Faculty profile
Jun-Feng Wang
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Manitoba directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Introducing Borsantrazole: A Trifunctional Boron-Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
Thioredoxin interacting protein mediates corticosterone-induced depressive-like behavior in male mice.
Hormones and behavior · 2026 · senior author
Redox Protein Thioredoxin Mediates Neurite Outgrowth in Primary Cultured Mouse Cerebral Cortical Neurons.
Neuroscience · 2024 · senior author
Latest funding
- $623,475
The role of neuronal and glial thioredoxin-interacting protein in chronic stress-induced neuronal dysfunction: indications for depression and cognitive impairment
CIHR · 2020 · Nominated PI
- $192,000
The role of thioredoxin system in regulation of synaptic development and neurotransmission in the central nervous system
NSERC · 2020 · Principal investigator
- $175,000
The role of reversible oxidative protein modification in regulation of neurotransmitter systems
NSERC · 2014 · Principal investigator
16 publications.
Introducing Borsantrazole: A Trifunctional Boron-Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice.
Sanghai N, Kelley R, Lao Y, Madlangsakay MIR, Paul P, Llanes-Cuesta MA, Wang JF, Zahedi RP, Kong J, Tranmer GK
Thioredoxin interacting protein mediates corticosterone-induced depressive-like behavior in male mice.
Llanes-Cuesta MA, Tan H, Khasraghi AA, Wang JF
Redox Protein Thioredoxin Mediates Neurite Outgrowth in Primary Cultured Mouse Cerebral Cortical Neurons.
Alejandra Llanes-Cuesta M, Hoi V, Ha R, Tan H, Imamul Islam M, Eftekharpour E, Wang JF
Regulatory role of cathepsin L in induction of nuclear laminopathy in Alzheimer's disease.
Islam MI, Nagakannan P, Shcholok T, Contu F, Mai S, Albensi BC, Del Bigio MR, Wang JF, Sharoar MG, Yan R, Park IS, Eftekharpour E
Upregulation of antioxidant thioredoxin by antidepressants fluoxetine and venlafaxine.
Bharti V, Tan H, Deol J, Wu Z, Wang JF
Txnip mediates glucocorticoid-activated NLRP3 inflammatory signaling in mouse microglia.
Bharti V, Tan H, Zhou H, Wang JF
Increased thioredoxin-interacting protein in brain of mice exposed to chronic stress.
Zhou H, Tan H, Letourneau L, Wang JF
Upregulation of Thioredoxin-Interacting Protein in Brain of Amyloid-β Protein Precursor/Presenilin 1 Transgenic Mice and Amyloid-β Treated Neuronal Cells.
Wang Y, Wang Y, Bharti V, Zhou H, Hoi V, Tan H, Wu Z, Nagakannan P, Eftekharpour E, Wang JF
Glucocorticoid Upregulates Thioredoxin-interacting Protein in Cultured Neuronal Cells.
Bharti V, Tan H, Chow D, Wang Y, Nagakannan P, Eftekharpour E, Wang JF
The role of neuroinflammation and amyloid in cognitive impairment in an APP/PS1 transgenic mouse model of Alzheimer's disease.
Zhu S, Wang J, Zhang Y, He J, Kong J, Wang JF, Li XM
The role of neuronal and glial thioredoxin-interacting protein in chronic stress-induced neuronal dysfunction: indications for depression and cognitive impairment
Principal investigators: Wang, Jun-Feng
Keywords: Behavioural Tests; Cell Culture; Chronic Stress; Corticosterone; Depression; Gene Knockout; Inflammation; Mouse Brain; Oxidative Stress; Thioredoxin
The role of thioredoxin system in regulation of synaptic development and neurotransmission in the central nervous system
Principal investigators: Wang, Jun-Feng
The role of reversible oxidative protein modification in regulation of neurotransmitter systems
Principal investigators: Wang, JunFeng
Oxidative damage and compromised neuronal integrity in bipolar disorder
Principal investigators: Young, Trevor
Keywords: Bipolar Disorder; Mitochondrial Dysfunction; Oxidative Stress; Postmortem Brain Studies
Neuroprotective Effect of Mood Stabilizers: the Role of the Major Brain Antioxidant Glutathione
Principal investigators: Wang, Jun-Feng
Keywords: Bipolar Disorder; Glutathione; Mitochondrial Dysfunction; Mood Stabilizer; Neuroprotection; Oxidative Damage
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Pharmacology and Therapeutics
- Human Anatomy & Cell Science
- Psychiatry
- Physiology
Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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