Oleg Krokhin, University of Manitoba

Research

LC-MS peptide chromatography peptide retention prediction proteomics separation science

Latest papers

Peptide retention time prediction for electrostatic repulsion-hydrophilic interaction chromatography.
Journal of chromatography. A · 2024 · senior author
Accelerating Proteomics Using Broad Specificity Proteases.
Journal of proteome research · 2024
Cytoplasmic Shotgun Proteomic Points to Key Proteins and Pathways in Temozolomide-Resistant Glioblastoma Multiforme.
Journal of proteome research · 2024

All 35 publications

Latest funding

Cigarette smoking as a modifiable risk factor for Rheumatoid Arthritis development in First Nations Peoples.
CIHR · 2026 · Co-investigator
$914,176
Cigarette smoking induced neutrophilic inflammation as a modifiable risk factor for Rheumatoid Arthritis in First Nations
CIHR · 2024 · Co-investigator
$100,000
Peptide chromatography: comprehensive coverage of separation mechanisms for advanced proteomic applications
NSERC · 2022 · Principal investigator
$72,000

All 9 grants and awards

35 publications.

01

Peptide retention time prediction for electrostatic repulsion-hydrophilic interaction chromatography.

Neale Q, Yeung D, Spicer V, Perreault H, Krokhin O

Journal of chromatography. A2024Senior author

DOI: 10.1016/j.chroma.2024.465414 PMID: 39378622

02

Accelerating Proteomics Using Broad Specificity Proteases.

Jiang X, Yeung D, Liu Y, Spicer V, Afshari H, Lao Y, Lin F, Krokhin O, Zahedi RP

Journal of proteome research2024

DOI: 10.1021/acs.jproteome.3c00852 PMID: 38457694

03

Cytoplasmic Shotgun Proteomic Points to Key Proteins and Pathways in Temozolomide-Resistant Glioblastoma Multiforme.

Teraiya M, Krokhin O, Chen VC, Perreault H

Journal of proteome research2024

DOI: 10.1021/acs.jproteome.3c00669 PMID: 38147655

04

Exploring the variable space of shallow machine learning models for reversed-phase retention time prediction.

Yeung D, Spicer V, Zahedi RP, Krokhin O

Computational and structural biotechnology journal2023Senior author

DOI: 10.1016/j.csbj.2023.02.047 PMID: 37090433

05

Acetic Acid Ion Pairing Additive for Reversed-Phase HPLC Improves Detection Sensitivity in Bottom-up Proteomics Compared to Formic Acid.

Battellino T, Ogata K, Spicer V, Ishihama Y, Krokhin O

Journal of proteome research2023Senior author

DOI: 10.1021/acs.jproteome.2c00388 PMID: 36480176

06

Rodent Lung Tissue Sample Preparation and Processing for Shotgun Proteomics.

Piyadasa H, Lao Y, Krokhin O, Mookherjee N

Methods in molecular biology (Clifton, N.J.)2022

DOI: 10.1007/978-1-0716-2124-0_4 PMID: 35612734

07

Sequence-Specific Model for Predicting Peptide Collision Cross Section Values in Proteomic Ion Mobility Spectrometry.

Chang CH, Yeung D, Spicer V, Ogata K, Krokhin O, Ishihama Y

Journal of proteome research2021

DOI: 10.1021/acs.jproteome.1c00185 PMID: 34133192

08

Retention Time Prediction for Glycopeptides in Reversed-Phase Chromatography for Glycoproteomic Applications.

Ang E, Neustaeter H, Spicer V, Perreault H, Krokhin O

Analytical chemistry2019Senior author

DOI: 10.1021/acs.analchem.9b02584 PMID: 31566965

09

The proteome of extracellular vesicles released by clastic cells differs based on their substrate.

Rody WJ, Chamberlain CA, Emory-Carter AK, McHugh KP, Wallet SM, Spicer V, Krokhin O, Holliday LS

PloS one2019

DOI: 10.1371/journal.pone.0219602 PMID: 31291376

10

Absolute Quantitation of Glycoforms of Two Human IgG Subclasses Using Synthetic Fc Peptides and Glycopeptides.

Roy R, Ang E, Komatsu E, Domalaon R, Bosseboeuf A, Harb J, Hermouet S, Krokhin O, Schweizer F, Perreault H

Journal of the American Society for Mass Spectrometry2018

DOI: 10.1007/s13361-018-1900-7 PMID: 29796736

Cigarette smoking as a modifiable risk factor for Rheumatoid Arthritis development in First Nations Peoples.

Co-investigatorCIHR2026Project Grant

Principal investigators: O'Neil, Liam J

Keywords: Cigarette Smoking; Citrullination; Disease Risk; First Nations; Neutrophil Extracellular Traps; Preclinical; Proteomics; Rheumatoid Arthritis

$914,176

Cigarette smoking induced neutrophilic inflammation as a modifiable risk factor for Rheumatoid Arthritis in First Nations

Co-investigatorCIHR2024Project Grant - PA: Research in First Nations, Inuit and/or Métis Health

Principal investigators: O'Neil, Liam J

Keywords: Autoantibody; Cigarette Smoking; Citrullination; Collagen Induced Arthritis; First Nations; Neutrophil Extracellular Traps; Neutrophils; Proteomics; Rheumatoid Arthritis; Smoking Cessation

$100,000