Faculty profile

Lakshmi Yatham

ResearcherPsychiatryUniversity of British Columbia

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of British Columbia directory, so their courses and email address may be missing. Find their university profile.

Lakshmi Yatham

Researcher

Psychiatry

Health Sciences

University of British Columbia

Vancouver, British Columbia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
7 publications in the last five years, latest in 2026.
Principal investigator on 7 research grants (7 CIHR), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Publications

Citations

Collaborators

Grants

Publications by year

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Signals and details

Research

Mental Health Depression Randomized Clinical Trial Administrative Data Artificial Intelligence Covid-19 Health Systems Machine Learning

Latest papers

Conceptual and pragmatic clinical implications of dichotomizing psychotropics as targeting physiology-physiomodal and pathology-pathomodal.
The international journal of neuropsychopharmacology · 2026
An international, double-blind, randomized, placebo-controlled clinical trial of adjunctive trimetazidine to treat people with bipolar depression (the TIDE trial) protocol.
BMC psychiatry · 2026
A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework.
Artificial intelligence in medicine · 2025

All 24 publications

Latest funding

Metformin for treatment-resistant bipolar depression (TRBD) with co-morbid insulin resistance (IR): A double-blind randomized control trial
CIHR · 2025 · Co-investigator
$1,510,875
A living systematic review, meta-analysis and dose-response of randomized controlled trials testing serotonergic psychedelics: efficacy, acceptability, tolerability, safety and publication bias within and across health conditions
CIHR · 2024 · Co-investigator
$348,076
Evaluating the efficacy of the PolarUs app on quality of life outcomes in people with bipolar disorder
CIHR · 2024 · Co-investigator
$757,350

All 17 grants and awards

24 publications.

Conceptual and pragmatic clinical implications of dichotomizing psychotropics as targeting physiology-physiomodal and pathology-pathomodal.

Berk M, Stahl SM, Yatham L, Narayanaswamy JC, Dodd S

The international journal of neuropsychopharmacology2026

DOI: 10.1093/ijnp/pyag006 PMID: 41697018

An international, double-blind, randomized, placebo-controlled clinical trial of adjunctive trimetazidine to treat people with bipolar depression (the TIDE trial) protocol.

Kim JH, Park CHJ, Reddy PV, Khanra S, Arumugham SS, Venkatasubramanian G, Debnath M, Arasappa R, Ashton MM, Panizzutti B, Turner A, Tholasappa V, Shukla D, Sadashiva ST, Raj J, Dombale S, Dean O, Mohebbi M, Vieta E, Pacchiarotti I, Umesh S, Walder K, Yatham L, Baek JH, Goyal N, Reddy YCJ, Kesavan M, Berk M

BMC psychiatry2026

DOI: 10.1186/s12888-026-08026-9 PMID: 41933313

A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework.

Sampaio IW, Tassi E, Bellani M, Benedetti F, Nenadić I, Phillips ML, Piras F, Yatham L, Bianchi AM, Brambilla P, Maggioni E

Artificial intelligence in medicine2025

DOI: 10.1016/j.artmed.2024.103063 PMID: 39837135

A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework.

Sampaio IW, Tassi E, Bellani M, Benedetti F, Nenadic I, Phillips M, Piras F, Yatham L, Bianchi AM, Brambilla P, Maggioni E

bioRxiv : the preprint server for biology2024

DOI: 10.1101/2024.09.04.611239 PMID: 39282436

Antipsychotic drugs in first-episode psychosis: a target trial emulation in the FEP-CAUSAL Collaboration.

Szmulewicz AG, Martínez-Alés G, Logan R, Ferrara M, Kelly C, Fredrikson D, Gago J, Conderino S, Díaz-Caneja CM, Galvañ J, Thorpe L, Srihari V, Yatham L, Sarpal DK, Shinn AK, Arango C, Öngür D, Hernán MA, Fep-Causal Collaboration OBOT

American journal of epidemiology2024

DOI: 10.1093/aje/kwae029 PMID: 38576166

Suicidal Ideation Amongst University Students During the COVID-19 Pandemic: Time Trends and Risk Factors.

Jones LB, Vereschagin M, Wang AY, Munthali RJ, Pei J, Richardson CG, Halli P, Xie H, Rush B, Yatham L, Gadermann AM, Pendakur K, Prescivalli AP, Munro L, Bruffaerts R, Auerbach RP, Mortier P, Vigo DV

Canadian journal of psychiatry. Revue canadienne de psychiatrie2023

DOI: 10.1177/07067437221140375 PMID: 36475311

A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression.

Jauhar S, Arnone D, Baldwin DS, Bloomfield M, Browning M, Cleare AJ, Corlett P, Deakin JFW, Erritzoe D, Fu C, Fusar-Poli P, Goodwin GM, Hayes J, Howard R, Howes OD, Juruena MF, Lam RW, Lawrie SM, McAllister-Williams H, Marwaha S, Matuskey D, McCutcheon RA, Nutt DJ, Pariante C, Pillinger T, Radhakrishnan R, Rucker J, Selvaraj S, Stokes P, Upthegrove R, Yalin N, Yatham L, Young AH, Zahn R, Cowen PJ

Molecular psychiatry2023

DOI: 10.1038/s41380-023-02095-y PMID: 37322065

Population Mental Health and COVID-19: Why Do We Know So Little?

Patten SB, Kutcher S, Streiner D, Gratzer D, Kurdyak P, Yatham L

Canadian Journal of Psychiatry20219 citationsSenior authorOpen Access

DOI: 10.1177/07067437211010523 PMID: W3155831627

Cariprazine in the Treatment of Bipolar Disorder: Within and Beyond Clinical Trials.

Do A, Keramatian K, Schaffer A, Yatham L

Frontiers in psychiatry2021Senior author

DOI: 10.3389/fpsyt.2021.769897 PMID: 34970166

[Association of COVID-19 dissemination with symptoms of anxiety and depression among university students].

Vigo D, Jones L, Munthali R, Pei J, Westenberg J, Munro L, Judkowicz C, Wang AY, Van den Adel B, Dulai J, Krausz M, Auerbach RP, Bruffaerts R, Yatham L, Gadermann A, Rush B, Xie H, Pendakur K, Richardson C

Vertex (Buenos Aires, Argentina)2021

DOI: 10.53680/vertex.v32i153.105 PMID: 34783787

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Lakshmi Yatham

Research

Latest papers

Latest funding

Conceptual and pragmatic clinical implications of dichotomizing psychotropics as targeting physiology-physiomodal and pathology-pathomodal.

An international, double-blind, randomized, placebo-controlled clinical trial of adjunctive trimetazidine to treat people with bipolar depression (the TIDE trial) protocol.

A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework.

A generalizable normative deep autoencoder for brain morphological anomaly detection: application to the multi-site StratiBip dataset on bipolar disorder in an external validation framework.

Antipsychotic drugs in first-episode psychosis: a target trial emulation in the FEP-CAUSAL Collaboration.

Suicidal Ideation Amongst University Students During the COVID-19 Pandemic: Time Trends and Risk Factors.

A leaky umbrella has little value: evidence clearly indicates the serotonin system is implicated in depression.

Population Mental Health and COVID-19: Why Do We Know So Little?

Cariprazine in the Treatment of Bipolar Disorder: Within and Beyond Clinical Trials.

[Association of COVID-19 dissemination with symptoms of anxiety and depression among university students].

Metformin for treatment-resistant bipolar depression (TRBD) with co-morbid insulin resistance (IR): A double-blind randomized control trial

A living systematic review, meta-analysis and dose-response of randomized controlled trials testing serotonergic psychedelics: efficacy, acceptability, tolerability, safety and publication bias within and across health conditions

Evaluating the efficacy of the PolarUs app on quality of life outcomes in people with bipolar disorder

Co-designing a living umbrella review platform informing guidelines and care for bipolar disorder

Psilocybin Assisted Therapy (PAT) for Treatment Resistant Depression in Bipolar II Disorder (TRD.BD-II): A Randomized Controlled Trial

Obesity, brain structure and cognitive functioning in major psychiatric disorders - large scale, multicenter study

Towards a Learning Health System to support an Integrated Youth Services Network in Canada

COVID-19 Variant Supplement - Predicting the risk of developing mental and substance use disorders due to COVID-19: machine learning applied to health service utilization data to facilitate access to effective treatments.

Cannabidiol Adjunctive Therapy for Acute Bipolar Depression: A Randomized Double-Blind Placebo Controlled Trial

Light and Ion Maintenance In Treatment of Depression (LIMIT-D) Trial: Feasibility Study

Frequent collaborators

Pierre Blier

Ayal Schaffer

Brian Rush

Gustavo Turecki

Anne Gadermann

Mark Sinyor

Daniel Vigo

Kamyar Keramatian

Arun Ravindran

Flavio Kapczinski

David Lloyd Streiner

Paul Kurdyak