Faculty profile
Julie Lajoie
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Latest papers
HIV-Exposed Seronegative Female Sex Workers Show Different Cellular Immune Profiles Across the Menstrual Cycle.
American journal of reproductive immunology (New York, N.Y. : 1989) · 2025 · senior author
The cervicovaginal microbiome associates with spatially restricted host transcriptional signatures throughout the human ectocervical epithelium and submucosa.
PLoS pathogens · 2025
Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution.
PLoS biology · 2025
Latest funding
- $100,000
Examining the "local biologies" of transgender people in Nairobi, Kenya: epidemiological, biological, and social determinants of STBBI vulnerability
CIHR · 2025 · Co-investigator
- $2,000,000
Inflammation, Sex hormones, and Human Papilloma Virus (HPV) Expression: Assessing their Relationship in Menopausal Women and Evaluating Interventions to Prevent Cervical Cancer in Older Women
CIHR · 2025 · Principal investigator
- $748,493
All Together 4 IDEAS: Inclusivity, Diversity, Equity, to Address drivers and interventions to curtail the Syndemics experienced by people diagnosed with HIV and Sexually Transmitted and Blood-Borne Infections
CIHR · 2024 · Co-investigator
36 publications.
HIV-Exposed Seronegative Female Sex Workers Show Different Cellular Immune Profiles Across the Menstrual Cycle.
Kowatsch MM, Omollo K, Bradley F, Månberg A, Nilsson P, Bergström S, Oyugi J, Kimani J, Broliden K, Fowke KR, Lajoie J
The cervicovaginal microbiome associates with spatially restricted host transcriptional signatures throughout the human ectocervical epithelium and submucosa.
Kaldhusdal V, Franzén Boger M, Burgener AD, Lajoie J, Omollo K, Kimani J, Tjernlund A, Fowke KR, Kwon DS, Edfeldt G, Broliden K
Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution.
Tessandier N, Elie B, Boué V, Selinger C, Rahmoun M, Bernat C, Grasset S, Groc S, Bedin AS, Beneteau T, Bonneau M, Graf C, Jacobs N, Kamiya T, Kerioui M, Lajoie J, Melki I, Prétet JL, Reyné B, Schlecht-Louf G, Sofonea MT, Supplisson O, Wymant C, Foulongne V, Guedj J, Hirtz C, Picot MC, Reynes J, Tribout V, Tuaillon É, Waterboer T, Segondy M, Bravo IG, Boulle N, Murall CL, Alizon S
Spatial transcriptomics unveils estrogen-modulated immune responses and structural alterations in the ectocervical mucosa of depot medroxyprogesterone acetate users.
Kaldhusdal V, Boger MF, Tjernlund A, Burgener AD, Bradley F, Lajoie J, Omollo K, Kimani J, Fowke K, Czarnewski P, Broliden K
Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women.
Franzén Boger M, Kaldhusdal V, Pascual-Reguant A, Kroh S, Uecker R, Burgener AD, Lajoie J, Omollo K, Kimani J, Fowke KR, Hauser AE, Tjernlund A, Broliden K
Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection.
Franzén Boger M, Hasselrot T, Kaldhusdal V, Miranda GHB, Czarnewski P, Edfeldt G, Bradley F, Rexaj G, Lajoie J, Omollo K, Kimani J, Fowke KR, Broliden K, Tjernlund A
Estradiol-mediated enhancement of the human ectocervical epithelial barrier correlates with desmoglein-1 expression in the follicular menstrual phase.
Bradley F, Stern A, Franzén Boger M, Mousavian Z, Dethlefsen O, Kaldhusdal V, Lajoie J, Omollo K, Bergström S, Månberg A, Nilsson P, Kimani J, Burgener AD, Tjernlund A, Sundling C, Fowke KR, Broliden K
Acetylsalicylic acid inhibition of the lipoxygenase pathway: Implications for HIV prevention.
Kowatsch MM, Winter T, Oyugi J, Kimani J, Lajoie J, Aukema HM, Fowke KR
Vaginal candida infection is associated with host molecular signatures of neutrophil activation in the adjacent ectocervical mucosa in Kenyan sex workers.
Hasselrot T, Boger MF, Kaldhusdal V, Åhlberg A, Omollo K, Lajoie J, Kimani J, Tjernlund A, Fowke KR, Czarnewski P, Broliden K
Hydroxychloroquine reduces T cells activation recall antigen responses.
Kowatsch MM, Lajoie J, Mwangi L, Omollo K, Oyugi J, Hollett N, Kimani J, Fowke KR
Examining the "local biologies" of transgender people in Nairobi, Kenya: epidemiological, biological, and social determinants of STBBI vulnerability
Principal investigators: Mckinnon, Lyle R; Kimani, Joshua; Lorway, Robert R
Keywords: Gender Identity; Sexually Transmitted Infections; Social Determinants Of Health; Sti Epidemiology; Sti Immunity; Transgender People'S Health
Inflammation, Sex hormones, and Human Papilloma Virus (HPV) Expression: Assessing their Relationship in Menopausal Women and Evaluating Interventions to Prevent Cervical Cancer in Older Women
Principal investigators: Fowke, Keith R; Kimani, Joshua; Lajoie, Julie
Keywords: Acetylsalicylic Acid; Aging; Anti-Inflammatory; Cervical Cancer; Hormones; Hpv; Immune Modulation; Immune Quiescence; Inflammation; Menopause
All Together 4 IDEAS: Inclusivity, Diversity, Equity, to Address drivers and interventions to curtail the Syndemics experienced by people diagnosed with HIV and Sexually Transmitted and Blood-Borne Infections
Principal investigators: Rueda, Zulma V; Cyr, Monica; Haworth-Brockman, Margaret J; Keynan, Yoav; Maier, Katharina H
Keywords: Community-Led Research; Gender; Health Inequalities; Hiv; Intersectionality; People Experiencing Houselessness; People Who Inject Drugs; Sex; Sexually Transmitted And Blood Borne Infections; Syndemics
All Together 4 IDEAS: Inclusivity, Diversity, Equity, to Address drivers and interventions to curtail the Syndemics experienced by people diagnosed with HIV and Sexually Transmitted and Blood-Borne Infections
Principal investigators: Rueda, Zulma V; Cyr, Monica; Haworth-Brockman, Margaret J; Keynan, Yoav; Maier, Katharina H
Keywords: Health Inequalities; Hiv; Intersectionality; People Experiencing Houselessness; People Who Inject Drugs; Sex And Gender; Sexually Transmitted And Blood Borne Infections; Syndemics
Targeting inflammation in older female sex workers enhances HPV clearance
Principal investigators: Lajoie, Julie; Odhiambo, Joyce A; Fowke, Keith R
Keywords: Acetylsalicylic Acid; Aging; Cervical Cancer; Hpv Persistence; Immune Response; Inflammation; Menopause; Perimenopause; Therapeutic
All Together 4 IDEAS: Inclusivity, Diversity, Equity, to Address drivers and interventions to curtail the Syndemics experienced by people diagnosed with HIV and Sexually Transmitted and Blood-Borne Infections
Principal investigators: Rueda, Zulma V; Cyr, Monica; Haworth-Brockman, Margaret J; Keynan, Yoav; Maier, Katharina H
Keywords: Community-Led Research; Gender; Health Inequalities; Hiv; Intersectionality; People Experiencing Houselessness; People Who Inject Drugs; Sex; Sexually Transmitted And Blood Borne Infections; Syndemics
The impact of Depot Medroxyacetate (DMPA) on inflammation in female sex workers-implication for HIV susceptibility
Principal investigators: Lajoie, Julie; Berard, Alicia R
Keywords: Dmpa; Female Genital Tract; Female Sex Workers; Hiv; Hormonal Contraception; Immune Activation; Immune Response; Inflammation; Sexually Transmitted Infection; Stress Hormones
Bringing together communities and basic science researchers to build stronger relationships
Principal investigators: Fowke, Keith R; Kimani, Joshua; Lajoie, Julie
Keywords: Community Based Research; Gender-Based Violence; High-Risk Community; Hiv; Hiv Prevention; Sex Worker
Identifying immune markers of HPV viral clearance
Principal investigators: Fowke, Keith R; Kimani, Joshua; Mckinnon, Lyle R
Keywords: B Cells; Cervical Cancer; Female Genital Tract; Hiv; Hpv; Immunity; Natural Killer Cells; T Cells; Therapeutic Vaccine
Inflammation and HPV persistence
Principal investigators: Fowke, Keith R; Kimani, Joshua
Keywords: Clearance; Hormones; Hpv; Immune Response; Inflammation; Natural Killer Cells; Persistence; T Cells; Therapeutic Vaccine
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medical Microbiology and Infectious Diseases
- Medicine
- Obstetrics and Gynecology
- Community Health Sciences
- Department of Laboratory Medicine and Pathobiology
Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Joshua Kimani
Medical Microbiology and Infectious Diseases
25 shared papers, latest 2025
Keith Fowke
Medical Microbiology and Infectious Diseases
3 shared papers, latest 2025
Charu Kaushic
Medicine
3 shared papers, latest 2021
Michael Surette
Medicine
2 shared papers, latest 2019
Yoav Keynan
Medical Microbiology and Infectious Diseases
1 shared papers, latest 2012
Alicia Berard
Medical Microbiology and Infectious Diseases
1 shared papers, latest 2023
Ken Kasper
Medical Microbiology and Infectious Diseases
1 shared papers, latest 2012
Tony Mazzulli
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2019
Rupert Kaul
Medicine
1 shared papers, latest 2014
Adam Burgener
Obstetrics and Gynecology
1 shared papers, latest 2018
Ali A Ashkar
Medicine
1 shared papers, latest 2019
Marissa Becker
Community Health Sciences
1 shared papers, latest 2012
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