Faculty profile
Barbara Triggs-Raine
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Manitoba directory, so their courses may be missing. Find their university profile.
Latest papers
A Novel Nonsense Variant in Ankyrin Repeat and Sterile Alpha Motif Domain-Containing 6 Promotes Polycystic Kidney Disease in Han:SPRD- Cy Rats and Its Homozygosity Is Prenatally Lethal.
Kidney360 · 2026
The mitophagy receptor BNIP3L/Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.
Autophagy · 2025
Genetic Deficiencies of Hyaluronan Degradation.
Cells · 2024 · senior author
Latest funding
- $547,740
Development of a therapeutic modality to treat GM2 gangliosidoses
CIHR · 2018 · Co-investigator
- $280,000
Characterization of HYAL2 and non-HYAL2 dependent pathways of hyaluronan degradation
NSERC · 2017 · Principal investigator
- $130,000
Pathways of glycosaminoglycan degradation.
NSERC · 2012 · Co-investigator
31 publications.
A Novel Nonsense Variant in Ankyrin Repeat and Sterile Alpha Motif Domain-Containing 6 Promotes Polycystic Kidney Disease in Han:SPRD- Cy Rats and Its Homozygosity Is Prenatally Lethal.
Pemberton TJ, Winter T, Hemming R, Blant A, Fresnoza AL, Barker EN, Ashiri M, Xiang B, Dolinsky VW, Triggs-Raine B, Aukema HM
The mitophagy receptor BNIP3L/Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.
Field JT, Chapman D, Hai Y, Ghavami S, West AR, Ozerklig B, Saleem A, Kline J, Mendelson AA, Kindrachuk J, Triggs-Raine B, Gordon JW
Genetic Deficiencies of Hyaluronan Degradation.
Fink SP, Triggs-Raine B
Characterization of HMGA2 variants expands the spectrum of Silver-Russell syndrome.
Maharaj AV, Cottrell E, Thanasupawat T, Joustra SD, Triggs-Raine B, Fujimoto M, Kant SG, van der Kaay D, Clement-de Boers A, Brooks AS, Aguirre GA, Martín Del Estal I, Castilla de Cortázar Larrea MI, Massoud A, van Duyvenvoorde HA, De Bruin C, Hwa V, Klonisch T, Hombach-Klonisch S, Storr HL
Elucidating the clinical spectrum and molecular basis of HYAL2 deficiency.
Fasham J, Lin S, Ghosh P, Radio FC, Farrow EG, Thiffault I, Kussman J, Zhou D, Hemming R, Zahka K, Chioza BA, Rawlins LE, Wenger OK, Gunning AC, Pizzi S, Onesimo R, Zampino G, Barker E, Osawa N, Rodriguez MC, Neuhann TM, Zackai EH, Keena B, Capasso J, Levin AV, Bhoj E, Li D, Hakonarson H, Wentzensen IM, Jackson A, Chandler KE, Coban-Akdemir ZH, Posey JE, Banka S, Lupski JR, Sheppard SE, Tartaglia M, Triggs-Raine B, Crosby AH, Baple EL
Increased phosphorylation of HexM improves lysosomal uptake and potential for managing GM2 gangliosidoses.
Benzie G, Bouma K, Battellino T, Cooper S, Hemming R, Kammouni W, Liu L, Do C, Khajehpour M, Perreault H, Kornfeld S, Triggs-Raine B, Mark BL
Generation of prolactin-inducible protein (Pip) knockout mice by CRISPR/Cas9-mediated gene engineering.
Terceiro LEL, Blanchard AAA, Edechi CA, Freznosa A, Triggs-Raine B, Leygue E, Myal Y
Bitter taste receptor T2R14 detects quorum sensing molecules from cariogenic Streptococcus mutans and mediates innate immune responses in gingival epithelial cells.
Medapati MR, Singh N, Bhagirath AY, Duan K, Triggs-Raine B, Batista EL, Chelikani P
Extracellular Superoxide Dismutase Regulates Early Vascular Hyaluronan Remodeling in Hypoxic Pulmonary Hypertension.
Tseng V, Ni K, Allawzi A, Prohaska C, Hernandez-Lagunas L, Elajaili H, Cali V, Midura R, Hascall V, Triggs-Raine B, Petrache I, Hart CM, Nozik-Grayck E
SPAM1/HYAL5 double deficiency in male mice leads to severe male subfertility caused by a cumulus-oocyte complex penetration defect.
Park S, Kim YH, Jeong PS, Park C, Lee JW, Kim JS, Wee G, Song BS, Park BJ, Kim SH, Sim BW, Kim SU, Triggs-Raine B, Baba T, Lee SR, Kim E
Development of a therapeutic modality to treat GM2 gangliosidoses
Principal investigators: Mark, Brian L
Keywords: Beta-Hexosaminidase; Blood Brain Barrier; Enzyme Replacement Therapy; Genome Editing; Gm2 Gangliosidosis; Lysosomal Storage Disease; Pharmacological Chaperones; Protein Engineering; Sandhoff Disease; Tay-Sachs Disease
Characterization of HYAL2 and non-HYAL2 dependent pathways of hyaluronan degradation
Principal investigators: Triggs-Raine, Barbara
Pathways of glycosaminoglycan degradation.
Principal investigators: Merz, David
Does ß-hexosaminidase play a significant role in hyaluronan degradation?
Principal investigators: Gushulak, Lara E
Keywords: Degradation Pathway Characterization; Exoglycosidases; Genotyping; Glycosaminoglycans; Histological Studies; Hyaluronan; Mouse Model Of Disease; Mucopolysaccharidosis
Canadian Genetic Diseases Network (CGDN) / Réseau Canadien de maladies génétiques
Principal investigators: Hayden, Michael
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Thomas Klonisch and Sabine Hombach-Klonisch: 50 shared papers
- Shyamala Dakshinamurti and Prashen Chelikani: 14 shared papers
- Prashen Chelikani and Kangmin Duan: 8 shared papers
- Sabine Hombach-Klonisch and Yvonne Myal: 3 shared papers
- Thomas Klonisch and Prashen Chelikani: 2 shared papers
- Thomas Klonisch and Yvonne Myal: 2 shared papers
- Sabine Hombach-Klonisch and Barbara Triggs-Raine: 2 shared papers
- Shyamala Dakshinamurti and Vernon Dolinsky: 1 shared paper
- Shyamala Dakshinamurti and Kangmin Duan: 1 shared paper
- Shyamala Dakshinamurti and Barbara Triggs-Raine: 1 shared paper
- Vernon Dolinsky and Brian Mark: 1 shared paper
- Vernon Dolinsky and Barbara Triggs-Raine: 1 shared paper
- Brian Mark and Barbara Triggs-Raine: 1 shared paper
- Thomas Klonisch and Barbara Triggs-Raine: 1 shared paper
- Thomas Klonisch and Mazdak Khajehpour: 1 shared paper
- Ruey-Chyi Su and Jason Kindrachuk: 1 shared paper
- Ruey-Chyi Su and Barbara Triggs-Raine: 1 shared paper
- Ruey-Chyi Su and Jiuyong Xie: 1 shared paper
- Prashen Chelikani and Yvonne Myal: 1 shared paper
- Prashen Chelikani and Barbara Triggs-Raine: 1 shared paper
- Yvonne Myal and Barbara Triggs-Raine: 1 shared paper
- Yvonne Myal and Jiuyong Xie: 1 shared paper
- Kangmin Duan and Barbara Triggs-Raine: 1 shared paper
- Jason Kindrachuk and Ayesha Saleem: 1 shared paper
- Jason Kindrachuk and Barbara Triggs-Raine: 1 shared paper
- Ayesha Saleem and Barbara Triggs-Raine: 1 shared paper
- Barbara Triggs-Raine and Hélène Perreault: 1 shared paper
- Barbara Triggs-Raine and Mazdak Khajehpour: 1 shared paper
- Barbara Triggs-Raine and Jiuyong Xie: 1 shared paper
- Hélène Perreault and Mazdak Khajehpour: 1 shared paper
- Human Anatomy and Cell Science
- Chemistry
- Biochemistry and Medical Genetics
- Microbiology
- Physiology and Pathophysiology
- Oral Biology
- Department of Oral Biology
- Other
Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Sabine Hombach-Klonisch
Human Anatomy and Cell Science
2 shared papers, latest 2024
Mazdak Khajehpour
Chemistry
1 shared papers, latest 2022
Hélène Perreault
Chemistry
1 shared papers, latest 2022
Jiuyong Xie
Physiology and Pathophysiology
1 shared papers, latest 2015
Vernon Dolinsky
Pharmacology and Therapeutics
1 shared papers, latest 2017
Brian Mark
Microbiology
1 shared papers, latest 2017
Thomas Klonisch
Human Anatomy and Cell Science
1 shared papers, latest 2024
Ruey-Chyi Su
Immunology
1 shared papers, latest 2015
Prashen Chelikani
Department of Oral Biology
1 shared papers, latest 2021
Yvonne Myal
Pathology
1 shared papers, latest 2022
Kangmin Duan
Oral Biology
1 shared papers, latest 2021
Jason Kindrachuk
Faculty
1 shared papers, latest 2025
Shyamala Dakshinamurti
Pediatrics
1 shared papers, latest 2008
Ayesha Saleem
Faculty
1 shared papers, latest 2025
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