Research
Read how they describe their research on their University of Manitoba profile.
Latest papers
Multivariable analysis of myokines as biomarkers of frailty in females.
Experimental gerontology · 2026
Autophagy-exosome crosstalk in neurodegeneration: Mechanisms and therapeutic opportunities.
Pharmacology & therapeutics · 2026
Exercise-induced extracellular vesicles mediate apoptosis in human colon cancer cells in an exercise intensity-dependent manner.
European journal of applied physiology · 2025
Latest funding
- $93,000
Effect of exercise on skeletal muscle-derived extracellular vesicles and regulation of mitochondrial biogenesis
NSERC · 2022 · Principal investigator
- $12,500
Effect of exercise on skeletal muscle-derived extracellular vesicles and regulation of mitochondrial biogenesis
NSERC · 2022 · Principal investigator
14 publications.
Multivariable analysis of myokines as biomarkers of frailty in females.
Boreskie KF, Hay JL, Schwade D, Saleem A, Arora RC, Duhamel TA
Autophagy-exosome crosstalk in neurodegeneration: Mechanisms and therapeutic opportunities.
Sedighi S, Guan T, Michetti F, Cordani M, Barzegar Behrooz A, Sabouni F, Eshraghi M, Saleem A, Ghavami S, Aghanoori MR
Exercise-induced extracellular vesicles mediate apoptosis in human colon cancer cells in an exercise intensity-dependent manner.
Ozerklig B, Turkel I, Yilmaz M, Vaizoglu RD, Akan HS, Dikmen ZG, Saleem A, Kosar SN
The mitophagy receptor BNIP3L/Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.
Field JT, Chapman D, Hai Y, Ghavami S, West AR, Ozerklig B, Saleem A, Kline J, Mendelson AA, Kindrachuk J, Triggs-Raine B, Gordon JW
Extracellular Vesicles Released From Skeletal Muscle Post-Chronic Contractile Activity Increase Mitochondrial Biogenesis in Recipient Myoblasts.
Obi PO, Souza TFG, Özerkliğ B, Seif S, Bydak B, Klassen N, Duhamel TA, West AR, Gordon JW, Saleem A
Leishmania major Dihydrolipoyl dehydrogenase (DLD) is a key metabolic enzyme that drives parasite proliferation, pathology and host immune response.
Onwah SS, Mou Z, Gupta G, Obi P, Ikeogu N, Jia P, Zhang WW, Ghavami S, Saleem A, Uzonna J
Omega-3 polyunsaturated fatty acids modify glucose metabolism in THP-1 monocytes.
Byun M, Armon R, Souza T, Anderson H, Saleem A, Pauls SD
PI3K-dependent reprogramming of hexokinase isoforms controls glucose metabolism and functional responses of B lymphocytes.
Paradoski BT, Hou S, Mejia EM, Olayinka-Adefemi F, Fowke D, Hatch GM, Saleem A, Banerji V, Hay N, Zeng H, Marshall AJ
Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches.
Jahangiri B, Saei AK, Obi PO, Asghari N, Lorzadeh S, Hekmatirad S, Rahmati M, Velayatipour F, Asghari MH, Saleem A, Moosavi MA
Extracellular Vesicles as Predictors of Individual Response to Exercise Training in Youth Living with Obesity.
Pierdoná TM, Martin A, Obi PO, Seif S, Bydak B, Labouta HI, Eadie AL, Brunt KR, McGavock JM, Sénéchal M, Saleem A
Effect of exercise on skeletal muscle-derived extracellular vesicles and regulation of mitochondrial biogenesis
Principal investigators: Saleem, Ayesha
Keywords: chronic exercise; extracellular vesicles; exosomes; skeletal muscle; mitochondrial biogenesis; cell culture; proteomics; cre-lox recombination; transcriptomics
Effect of exercise on skeletal muscle-derived extracellular vesicles and regulation of mitochondrial biogenesis
Principal investigators: Saleem, Ayesha
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Kozeta Miliku and Christina Raimondi: 1 shared paper
- Kozeta Miliku and Ayesha Saleem: 1 shared paper
- Richard Keijzer and Ayesha Saleem: 1 shared paper
- Jude Uzonna and Ayesha Saleem: 1 shared paper
- Christina Raimondi and Ayesha Saleem: 1 shared paper
- Versha Banerji and Ayesha Saleem: 1 shared paper
- Jason Kindrachuk and Ayesha Saleem: 1 shared paper
- Jason Kindrachuk and Barbara Triggs-Raine: 1 shared paper
- Ayesha Saleem and Barbara Triggs-Raine: 1 shared paper
- Immunology
- Biochemistry and Medical Genetics
- Internal Medicine
- Medicine
- Department of Surgery
- Other
Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Barbara Triggs-Raine
Biochemistry and Medical Genetics
1 shared papers, latest 2025
Kozeta Miliku
Medicine
1 shared papers, latest 2021
Richard Keijzer
Department of Surgery
1 shared papers, latest 2021
Jude Uzonna
Immunology
1 shared papers, latest 2025
Christina Raimondi
Internal Medicine
1 shared papers, latest 2021
Versha Banerji
Immunology
1 shared papers, latest 2024
Jason Kindrachuk
Faculty
1 shared papers, latest 2025
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Profile data last refreshed on September 27, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.