation in Fitness and Transmission of Intestinal Symbiotic Bacteria In Vivo

The Role of Mucin-type O-glycosylation in Fitness and Transmission of Intestinal Symbiotic Bacteria In Vivo

Frequent collaborators

Bruce Vallance

Leonard Foster

Benjamin Haibe-Kains

Morgan Langille

Antoine Dufour

Sanjoy Ghosh

Wesley Zandberg