This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Manitoba directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity.
Molecular metabolism · 2024
The Antioxidant Activity of Recombinant Rat Hepatic Fatty Acid Binding Protein T94A Variant.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2018
Latest funding
- $592,876
Improving therapeutic outcomes in medulloblastoma through optimizing brain delivery of agents targeting inhibitors of apoptosis proteins
CIHR · 2024 · Co-investigator
- $80,000
The molecular mechanisms by which functional nucleic acids modulate gene expression and epigenetic modifications
NSERC · 2023 · Principal investigator
- $250,000
Targeted inhibition of DNA methyltransferase
SSHRC · 2021 · Principal investigator
2 publications.
Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity.
Chen L, Li L, Cui D, Huang Y, Tong H, Zabihi H, Wang S, Qi Y, Lakowski T, Leng L, Liu S, Wu H, Young LH, Bucala R, Qi D
The Antioxidant Activity of Recombinant Rat Hepatic Fatty Acid Binding Protein T94A Variant.
Le T, Gong Y, Davies NM, Lillico R, Lakowski T, Roberts MS, Burczynski FJ
Improving therapeutic outcomes in medulloblastoma through optimizing brain delivery of agents targeting inhibitors of apoptosis proteins
Principal investigators: Miller, Donald W
Keywords: Blood-Brain Barrier; Cadherin Binding Peptides; Chemotherapy; Drug Delivery; Inhibitors Of Apoptosis Proteins; Medulloblastoma; Optical Imaging; Permeability Modulators; Radiation Therapy
The molecular mechanisms by which functional nucleic acids modulate gene expression and epigenetic modifications
Principal investigators: Lakowski, Ted
Keywords: Aptamers; DNA and RNA modifications; Enzymology; Epigenetics; Functional nucleic acids; Gene expression; histone post-translational modifications; Liquid chromatography tandem mass spectrometry LC-MS/MS; lncRNA; Lysine methyltransferases
Targeted inhibition of DNA methyltransferase
Principal investigators: Lakowski, Ted
Keywords: Drug discovery Medicinal chemistry Biologic drugs Epigenetics Mass Spectrometry Gene expression Nanoparticle drug delivery DNA methylation Aptamers Gene and molecular therapy
Oligonucleotide-bioconjugate mediated repression of the HOXA9 gene to treat mixed-lineage leukemia
Principal investigators: Lakowski, Ted M
Keywords: Drug Bio-Conjugation; Drug Development; Drug Discovery; Drug Targeting; Epigenetics; Histone Lysine Methyltransferase; Liquid Chromatography Tandem Mass Spectrometry; Post Translational Modifications
Development and clinical assessment of novel biomarker drugs targeting SSAT1 for detection and therapeutic monitoring of glioblastoma
Principal investigators: Miller, Donald W; Maula Bux, Rashid A; Klonisch, Thomas; Lakowski, Ted M
Keywords: Biomarker; Blood-Brain Barrier; Drug Acetylation; Early Detection; Glioblastoma; Metabolomics; Spermine Spermidine Acetyl Transferase 1; Therapeutic Monitoring
The mechanisms of enzymes catalyzing epigenetic post-translational modifications
Principal investigators: Lakowski, Ted
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- College of Pharmacy
- Biomedical Sciences
- Pharmacy
Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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