Faculty profile
Pierre Blier
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Read how they describe their research on their University of Ottawa profile.
Latest papers
Differentiating suicide risk in treatment-resistant depression: clinical and functional imaging correlates of suicidal ideation and attempt.
NeuroImage. Clinical · 2026
Translating Pharmacokinetics and Pharmacodynamics into Clinical Decision-Making: A Practical Guide to the Use of Risperidone ISM® in Schizophrenia.
Journal of clinical medicine · 2026
Oral Clonidine and Brimonidine Eye Drops Attenuated Sertraline Discontinuation Symptoms.
Biological psychiatry · 2026 · first author
Latest funding
- $105,000
Metabolic correlates of antidepressant response to ketamine and electroconvulsive therapy: A pilot FDG-PET study
CIHR · 2021 · Supervisor
- $757,350
Mechanisms involved in triggering the rapid and sustained antidepressant effects of ketamine
CIHR · 2019 · Nominated PI
- $6,000
Functional and Structural Connectivityy Correlates Associated with Suicidal Behaviour.
CIHR · 2019 · Supervisor
From the 150 most recent of 159 publications.
Differentiating suicide risk in treatment-resistant depression: clinical and functional imaging correlates of suicidal ideation and attempt.
Burhunduli P, Fang Z, Vandeloo KL, Sharmin F, Blier P, Phillips JL
Translating Pharmacokinetics and Pharmacodynamics into Clinical Decision-Making: A Practical Guide to the Use of Risperidone ISM® in Schizophrenia.
Solmi M, Corbeil O, Miguelez M, Procyshyn RM, Blier P, Barakat M, Correll CU
Oral Clonidine and Brimonidine Eye Drops Attenuated Sertraline Discontinuation Symptoms.
Blier P, Almatrafi A, El Mansari M
Increase of the AMPA-evoked response of pyramidal neurons in the rat medial prefrontal cortex following acute administration of ketamine and S-ketamine, but not R-ketamine.
El Mansari M, Okamoto N, Blier P
Structural and functional neuroimaging correlates of suicidal ideation in treatment-resistant major depressive disorder.
Burhunduli P, Vandeloo KL, Fang Z, Blier P, Phillips JL
α5-GABAA allosteric modulation triggers and prolongs dopamine neuronal activity via AMPA receptors.
Ahmed A, El Mansari M, Blier P
Dose-dependent pharmacological mechanisms within the Neuroscience-based Nomenclature: a new concept to facilitate neuroscience-based prescribing.
Zemach S, Zohar J, Correll CU, Stahl SM, Drago F, Goodwin GM, Moller HJ, Uchida H, Siafis S, Santos M, Blier P
Deep learning using electroencephalogram (EEG) data for diagnosing and predicting SSRI response in major depressive disorder.
Olbrich S, Jaworska N, de la Salle S, Knott V, Blier P, Brunovsky M, Welt T, de Bardeci M, Teng-Ip C
Reinstatement of escitalopram and clonidine administration reverses the cessation-induced enhanced activation of rat norepinephrine and serotonin neuronal firing activity.
El Mansari M, Okamoto N, Blier P
Modulation of Brain Temporal Complexity During Treatment for Depression: A CAN-BIND-1 Study Report: Modulation de la complexité temporelle du cerveau pendant le traitement de la dépression: rapport de l’étude CAN-BIND-1
Stengel C, Schwartzmann B, Chatterjee R, Atluri S, Vaghei Y, Arnott SR, Blier P, Dhami P, Foster JA, Frey BN
Metabolic correlates of antidepressant response to ketamine and electroconvulsive therapy: A pilot FDG-PET study
Principal investigators: Burhunduli, Patricia
Keywords: Bipolar Disorder; Electroconvulsive Therapy; Intravenous Ketamine; Magnetic Resonance Imaging; Major Depressive Disorder; Positron Emission Tomorgraphy; Suicidal Ideation; Treatment Resistant Depression
Mechanisms involved in triggering the rapid and sustained antidepressant effects of ketamine
Principal investigators: Blier, Pierre
Keywords: Antidepressant; Clinical Pharmacology; Depression; Drug Metabolism; Glutamate; Glutamatergic System; Ketamine Mechanism Of Action; Major Depressive Disorder; Mechanism Of Drug Action; Nmda Anatognist
Functional and Structural Connectivityy Correlates Associated with Suicidal Behaviour.
Principal investigators: Vandeloo, Katie L
Keywords: Neuroimaging; Psychiatry; Structural Connectivity; Suicidal Behaviour; Treatment Resistant Depression
The Ottawa Neuroscience and Mental Health Trainee Network Conference
Principal investigators: Hamati, Rami
Keywords: Knowledge Translation; Mental Health; Neurology; Neurosciences; People With Lived Experiences; Personalized Interventions; Psychiatry; Psychology; Trainees; Translational Research
Optimization of the antidepressant action of ketamine in treatment-resistant depression and investigations on it's mechanism of action
Principal investigators: Blier, Pierre
Keywords: Antidepressant; Clinical Trials; Depression; Glutamate; Glutamatergic System; Ketamine; Major Depression; Mood Disorders; Nmda Antagonist; Treatment Resistant
Effect of small cerebral micro infarcts on the firing rates of monoaminergic systems in the rat brain
Principal investigators: Crnic, Agnes
Keywords: Depression; Dopamine; Electrophysiology; Late Onset Depression; Mental Health; Microinfarcts; Monoaminergic Systems; Neurophysiology; Neuropsychology; Neuroscience
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
Principal investigators: Blier, Pierre
Keywords: Crc Tier 1
Effects of Acute Combination Pharmacotherapy on Morning Smoking Abstinence Symptoms in Female Smokers
Principal investigators: Knott, Verner J
Keywords: Cognition; Eeg; Erp; Neuropharmacology; Nicotine Addiction
A comparison of the impact of genetic variation on hippocampal volume in treatment-resistant depression and chronic schizophrenia: a study in imaging genetics
Principal investigators: Phillips, Jennifer L
Keywords: Brain Atrophy; Depression; Genetic Polymorphisms; Hippocampus; Magnetic Resonance Imaging; Neuroanatomy; Neurodevelopment; Pharmacology; Schizophrenia; Treatment Resistance
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Psychiatry
- Psychiatry & Behavioural Neurosciences
- Cellular and Molecular Medicine
- Behavioural Neuroscience & Psychiatry
- Psychology
- Psychology, Neuroscience & Behaviour
- Other
Co-authors at University of Ottawa, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Gustavo Turecki
Psychiatry
23 shared papers, latest 2026
Benicio Frey
Psychiatry & Behavioural Neurosciences
23 shared papers, latest 2026
Verner Knott
Faculty
21 shared papers, latest 2026
Jane Foster
Psychiatry & Behavioural Neurosciences
21 shared papers, latest 2026
Rudolf Uher
Psychiatry
19 shared papers, latest 2026
Roumen Milev
Psychiatry
19 shared papers, latest 2026
Faranak Farzan
Faculty
14 shared papers, latest 2026
Natalia Jaworska
Cellular and Molecular Medicine
13 shared papers, latest 2026
Francesco Leri
Faculty
12 shared papers, latest 2025
Sara de la Salle
Faculty
10 shared papers, latest 2026
Valerie Taylor
Psychiatry & Behavioural Neurosciences
10 shared papers, latest 2025
Peter Giacobbe
Faculty
8 shared papers, latest 2024
Stefan Kloiber
Faculty
6 shared papers, latest 2025
Lakshmi Yatham
Psychiatry
4 shared papers, latest 2017
Venkat Bhat
Behavioural Neuroscience & Psychiatry
4 shared papers, latest 2024
Rami Hamati
Faculty
4 shared papers, latest 2021
Zahinoor Ismail
Psychiatry
3 shared papers, latest 2024
Olabisi Owoeye
Psychiatry
2 shared papers, latest 2022
Naguib Mechawar
Psychiatry
2 shared papers, latest 2023
Derek Fisher
Psychology
2 shared papers, latest 2016
Fidel Vila-Rodriguez
Psychiatry
2 shared papers, latest 2019
Alexander Mcgirr
Psychiatry
2 shared papers, latest 2024
Serge Beaulieu
Faculty
2 shared papers, latest 2024
Luciano Minuzzi
Psychiatry & Behavioural Neurosciences
2 shared papers, latest 2019
Michael Van Ameringen
Psychiatry & Behavioural Neurosciences
2 shared papers, latest 2024
Geoffrey Hall
Psychology, Neuroscience & Behaviour
2 shared papers, latest 2019
Taylor Hatchard
Psychiatry & Behavioural Neurosciences
1 shared papers, latest 2020
Zainab Samaan
Psychiatry & Behavioural Neurosciences
1 shared papers, latest 2024
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.