Eileen Denovan-Wright, Dalhousie University

Research

Allosteric interactions Bimolecular Complementation Bioluminescence Energy Transfer Cannabinoid Receptor Cell signalling Dopamine Receptor Endocannabinoid Fluorescence Energy Transfer

Latest papers

Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents.
The American journal of psychiatry · 2023
Biomarkers in aggression.
Advances in clinical chemistry · 2019
Cannabinoid and lipid-mediated vasorelaxation in retinal microvasculature.
European journal of pharmacology · 2014

All 3 publications

Latest funding

Structure and function of Cannabinoid Receptor Heterodimers
NSERC · 2019 · Principal investigator
$252,000
The Serine Hydrolases: Positioned at the Axis of Endocannabinoid-Eicosanoid Signaling
CIHR · 2019 · Co-investigator
$623,476
Reducing the signs and symptoms of Huntingtons disease by manipulating endocannabinoid tone.
CIHR · 2012 · Supervisor

All 6 grants and awards

3 publications.

01

Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents.

Zwicker A, Fullerton JM, Mullins N, Rice F, Hafeman DM, van Haren NEM, Setiaman N, Merranko JA, Goldstein BI, Ferrera AG, Stapp EK, de la Serna E, Moreno D, Sugranyes G, Herrero SM, Roberts G, Toma C, Schofield PR, Edenberg HJ, Wilcox HC, McInnis MG, Powell V, Propper L, Denovan-Wright E, Rouleau G, Castro-Fornieles J, Hillegers MHJ, Birmaher B, Thapar A, Mitchell PB, Lewis CM, Alda M, Nurnberger JI, Uher R

The American journal of psychiatry2023

DOI: 10.1176/appi.ajp.20220476 PMID: 36856707

02

Biomarkers in aggression.

Manchia M, Comai S, Pinna M, Pinna F, Fanos V, Denovan-Wright E, Carpiniello B

Advances in clinical chemistry2019

DOI: 10.1016/bs.acc.2019.07.004 PMID: 31655730

03

Cannabinoid and lipid-mediated vasorelaxation in retinal microvasculature.

MacIntyre J, Dong A, Straiker A, Zhu J, Howlett SE, Bagher A, Denovan-Wright E, Yu DY, Kelly ME

European journal of pharmacology2014

DOI: 10.1016/j.ejphar.2014.03.055 PMID: 24751709

Structure and function of Cannabinoid Receptor Heterodimers

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Denovan-Wright, Eileen

Keywords: Allosteric interactions; Bimolecular Complementation; Bioluminescence Energy Transfer; Cannabinoid Receptor; Cell signalling; Dopamine Receptor; Endocannabinoid; Fluorescence Energy Transfer; Functional selectivity; Ligand bias

$252,000

The Serine Hydrolases: Positioned at the Axis of Endocannabinoid-Eicosanoid Signaling

Co-investigatorCIHR2019Project Grant

Principal investigators: Kelly, Melanie E

Keywords: Alpha Beta Hydroxylase Domain 6; Alpha/Beta Hydroxylase Domain 12; Central Nervous System; Eicosanoid; Endocannabinoid System; Monoacyl Glycerol Lipase; Neurodegeneration; Neuroinflammation; Retina; Serine Hydrolases

$623,476

Reducing the signs and symptoms of Huntingtons disease by manipulating endocannabinoid tone.

SupervisorCIHR2012Doctoral Research Award - Priority Announcement: Huntington Disease

Principal investigators: Laprairie, Robert B

Keywords: Cannabinoids; Cell Culture; Huntington'S Disease; Pharmacology; Substance Abuse/Addiction; Transgenic Animal Model

Regulation of type 1 cannabinoid receptor expression in Huntington's disease.

SupervisorCIHR2011Master's Award: Canada Graduate Scholarships

Principal investigators: Laprairie, Robert B

Keywords: Biochemistry; Cell Culture; Endocannabinoid System; Gene Expression; Huntington'S Disease; Neurodevelopment; Neuroscience; Pharmacology

$17,500

Regulation of transcription in Huntington's Disease

Nominated PICIHR2008CIHR/Regional Partnership Program/Operating Grants

Principal investigators: Denovan-Wright, Eileen M

Keywords: Gene Expression; Gene Regulation; Huntington'S Disease; In Vitro Transcription; Neuronal Cell Culture; Protein-Protein Interactions

$171,543

Liquid scintillation counter

Co-investigatorNSERC2003Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Blay, Jonathan

$51,144

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Psychiatry
Pharmacology
Neurology and Neurosurgery

Co-authors at Dalhousie University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Rudolf Uher

Psychiatry

1 shared papers, latest 2023

Martin Alda

Psychiatry

1 shared papers, latest 2023

Guy Rouleau

Neurology and Neurosurgery

1 shared papers, latest 2023

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their NSERC grant from 2019

Subject: Prospective PhD student: Allosteric interactions Dear Professor Denovan-Wright, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Polygenic Scores and Onset of Major Mood or Psychotic Disorders Among Offspring of Affected Parents." (2023), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your NSERC-funded project "Structure and function of Cannabinoid Receptor Heterodimers" (2019), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]