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Research
Latest papers
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope.
Journal of lipid research · 2024
Autophagy enhances bacterial clearance during P. aeruginosa lung infection.
PloS one · 2013
Hypoxia-induced downregulation of autophagy mediator Beclin 1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis.
Autophagy · 2009 · senior author
Latest funding
- $100,000
Cystine/glutamate antiporter system xc- as a target for HER2-positive breast cancer treatment
CIHR · 2024 · Nominated PI
- $684,675
Molecular hallmarks of breast cancer sensitivity to ErbB2-targeted therapies
CIHR · 2017 · Nominated PI
- $187,395
Beta-catenin as a regulator of cancer cell survival
CIHR · 2012 · Nominated PI
5 publications.
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope.
McPhee M, Lee J, Salsman J, Pinelli M, Di Cara F, Rosen K, Dellaire G, Ridgway ND
Autophagy enhances bacterial clearance during P. aeruginosa lung infection.
Junkins RD, Shen A, Rosen K, McCormick C, Lin TJ
Hypoxia-induced downregulation of autophagy mediator Beclin 1 reduces the susceptibility of malignant intestinal epithelial cells to hypoxia-dependent apoptosis.
Yoo BH, Wu X, Derouet M, Haniff M, Eskelinen EL, Rosen K
Oncogenic Ras inhibits anoikis of intestinal epithelial cells by preventing the release of a mitochondrial pro-apoptotic protein Omi/HtrA2 into the cytoplasm.
Liu Z, Li H, Derouet M, Berezkin A, Sasazuki T, Shirasawa S, Rosen K
Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells.
Yan SR, Joseph RR, Rosen K, Reginato MJ, Jackson A, Allaire N, Brugge JS, Jobin C, Stadnyk AW
Cystine/glutamate antiporter system xc- as a target for HER2-positive breast cancer treatment
Principal investigators: Rosen, Kirill V
Keywords: Breast Cancer; Cancer Stem Cells; Cell Death; Erbb2/Her2; Ferroptosis
Molecular hallmarks of breast cancer sensitivity to ErbB2-targeted therapies
Principal investigators: Rosen, Kirill V
Keywords: Anoikis; Apoptosis; Biomarkers; Breast Cancer; Erbb2/Her2-Targeted Therapies; Extracellular Matrix; Lapatinib; Neoadjuvant Therapy; Trastuzumab
Beta-catenin as a regulator of cancer cell survival
Principal investigators: Rosen, Kirill V
Keywords: Anoikis; Apoptosis; Beta-Catenin; Cancer; Cell Signaling; Extracellular Matrix
Molecular mechanisms of apoptosis induced by the loss of cell-extracellular matrix adhesion
Principal investigators: Rosen, Kirill
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Microbiology and Immunology
- Pediatrics
- Pathology
Co-authors at Dalhousie University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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