Faculty profile

Jean-François Legare

ResearcherMicrobiology and ImmunologyDalhousie University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Dalhousie University directory, so their courses and email address may be missing. Find their university profile.

Jean-François Legare

Researcher

Microbiology and Immunology

Health Sciences

Dalhousie University

Halifax, Nova Scotia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
5 publications in the last five years, latest in 2026.
Principal investigator on 4 research grants (4 CIHR), most recently in 2013.
Supervised 2 trainees who won CIHR awards, most recently in 2017.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Arthritis Cell Migration Chemokines Heart Disease Immunology Inflammation Mast Cells

Latest papers

Contemporary surgical outcomes and repair rates in degenerative mitral regurgitation: Real-world insights from the international MITRACURE registry.
The Journal of thoracic and cardiovascular surgery · 2026
Clinical Presentation and Outcomes After Surgery for Mitral Regurgitation: Real-World Insights From the MITRACURE International Registry.
Circulation · 2025
Commentary: Post operative atrial fibrillation: Out of sight out of mind.
The Journal of thoracic and cardiovascular surgery · 2023 · first author

All 24 publications

Latest funding

Mast cells as regulators of inflammation in heart failure
CIHR · 2017 · Supervisor
$105,000
Restitution Enhancement in Arthritis and Chronic Heart disease
CIHR · 2013 · Principal investigator
$2,337,154
Characterizing the monocytic origins of fibroblast progenitor cells and how we can use this information for myocardial therapies
CIHR · 2012 · Supervisor
$70,000

All 7 grants and awards

24 publications.

Contemporary surgical outcomes and repair rates in degenerative mitral regurgitation: Real-world insights from the international MITRACURE registry.

Bouchard D, Dreyfus J, Tourneau TL, Ternacle J, Pellerin M, Guo L, Fu AYN, Dib JC, Luong C, Sokolov T, Anselmi A, Tchétché D, Meslin OB, Bouchot O, Lavie-Badie Y, Seknadji P, Coisne A, Arangalage D, Bernard A, Manian U, Kass M, Fiore A, Maudiere A, Bohbot Y, Seemann A, Hammoudi N, Bière L, Leroux PY, Forcillo J, Jeu A, Elegamandji B, Huttin O, Gilard M, Bouleti C, Harnett DT, Legare JF, Moussi TS, Ye J, Sportouch C, Bittira B, Munte L, Bauer F, Leong-Poi H, Hassanabad AF, Modine T, Suc G, Bernick J, Wells GA, Gauda R, Dan AA, Iung B, Kent W, Obadia JF, Chu MWA, Messika-Zeitoun D, MITRACURE Investigators

The Journal of thoracic and cardiovascular surgery2026

DOI: 10.1016/j.jtcvs.2026.03.605 PMID: 42092496

Clinical Presentation and Outcomes After Surgery for Mitral Regurgitation: Real-World Insights From the MITRACURE International Registry.

Messika-Zeitoun D, Chu MWA, Bouchard D, Le Tourneau T, Ternacle J, Demers P, Guo L, Fu AYN, Dib JC, Lam C, Sokolov T, Anselmi A, Tchétché D, Brault Meslin O, Goutondji A, Lavie-Badie Y, Seknadji P, Coisne A, Arangalage D, Bernard A, Manian U, Kass M, Fiore A, Maudiere A, Bohbot Y, Seemann A, Hammoudi N, Bière L, Leroux PY, Forcillo J, Jeu A, Elegamandji B, Selton-Suty C, Gilard M, Bouleti C, Arshad O, Legare JF, Si Moussi T, Ye J, Sportouch C, Bittira B, Munte L, Bauer F, Ong G, Fatehi Hassanabad A, Bernick J, Wells GA, Gauda R, Iung B, Kent WDT, Obadia JF, Dreyfus J, MITRACURE Investigators

Circulation2025

DOI: 10.1161/circulationaha.124.073674 PMID: 40886109

Commentary: Post operative atrial fibrillation: Out of sight out of mind.

Legare JF

The Journal of thoracic and cardiovascular surgery2023First author

DOI: 10.1016/j.jtcvs.2021.11.029 PMID: 34893328

Commentary: Are we really choosing between less delirium or better quality of life when comparing transcatheter aortic valve implantation with surgical aortic valve replacement?

Legare JF

The Journal of thoracic and cardiovascular surgery2023First author

DOI: 10.1016/j.jtcvs.2021.11.046 PMID: 34895727

A National Strategy to Detect and Treat Heart Valve Diseases in Canada

Forcillo J, Wood DA, Abdel-Razek O, Adreak N, Asgar A, Chedrawy E, Eckstein J, Legare J-F, Natarajan MK, Pibarot P

Canadian Journal of Cardiology20235 citations

DOI: 10.1016/j.cjca.2023.01.021 PMID: W4318305512

Cardiac surgeons' concerns, perceptions, and responses during the COVID-19 pandemic.

Luc JGY, Ad N, Nguyen TC, COVID-19 North American Cardiac Surgery Survey Working Group Collaborators, Arora RC, Balkhy HH, Bender EM, Bethencourt DM, Bisleri G, Boyd D, Chu MWA, de la Cruz KI, DeAnda A, Engelman DT, Farkas EA, Fedoruk LM, Fiocco M, Forcillo J, Fradet G, Fremes SE, Gammie JS, Geirsson A, Gerdisch MW, Girard LN, Kaiser CA, Kaneko T, Kent WDT, Khabbaz KR, Khoynezhad A, Kiaii B, Lee R, Legare JF, Lehr EJ, MacArthur RGG, McCarthy PM, Mehall JR, Merrill WH, Moon MR, Ouzounian M, Peltz M, Perrault LP, Preventza O, Ramchandani M, Ramlawi B, Salenger R, Sekela ME, Sellke FW, Stulak JM, Sutter FP, Timek TA, Whitman G, Williams JB, Wong DR, Yanagawa B, Ye J, Zeigler SM

Journal of cardiac surgery2021

DOI: 10.1111/jocs.15681 PMID: 34118080

Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery.

Aguiar CM, Gawdat K, Legere S, Marshall J, Hassan A, Kienesberger PC, Pulinilkunnil T, Castonguay M, Brunt KR, Legare JF

Journal of translational medicine2019Senior author

DOI: 10.1186/s12967-019-02162-5 PMID: 31822289

Validation of optimal reference genes for quantitative real time PCR in muscle and adipose tissue for obesity and diabetes research.

Perez LJ, Rios L, Trivedi P, D'Souza K, Cowie A, Nzirorera C, Webster D, Brunt K, Legare JF, Hassan A, Kienesberger PC, Pulinilkunnil T

Scientific reports2017

DOI: 10.1038/s41598-017-03730-9 PMID: 28620170

Cardiac troponin T is an important predictor of mortality after cardiac surgery.

Mokhtar AT, Begum J, Buth KJ, Legare JF

Journal of critical care2017Senior author

DOI: 10.1016/j.jcrc.2016.10.011 PMID: 27837691

Changes in Circulating Monocyte Subsets (CD16 Expression) and Neutrophil-to-Lymphocyte Ratio Observed in Patients Undergoing Cardiac Surgery.

Gawdat K, Legere S, Wong C, Myers T, Marshall JS, Hassan A, Brunt KR, Kienesberger PC, Pulinilkunnil T, Legare JF

Frontiers in cardiovascular medicine2017Senior author

DOI: 10.3389/fcvm.2017.00012 PMID: 28361055

Mast cells as regulators of inflammation in heart failure

SupervisorCIHR2017Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Legere, Stephanie A

Keywords: Cardiovascular Disease; Fibrosis; Heart Failure; Immunology; Inflammation; Interleukin-33; Mast Cells; Myocardial Infarction

$105,000

Restitution Enhancement in Arthritis and Chronic Heart disease

Principal investigatorCIHR2013Team Grant: Health Challenges in Chronic Inflammation Initiative - (Full Appl)

Principal investigators: Marshall, Jean S; Bezuhly, Michael; Eklund, Kari K; Hanly, John G; Issekutz, Thomas B; Johnston, Brent; Legare, Jean-François; Lin, Tong-Jun; McDougall, Jason J

Keywords: Arthritis; Cell Migration; Chemokines; Heart Disease; Immunology; Inflammation; Mast Cells

$2,337,154

Characterizing the monocytic origins of fibroblast progenitor cells and how we can use this information for myocardial therapies

SupervisorCIHR2012Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Falkenham, Alec G

Keywords: Cell Culture; Cell Sorting; Fibrocytes; Fibrosis; Flow Cytometry; Heart Failure; Immunofluorescence; Liposomes; Monocytes

$70,000

Restitution enhancement in arthritis and chronic heart disease

Principal investigatorCIHR2012Team Grant: Health Challenges in Chronic Inflammation Initiative (LOI)

Principal investigators: Marshall, Jean S; Bezuhly, Michael; Legare, Jean-François; Lin, Tong-Jun; McDougall, Jason J

Keywords: Arthritis; Cell Migration; Chemokines; Heart Disease; Immunology; Inflammation; Mast Cells

$18,920

Cardiac Surgery in The Frail and Elderly; Towards optimal decision making in a vulnerable population.

Co-investigatorCIHR2011Operating Grant

Principal investigators: Hirsch, Gregory M

Keywords: Anxiety; Cardiac Surgery; Health Services Delivery; Informed Consent; Patient Centredness; Shared Decision Making; Vulnerable Populations

$281,422

Connective Tissue Growth Factor and fibrocyte recruitment to the myocardium

Nominated PICIHR2010Operating Grant -PA: Inst of Circulatory and Respiratory Health - Bridge Funding

Principal investigators: Legare, Jean-François

Keywords: Cardiomyocyte; Collagen; Ctgf; Fibroblast; Fibrocytes; Fibrosis; Heart Failure; Tgfbeta

$79,310

Connective Tissue Growth Factor and fibrocyte recruitment to the myocardium

Nominated PICIHR2010Operating Grant - PA: Regional Partnership Program - Nova Scotia

Principal investigators: Legare, Jean-François

Keywords: Cardiomyocyte; Collagen; Ctgf; Fibroblast; Fibrocytes; Fibrosis; Heart Failure; Tgfbeta

$79,310

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Jean-François Legare

Research

Latest papers

Latest funding

Contemporary surgical outcomes and repair rates in degenerative mitral regurgitation: Real-world insights from the international MITRACURE registry.

Clinical Presentation and Outcomes After Surgery for Mitral Regurgitation: Real-World Insights From the MITRACURE International Registry.

Commentary: Post operative atrial fibrillation: Out of sight out of mind.

Commentary: Are we really choosing between less delirium or better quality of life when comparing transcatheter aortic valve implantation with surgical aortic valve replacement?

A National Strategy to Detect and Treat Heart Valve Diseases in Canada

Cardiac surgeons' concerns, perceptions, and responses during the COVID-19 pandemic.

Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery.

Validation of optimal reference genes for quantitative real time PCR in muscle and adipose tissue for obesity and diabetes research.

Cardiac troponin T is an important predictor of mortality after cardiac surgery.

Changes in Circulating Monocyte Subsets (CD16 Expression) and Neutrophil-to-Lymphocyte Ratio Observed in Patients Undergoing Cardiac Surgery.

Mast cells as regulators of inflammation in heart failure

Restitution Enhancement in Arthritis and Chronic Heart disease

Characterizing the monocytic origins of fibroblast progenitor cells and how we can use this information for myocardial therapies

Restitution enhancement in arthritis and chronic heart disease

Cardiac Surgery in The Frail and Elderly; Towards optimal decision making in a vulnerable population.

Connective Tissue Growth Factor and fibrocyte recruitment to the myocardium

Connective Tissue Growth Factor and fibrocyte recruitment to the myocardium

Frequent collaborators

Thomas Pulinilkunnil

David Messika-Zeitoun

Bobby Yanagawa

Guy Fradet

Christina Luong

Mackenzie Quantz

Richard Whitlock

Salim Yusuf

Philip Devereaux

Andre Lamy

Madhu Natarajan

Emilie Belley-Cote

Harindra Wijeysundera

Howard Leong-Poi

Philippe Pibarot

Jean Marshall