Amitabh Jha, Acadia University

Research

Read how they describe their research on their Acadia University profile.

Latest papers

Concise Synthesis of Naphthalene-Based 14-Aza-12-Oxasteroids.
Molecules (Basel, Switzerland) · 2025 · senior author
Conducting polymer-based scaffolds for neuronal tissue engineering.
Journal of materials chemistry. B · 2023
Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides.
Molecules (Basel, Switzerland) · 2019

All 21 publications

Latest funding

Naphthalene-based heterosteroidal molecules
NSERC · 2017 · Principal investigator
$70,000
High-Resolution Tandem Mass Spectrometer for Small Molecule and Bioanalysis Research
NSERC · 2016 · Co-investigator
$150,000
Expediting Drug Development by Profiling Novel Antineoplastics by Mass Spectrometry-based Biomarker Profiling
NSERC · 2016 · Principal investigator
$25,000

All 12 grants and awards

21 publications.

01

Concise Synthesis of Naphthalene-Based 14-Aza-12-Oxasteroids.

Srivastava S, Luo J, Whalen D, Robertson KN, Jha A

Molecules (Basel, Switzerland)2025Senior author

DOI: 10.3390/molecules30020415 PMID: 39860282

02

Conducting polymer-based scaffolds for neuronal tissue engineering.

Yi H, Patel R, Patel KD, Bouchard LS, Jha A, Perriman AW, Patel M

Journal of materials chemistry. B2023

DOI: 10.1039/d3tb01838e PMID: 37953707

03

Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides.

Yadav Y, Sharma D, Kaushik K, Kumar V, Jha A, Prasad AK, Len C, Malhotra SV, Wengel J, Parmar VS

Molecules (Basel, Switzerland)2019

DOI: 10.3390/molecules24213922 PMID: 31671703

04

Kinase-targeted cancer therapies: progress, challenges and future directions

Khushwant Singh Bhullar, Naiara Orrego Lagarón, Eileen M. McGowan, Indu Parmar, Amitabh Jha, Basil P. Hubbard, H.P. Vasantha Rupasinghe

Molecular Cancer20181,336 citationsOpen Access

DOI: 10.1186/s12943-018-0804-2 PMID: 29455673

05

Curcumin: Not So Spicy After All.

Jha A, Mohapatra PP, AlHarbi SA, Jahan N

Mini reviews in medicinal chemistry2017First author

DOI: 10.2174/1389557517666170228114234 PMID: 28245778

06

Convenient access to 5-arylisoindolo[2,1- α]quinolin-11(6a H)-ones.

O'Brien M, Weagle R, Corkum D, Kuanar M, Mohapatra PP, Jha A

Molecular diversity2017Senior author

DOI: 10.1007/s11030-016-9718-3 PMID: 28058523

07

Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells

Khushwant Singh Bhullar, Amitabh Jha, H.P. Vasantha Rupasinghe

Chemico-Biological Interactions201540 citations

DOI: 10.1016/j.cbi.2015.09.020 PMID: 26409325

08

Curcumin-inspired cytotoxic 3,5-bis(arylmethylene)-1-(N-(ortho-substituted aryl)maleamoyl)-4-piperidones: A novel group of topoisomerase II alpha inhibitors

Amitabh Jha, Katherine M. Duffield, Matthew R Ness, Sujatha Ravoori, Gabrielle Andrews, Khushwant Singh Bhullar, H.P. Vasantha Rupasinghe, Jan Balzarini

Bioorganic & Medicinal Chemistry201521 citationsFirst author

DOI: 10.1016/j.bmc.2015.08.023 PMID: 26456623

09

Concise synthesis of 12a-methyl-11-aryl-1,2-dihydrobenzo[f]pyrrolo[1,2-a]quinolin-3(12aH)-ones as racemic 14-azaestrogen analogs.

Abdelkhalik AM, Paul NK, Jha A

Steroids2015Senior author

DOI: 10.1016/j.steroids.2015.03.010 PMID: 25804763

10

All trans 1-(3-arylacryloyl)-3,5-bis(pyridin-4-ylmethylene)piperidin-4-ones as curcumin-inspired antineoplastics

Nawal K. Paul, Mamta Jha, Khushwant Singh Bhullar, H.P. Vasantha Rupasinghe, Jan Balzarini, Amitabh Jha

European Journal of Medicinal Chemistry201419 citationsSenior author

DOI: 10.1016/j.ejmech.2014.09.090 PMID: 25282269

Naphthalene-based heterosteroidal molecules

Principal investigatorNSERC2017Collaborative Research and Development Grants

Principal investigators: Jha, Amitabh

$70,000

High-Resolution Tandem Mass Spectrometer for Small Molecule and Bioanalysis Research

Co-investigatorNSERC2016Research Tools and Instruments

Principal investigators: Thompson, Alison

$150,000

Expediting Drug Development by Profiling Novel Antineoplastics by Mass Spectrometry-based Biomarker Profiling

Principal investigatorNSERC2016Engage Grants Program

Principal investigators: Jha, Amitabh

$25,000

New Heterocyclic Architectures from Cascade Processes

Principal investigatorNSERC2015Discovery Development Grant

Principal investigators: Jha, Amitabh

$20,000

Molecular diversity from naphthalene nucleus

Principal investigatorNSERC2010Discovery Grants Program - Individual

Principal investigators: Jha, Amitabh

$150,000

An absorption-emission system for the evaluation of DNA photocleaving agents

Co-investigatorNSERC2007Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: McFarland, Sherri

$148,500

Imaging plate detector for charge density studies, powder diffraction and general service crystallography

Co-investigatorNSERC2006Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Cameron, Stanley

$149,686

ESI TOF mass spectrometer with high resolution and MALDI capabilities

Co-investigatorNSERC2006Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Thompson, Alison

$150,000

High performance liquid chromatography

Principal investigatorNSERC2006Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Jha, Amitabh

$110,920

Atlantic Region Magnetic Resonance Centre

Co-investigatorNSERC2006Major Facilities Access Grants

Principal investigators: Zwanziger, Josef

$306,900

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Frequent collaborators

Chemistry
Plant, Food, and Environmental Sciences
PFES
Biology
Other

Co-authors at Acadia University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Vasantha Rupasinghe

PFES

5 shared papers, latest 2018

H.P.Vasantha Rupasinghe

Plant, Food, and Environmental Sciences

5 shared papers, latest 2018

Catherine Too

Department of Biochemistry & Molecular Biology

2 shared papers, latest 2014

Anuraag Shrivastav

Biology

2 shared papers, latest 2010

Basil Hubbard

Faculty

1 shared papers, latest 2018

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mention

Subject: Prospective PhD student Dear Professor Jha, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Concise Synthesis of Naphthalene-Based 14-Aza-12-Oxasteroids." (2025), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

Amitabh Jha

Research

Latest papers

Latest funding

Concise Synthesis of Naphthalene-Based 14-Aza-12-Oxasteroids.

Conducting polymer-based scaffolds for neuronal tissue engineering.

Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides.

Kinase-targeted cancer therapies: progress, challenges and future directions

Curcumin: Not So Spicy After All.

Convenient access to 5-arylisoindolo[2,1- &#x3b1;]quinolin-11(6a H)-ones.

Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells

Curcumin-inspired cytotoxic 3,5-bis(arylmethylene)-1-(N-(ortho-substituted aryl)maleamoyl)-4-piperidones: A novel group of topoisomerase II alpha inhibitors

Concise synthesis of 12a-methyl-11-aryl-1,2-dihydrobenzo[f]pyrrolo[1,2-a]quinolin-3(12aH)-ones as racemic 14-azaestrogen analogs.

All trans 1-(3-arylacryloyl)-3,5-bis(pyridin-4-ylmethylene)piperidin-4-ones as curcumin-inspired antineoplastics

Naphthalene-based heterosteroidal molecules

High-Resolution Tandem Mass Spectrometer for Small Molecule and Bioanalysis Research

Expediting Drug Development by Profiling Novel Antineoplastics by Mass Spectrometry-based Biomarker Profiling

New Heterocyclic Architectures from Cascade Processes

Molecular diversity from naphthalene nucleus

An absorption-emission system for the evaluation of DNA photocleaving agents

Imaging plate detector for charge density studies, powder diffraction and general service crystallography

ESI TOF mass spectrometer with high resolution and MALDI capabilities

High performance liquid chromatography

Atlantic Region Magnetic Resonance Centre

Frequent collaborators

Vasantha Rupasinghe

H.P.Vasantha Rupasinghe

Catherine Too

Anuraag Shrivastav

Basil Hubbard

Convenient access to 5-arylisoindolo[2,1- α]quinolin-11(6a H)-ones.