Faculty profile

Guy Rouleau

ResearcherNeurology and NeurosurgeryMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Guy Rouleau

Researcher

Neurology and Neurosurgery

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
27 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 20 research grants (20 CIHR), most recently in 2026.
Supervisor on 19 trainee awards (19 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Genetics Amyotrophic Lateral Sclerosis Gene Silencing Huntington Disease Machado-Joseph Disease Neurogenerative Disease Oculopharyngeal Muscular Dystrophy Pseudoknot

Latest papers

The role of dentists in the recognition of neurodegenerative and systemic conditions with neurological involvement.
Oral surgery, oral medicine, oral pathology and oral radiology · 2026 · senior author
DNA methylation signatures associated with bipolar disorder in peripheral blood improve prediction models.
EBioMedicine · 2026
Whole-exome sequencing in individuals with obsessive-compulsive disorder and chronic tic disorders identifies 36 large-effect risk genes.
Nature neuroscience · 2026

All 75 publications

Latest funding

Cellular phenotypes of bipolar disorder and its response to treatment
CIHR · 2026 · Principal investigator
$948,600
The role of C9orf72 in cerebellar function and movement disorders
CIHR · 2025 · Co-investigator
$1,105,426
Leveraging cohort-scale single-cell RNA sequencing analysis of stem cell-derived dopaminergic neurons to identify genetic determinants of Parkinson's disease using an interpretable machine learning classification framework.
CIHR · 2024 · Supervisor
$120,000

All 49 grants and awards

75 publications.

The role of dentists in the recognition of neurodegenerative and systemic conditions with neurological involvement.

Herrero Babiloni A, Dal Fabbro C, Samin F, Schmittbuhl M, Blanchet PJ, Lavigne GJ, Rouleau G

Oral surgery, oral medicine, oral pathology and oral radiology2026Senior author

DOI: 10.1016/j.oooo.2026.01.010 PMID: 41741312

DNA methylation signatures associated with bipolar disorder in peripheral blood improve prediction models.

Tesfaye M, Stavrum AK, Höffler KD, O'Connell KS, David FS, Garrett ME, Hesam-Shariati S, Overs BJ, Pisanu C, Spano L, Watkeys OJ, Weihs A, Ardau R, Ashley-Koch AE, Athanasiu L, Beckham JC, Bourassa KJ, Chillotti C, Djurovic S, Drange OK, Frank J, Khayachi A, Kimbrel NA, Martorell L, Meinert S, Melle I, Morken G, Paribello P, Pinna M, Roberts G, Rouleau G, Schofield PR, Sepúlveda E, Severino G, Steen VM, Stein F, Streit F, VA Mid-Atlantic MIRECC Workgroup, Lagerberg TV, Alda M, Dannlowski U, Forstner AJ, Fullerton JM, Grabe HJ, Green MJ, Kircher T, Labad J, Manchia M, Mitchell PB, Soares JC, Squassina A, Teumer A, Tondo L, Vilella E, Andreassen OA, Chaumette B, Fries GR, Le Hellard S

EBioMedicine2026

DOI: 10.1016/j.ebiom.2026.106284 PMID: 42105630

Whole-exome sequencing in individuals with obsessive-compulsive disorder and chronic tic disorders identifies 36 large-effect risk genes.

Wang B, Tran MN, Wang S, Liu Y, Olfson E, Wang G, Sun N, Dea J, Olwal CO, Bertolace L, Bloch MH, Cappi C, Chang YC, Chavira D, Coffey BJ, Falkenstein MJ, Frank AC, Franklin ME, Garayalde S, Garrido H, Grados M, Hatem R, Howell AL, Khim S, Kuckertz JM, Le MM, Libby A, McCarty RJ, McNamara ME, McNeil D, Miguel EC, Nasello C, Nguyen B, Norbu T, Oh L, Ordway A, Paciotti C, Peskin VA, Pittenger C, Simpson HB, Simpson Martin H, Tischfield MA, Xing J, Zakrzewski JJ, Tourette International Collaborative Genetics (TIC Genetics), Dietrich A, Gilbert DL, Hoekstra PJ, Kim YS, Kuperman S, Rosen A, Zinner SH, Bouhaddou M, King RA, Rouleau G, Ressler KJ, Mathews CA, Krogan NJ, Sestan N, Tischfield JA, Lee AM, Heiman GA, Fernandez TV, Willsey AJ, State MW

Nature neuroscience2026

DOI: 10.1038/s41593-026-02419-5 PMID: 42680906

The Genetic and Molecular Analyses of Rare Candidate Germline BRIP1/FANCJ Variants Implicated in Hereditary Breast and Ovarian Cancers.

Alenezi WM, Milano L, Fierheller CT, Serruya C, Revil T, Oros KK, Bruce JP, Spiegelman D, Pugh T, Mes-Masson AM, Provencher D, Foulkes WD, El Haffaf Z, Rouleau G, Bouchard L, Greenwood CMT, Ragoussis J, Masson JY, Tonin PN

International journal of molecular sciences2026

DOI: 10.3390/ijms27021037 PMID: 41596682

Ancestry-specific and multi-ancestry genome-wide association studies of restless legs syndrome.

Akçimen F, Medeiros M, Cederberg KLJ, Khani M, Roth A, Nalls MA, Bandres-Ciga S, Dion PA, Rouleau G, Mignot E

medRxiv : the preprint server for health sciences2026

DOI: 10.64898/2026.04.28.26351960 PMID: 42145650

Rare coding mutations identify 36 large-effect risk genes in obsessive-compulsive disorder and chronic tic disorders.

Wang B, Tran MN, Wang S, Liu Y, Olfson E, Wang G, Sun N, Dea J, Olwal CO, Bertolace L, Bloch MH, Cappi C, Chang YC, Chavira D, Coffey BJ, Falkenstein MJ, Frank AC, Franklin ME, Garayalde S, Garrido H, Grados M, Hatem R, Howell AL, Khim S, Kuckertz JM, Le MM, Libby A, McCarty RJ, McNamara ME, McNeil D, Miguel EC, Nasello C, Nguyen B, Norbu T, Oh L, Ordway A, Paciotti C, Peskin VA, Pittenger C, Simpson HB, Martin HS, Tischfield MA, Xing J, Zakrzewski JJ, Tourette International Collaborative Genetics (TIC Genetics), Dietrich A, Gilbert DL, Hoekstra PJ, Kim YS, Kuperman S, Rosen A, Zinner SH, Bouhaddou M, King RA, Rouleau G, Ressler KJ, Mathews CA, Krogan NJ, Sestan N, Tischfield JA, Lee AM, Heiman GA, Fernandez TV, Willsey AJ, State MW

medRxiv : the preprint server for health sciences2025

DOI: 10.1101/2025.10.10.25337672 PMID: 41282685

MRI-derived atrophy in multiple system atrophy aligns with mitochondrial and glial gene expression patterns.

Chougar L, Tremblay C, Delva A, Filiatrault M, Vo A, Hansen JY, Farahani A, Misic B, Khalafi P, Castonguay CE, Rouleau G, Corvol JC, Vidailhet M, Degos B, Pyatigorskaya N, Payan C, Grabli D, Lehéricy S, Dagher A, Rahayel S

NPJ Parkinson's disease2025

DOI: 10.1038/s41531-025-01227-1 PMID: 41453978

Hereditary Spastic Paraplegia in Alberta: Lessons from a Well-Defined Cohort Including the Indigenous Population.

Assaedi E, Ashtiani S, Estiar MA, Gan-Or Z, McKenzie ED, Shetty A, Rouleau G, Suchowersky O

Movement disorders clinical practice2025

DOI: 10.1002/mdc3.70115 PMID: 40322871

Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism.

Hengel H, Hannan SB, Reich S, Beijer D, Roller J, Gilsbach BK, Gloeckner CJ, Greene D, Timmann D, Depienne C, Mumford A, O'Driscoll M, Nemeth AH, Lundberg J, Rodan LH, Bruel AL, Delanne J, Deconinck T, Baets J, Gan-Or Z, Rouleau G, Suchowersky O, Estiar MA, Reich S, Toro C, Züchner S, Hazan J, Pétursson H, Harmuth F, Bauer C, Bauer P, Turro E, Lambright D, Schöls L, Synofzik M

Brain : a journal of neurology2025

DOI: 10.1093/brain/awaf111 PMID: 40166812

Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations.

Soubannier V, Chaineau M, Gursu L, Lépine S, Kalaydjian D, Sirois J, Haghi G, Rouleau G, Durcan TM, Stifani S

Glia2024

DOI: 10.1002/glia.24598 PMID: 39092466

Something wrong or missing on this profile? Suggest a correction

Guy Rouleau

Research

Latest papers

Latest funding

The role of dentists in the recognition of neurodegenerative and systemic conditions with neurological involvement.

DNA methylation signatures associated with bipolar disorder in peripheral blood improve prediction models.

Whole-exome sequencing in individuals with obsessive-compulsive disorder and chronic tic disorders identifies 36 large-effect risk genes.

The Genetic and Molecular Analyses of Rare Candidate Germline BRIP1/FANCJ Variants Implicated in Hereditary Breast and Ovarian Cancers.

Ancestry-specific and multi-ancestry genome-wide association studies of restless legs syndrome.

Rare coding mutations identify 36 large-effect risk genes in obsessive-compulsive disorder and chronic tic disorders.

MRI-derived atrophy in multiple system atrophy aligns with mitochondrial and glial gene expression patterns.

Hereditary Spastic Paraplegia in Alberta: Lessons from a Well-Defined Cohort Including the Indigenous Population.

Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism.

Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations.

Frequent collaborators

Martin Alda

Bernard Brais

Ridha Joober

Gustavo Turecki

Luigi Bouchard

Myriam Srour

Alain Dagher

Anne-Marie Mes-Masson

Aly Karsan

Stefano Stifani

Abraham Nunes

Thomas Trappenberg

Roberta La Piana

Cecilia Flores

Guillaume Bourque

Michel Boivin

Paul Sandor

Trevor Pugh

Ginette Dionne

Alain Lesage

Sirui Zhou

Mark Tarnopolsky

Frank Vitaro

Rudolf Uher

Isabelle Ouellet-Morin

Jean-Yves Masson

Amit Bar-Or

Emmanuel Bujold

Mark Walker

Gabriella Gobbi

Paul Pavlidis

Serge Gauthier

Sarojini Sengupta