Faculty profile

Keith Fowke

ResearcherDepartment of Medical Microbiology and Infectious DiseasesUniversity of Manitoba

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Manitoba directory, so their courses and email address may be missing. Find their university profile.

Keith Fowke

Researcher

Department of Medical Microbiology and Infectious Diseases

Max Rady College of Medicine

University of Manitoba

Winnipeg, Manitoba, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
2 publications in the last five years, latest in 2025.
Principal investigator on 23 research grants (23 CIHR), most recently in 2025.
Supervisor on 7 trainee awards (7 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Hiv Acetylsalicylic Acid Inflammation Cervical Cancer Hpv Immune Quiescence Knowledge Translation Hormones

Latest papers

Spatial transcriptomics unveils estrogen-modulated immune responses and structural alterations in the ectocervical mucosa of depot medroxyprogesterone acetate users.
Scientific reports · 2025
Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate.
PLoS pathogens · 2022
Proceedings of the Canadian Association for HIV Research: Canadian Foundation for Infectious Diseases Professional Development Workshop for Viral Researchers.
Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2019

All 8 publications

Latest funding

Enhancing surveillance and detection of Mpox across Africa
CIHR · 2025 · Co-investigator
$350,000
Inflammation, Sex hormones, and Human Papilloma Virus (HPV) Expression: Assessing their Relationship in Menopausal Women and Evaluating Interventions to Prevent Cervical Cancer in Older Women
CIHR · 2025 · Nominated PI
$2,000,000
Mentoring Future Leaders in HIV/STBBI Research
CIHR · 2025 · Co-investigator
$20,000

All 56 grants and awards

8 publications.

Spatial transcriptomics unveils estrogen-modulated immune responses and structural alterations in the ectocervical mucosa of depot medroxyprogesterone acetate users.

Kaldhusdal V, Boger MF, Tjernlund A, Burgener AD, Bradley F, Lajoie J, Omollo K, Kimani J, Fowke K, Czarnewski P, Broliden K

Scientific reports2025

DOI: 10.1038/s41598-024-83775-9 PMID: 39762272

Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate.

Bradley F, Franzén Boger M, Kaldhusdal V, Åhlberg A, Edfeldt G, Lajoie J, Bergström S, Omollo K, Damdimopoulos A, Czarnewski P, Månberg A, Oyugi J, Kimani J, Nilsson P, Fowke K, Tjernlund A, Broliden K

PLoS pathogens2022

DOI: 10.1371/journal.ppat.1010494 PMID: 35533147

Proceedings of the Canadian Association for HIV Research: Canadian Foundation for Infectious Diseases Professional Development Workshop for Viral Researchers.

Patel TR, Fowke K, Matejcic A, Evans DH, Grandvaux N, Halperin SA, MacDonald NE, van Marle G, Cooper C

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada2019

DOI: 10.3138/jammi.2018-0034 PMID: 36337747

Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses.

Ao Z, Wang L, Mendoza EJ, Cheng K, Zhu W, Cohen EA, Fowke K, Qiu X, Kobinger G, Yao X

PloS one2019

DOI: 10.1371/journal.pone.0216949 PMID: 31100082

Age and menopause affect the expression of specific cytokines/chemokines in plasma and cervical lavage samples from female sex workers in Nairobi, Kenya.

Sivro A, Lajoie J, Kimani J, Jaoko W, Plummer FA, Fowke K, Ball TB

Immunity & ageing : I & A2013

DOI: 10.1186/1742-4933-10-42 PMID: 24498919

A naturally occurring Vif mutant (I107T) attenuates anti-APOBEC3G activity and HIV-1 replication.

Peng J, Ao Z, Matthews C, Wang X, Ramdahin S, Chen X, Li J, Chen L, He J, Ball B, Fowke K, Plummer F, Embree J, Yao X

Journal of molecular biology2013

DOI: 10.1016/j.jmb.2013.05.015 PMID: 23707381

Characterization of anti-HIV activity mediated by R88-APOBEC3G mutant fusion proteins in CD4+ T cells, peripheral blood mononuclear cells, and macrophages.

Ao Z, Wang X, Bello A, Jayappa KD, Yu Z, Fowke K, He X, Chen X, Li J, Kobinger G, Yao X

Human gene therapy2011

DOI: 10.1089/hum.2010.012 PMID: 21182427

Characterization of a trypsin-dependent avian influenza H5N1-pseudotyped HIV vector system for high throughput screening of inhibitory molecules.

Ao Z, Patel A, Tran K, He X, Fowke K, Coombs K, Kobasa D, Kobinger G, Yao X

Antiviral research2008

DOI: 10.1016/j.antiviral.2008.02.001 PMID: 18359097

Enhancing surveillance and detection of Mpox across Africa

Co-investigatorCIHR2025Team Grant: Monkeypox Rapid Research Response - Extension

Principal investigators: Kindrachuk, Kenneth J; Ansumana, Rashid; Mbala, Placide K

Keywords: Clades; Clinical Outcomes; Correlates Of Protection; Endemic; Monkeypox; Mpox; Publice Health; Serology; Surveillance; Vaccine Effectiveness

$350,000

Inflammation, Sex hormones, and Human Papilloma Virus (HPV) Expression: Assessing their Relationship in Menopausal Women and Evaluating Interventions to Prevent Cervical Cancer in Older Women

Nominated PICIHR2025Team Grant: Bringing Biology to Cancer Prevention - Cancer in Women

Principal investigators: Fowke, Keith R; Kimani, Joshua; Lajoie, Julie

Keywords: Acetylsalicylic Acid; Aging; Anti-Inflammatory; Cervical Cancer; Hormones; Hpv; Immune Modulation; Immune Quiescence; Inflammation; Menopause

$2,000,000

Mentoring Future Leaders in HIV/STBBI Research

Co-investigatorCIHR2025Planning and Dissemination Grants - Institute/Initiative Community Support

Principal investigators: Matejcic, Andrew J

Keywords: Hiv/Aids; Knowledge Translation; Mentorship; Multidisciplinary; Networking; Training

$20,000

Strengthening global health research capacity among the Canadian HIV/STBBI research community

Co-investigatorCIHR2024Planning and Dissemination Grant - Institute Community Support

Principal investigators: McClarty, Leigh M; Becker, Marissa

Keywords: Canadian Researchers; Capacity Strengthening; Early Career Researchers; Global Health Research; Hiv; Knowledge Exchange And Mobilization; Sexually Transmitted And Blood-Borne Infections

$20,000

All Together 4 IDEAS: Inclusivity, Diversity, Equity, to Address drivers and interventions to curtail the Syndemics experienced by people diagnosed with HIV and Sexually Transmitted and Blood-Borne Infections

Co-investigatorCIHR2024Tm Gr.:Embracing Diversity to Achieve Precision/Health Equity-KM Hub Supplement

Principal investigators: Rueda, Zulma V; Cyr, Monica; Haworth-Brockman, Margaret J; Keynan, Yoav; Maier, Katharina H

Keywords: Community-Led Research; Gender; Health Inequalities; Hiv; Intersectionality; People Experiencing Houselessness; People Who Inject Drugs; Sex; Sexually Transmitted And Blood Borne Infections; Syndemics

$748,493

Sex and Gender Equity Across the HIV Research Landscape: An Ancillary Session

Principal investigatorCIHR2024Planning and Dissemination Grant - Institute Community Support

Principal investigators: Gingras, Shanelle N; Fowke, Keith R

Keywords: Equity In Research Populations; Equity In Science; Equity, Diversity, And Inclusion; Hiv; Knowledge Translation; Planning And Dissemination; Sex And Gender Equity; Sex And Gender-Based Analysis

$20,000

MB NEIHR renewal

Co-investigatorCIHR2024Operating Grant: NEIHR - Manitoba

Principal investigators: Diffey, Linda L; Copenace, Sherry; Daniels, Chantal G; Star, Leona; Fowler-Woods, Amanda D; Lavoie, Josée G

Keywords: Anti-Indigenous Racism; Equity; Health Research; Indigenous Peoples; Mentorship

$4,000,000

Generating national awareness and spurring action to the unique syndemics driving the extreme rates of HIV and STBBI in the Prairies

Co-investigatorCIHR2024Planning and Dissemination Grant - Institute Community Support

Principal investigators: Becker, Marissa

Keywords: Hiv; Prairies; Stbbi; Syndemics

$20,000

Targeting inflammation in older female sex workers enhances HPV clearance

Principal investigatorCIHR2024Ca. Gr.: Biomedical Res. for HIV/AIDS/STBBI -Next-gen. therapeutic interventions

Principal investigators: Lajoie, Julie; Odhiambo, Joyce A; Fowke, Keith R

Keywords: Acetylsalicylic Acid; Aging; Cervical Cancer; Hpv Persistence; Immune Response; Inflammation; Menopause; Perimenopause; Therapeutic

$200,000

Canadian HIV Cure Enterprise 3.0: Targeting tissue HIV reservoirs

Co-investigatorCIHR2024TG: Biomedical Res. for HIV/AIDS/STBBI-Next-Gen.Therapeutic Interv.-Large Team

Principal investigators: Chomont, Nicolas; Margolese, Shari L; Ancuta, Petronela; Angel, Jonathan B; Cohen, Eric A; Costiniuk, Cecilia T; Murooka, Thomas T

Keywords: Cd4 T Cells; Hiv Cure; Hiv Immunity; Hiv Persistence; Hiv Reservoir; Human Studies; Humanized Mouse Models; Myeloid Cells; Therapeutic Interventions; Tissue

$3,750,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Hiv Dear Professor Fowke, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Spatial transcriptomics unveils estrogen-modulated immune responses and structural alterations in the ectocervical mucosa of depot medroxyprogesterone acetate users." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Inflammation, Sex hormones, and Human Papilloma Virus (HPV) Expression: Assessing their Relationship in Menopausal Women and Evaluating Interventions to Prevent Cervical Cancer in Older Women" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

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Keith Fowke

Research

Latest papers

Latest funding

Spatial transcriptomics unveils estrogen-modulated immune responses and structural alterations in the ectocervical mucosa of depot medroxyprogesterone acetate users.

Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate.

Proceedings of the Canadian Association for HIV Research: Canadian Foundation for Infectious Diseases Professional Development Workshop for Viral Researchers.

Incorporation of Ebola glycoprotein into HIV particles facilitates dendritic cell and macrophage targeting and enhances HIV-specific immune responses.

Age and menopause affect the expression of specific cytokines/chemokines in plasma and cervical lavage samples from female sex workers in Nairobi, Kenya.

A naturally occurring Vif mutant (I107T) attenuates anti-APOBEC3G activity and HIV-1 replication.

Characterization of anti-HIV activity mediated by R88-APOBEC3G mutant fusion proteins in CD4+ T cells, peripheral blood mononuclear cells, and macrophages.

Characterization of a trypsin-dependent avian influenza H5N1-pseudotyped HIV vector system for high throughput screening of inhibitory molecules.

Enhancing surveillance and detection of Mpox across Africa

Inflammation, Sex hormones, and Human Papilloma Virus (HPV) Expression: Assessing their Relationship in Menopausal Women and Evaluating Interventions to Prevent Cervical Cancer in Older Women

Mentoring Future Leaders in HIV/STBBI Research

Strengthening global health research capacity among the Canadian HIV/STBBI research community

All Together 4 IDEAS: Inclusivity, Diversity, Equity, to Address drivers and interventions to curtail the Syndemics experienced by people diagnosed with HIV and Sexually Transmitted and Blood-Borne Infections

Sex and Gender Equity Across the HIV Research Landscape: An Ancillary Session

MB NEIHR renewal

Generating national awareness and spurring action to the unique syndemics driving the extreme rates of HIV and STBBI in the Prairies

Targeting inflammation in older female sex workers enhances HPV clearance

Canadian HIV Cure Enterprise 3.0: Targeting tissue HIV reservoirs

Frequent collaborators

Julie Lajoie

Joshua Kimani

Gary Kobinger

Guido van Marle

Kevin Coombs

Andrew Matejcic

Darwyn Kobasa

Curtis Cooper