Faculty profile

Graham Dellaire

ResearcherPathologyDalhousie University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Dalhousie University directory, so their courses may be missing. Find their university profile.

Graham Dellaire

Researcher

Pathology

Health Sciences

Dalhousie University

Halifax, Nova Scotia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
24 publications in the last five years, latest in 2026.
Senior (last) author on 8 recent papers, a sign of leading a research group.
Principal investigator on 12 research grants (6 CIHR, 6 NSERC), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Confocal Microscopy Proximity Proteomics Anoikis Breast And Cervical Cancer Chemotherapy Growth Factor Signaling Oxidative Stress Signaling Pre-Mrna Splicing

Latest papers

Epigenetic control of telomeric RNA maintains heterochromatin in telomerase-driven cancers.
Signal transduction and targeted therapy · 2026
Membrane curvature elastic stress triggers recruitment of PML-II onto the inner nuclear membrane.
Molecular biology of the cell · 2026
The evolutionarily conserved PRP4K-CHMP4B/vps32 splicing circuit regulates autophagy.
Cell reports · 2025 · senior author

All 96 publications

Latest funding

Determining how PRP4K insufficiency impacts cancer signaling and therapy responses
CIHR · 2023 · Nominated PI
$1,178,100
Characterizing the evolutionarily conserved functions of the pre-mRNA processing factor 4 kinase in cellular stress
CIHR · 2022 · Nominated PI
$100,000
Evolutionary molecular biology of the interplay between the DNA damage response and innate immunity
NSERC · 2020 · Principal investigator
$180,000

All 16 grants and awards

96 publications.

Epigenetic control of telomeric RNA maintains heterochromatin in telomerase-driven cancers.

Price JDW, Vizeacoumar FS, Abuhussein O, Maranda V, Zhang Y, Adachi H, Nguyen K, Kyrylenko L, Rangel-Pozzo A, Dong H, Gong L, Materi A, Walke P, Ganapathysamy A, Denomy C, Freywald T, Dahiya R, Elhasasna H, Saxena A, Vizeacoumar JP, Patel H, Rajamanickam K, de Oliveira DM, Lazell-Wright M, Morales AM, Aggarwal A, Xu JL, Alli N, Munhoz EP, Gao P, Salsman J, Dahiya DK, Kola NS, Gonzalez-Lopez C, Thibault P, Levin M, Dellaire G, Jette N, Groot G, Köbel M, Lee CH, Hopkins L, Krishnan A, Ahmed S, Eskiw C, Barakat KH, Thakur A, Wu Y, DePinho RA, Mai S, Yu YT, Wong JMY, Freywald A, Vizeacoumar FJ

Signal transduction and targeted therapy2026

DOI: 10.1038/s41392-026-02750-0 PMID: 42236690

Membrane curvature elastic stress triggers recruitment of PML-II onto the inner nuclear membrane.

McPhee M, Salsman J, Newman AA, Voutsina N, Crosby AH, Dellaire G, Ridgway ND

Molecular biology of the cell2026

DOI: 10.1091/mbc.e25-09-0443 PMID: 41370120

The evolutionarily conserved PRP4K-CHMP4B/vps32 splicing circuit regulates autophagy.

Mathavarajah S, Chipurupalli S, Habib EB, Kim WD, Aoki MM, Corkery DP, Whelan KIT, Lukacs J, Erkan M, Martinez VD, Smith KS, Montgomery SB, Salsman J, Huber RJ, Dellaire G

Cell reports2025Senior author

DOI: 10.1016/j.celrep.2025.115870 PMID: 40531620

The proximity interactome of PML isoforms I and II under fatty acid stress.

Thompson J, Boisvert FM, Salsman J, Lévesque D, Dellaire G, Ridgway ND

FEBS letters2025

DOI: 10.1002/1873-3468.15081 PMID: 39703998

Retraction Note: A mechanism for the suppression of homologous recombination in G1 cells.

Orthwein A, Noordermeer SM, Wilson MD, Landry S, Enchev RI, Sherker A, Munro M, Pinder J, Salsman J, Dellaire G, Xia B, Peter M, Durocher D

Nature2025

DOI: 10.1038/s41586-025-08644-5 PMID: 39870925

Telomeric SUMO level influences the choices of APB formation pathways and ALT efficiency.

Zhao R, Wivagg A, Lackner RM, Salsman J, Dellaire G, Matunis MJ, Chenoweth DM, Zhao X, Zhang H

bioRxiv : the preprint server for biology2025

DOI: 10.1101/2025.01.16.633463 PMID: 39896638

Telomeric SUMO level influences the choices of APB formation pathways and ALT efficiency.

Zhao R, Yu X, Chigumira T, Xu M, Wivagg A, Lackner RM, Salsman J, Dellaire G, Matunis MJ, Chenoweth DM, Zhao X, Zhang H

The Journal of cell biology2025

DOI: 10.1083/jcb.202410073 PMID: 40899993

From biosynthesis and beyond-Loss or overexpression of the cytokinin synthesis gene, iptA, alters cytokinesis and mitochondrial and amino acid metabolism in Dictyostelium discoideum.

Aoki MM, Kisiala AB, Mathavarajah S, Schincaglia A, Treverton J, Habib E, Dellaire G, Emery RJN, Brunetti CR, Huber RJ

FASEB journal : official publication of the Federation of American Societies for Experimental Biology2024

DOI: 10.1096/fj.202301936rr PMID: 38102957

Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope.

McPhee M, Lee J, Salsman J, Pinelli M, Di Cara F, Rosen K, Dellaire G, Ridgway ND

Journal of lipid research2024

DOI: 10.1016/j.jlr.2024.100540 PMID: 38570093

Mechanisms for assembly of the nucleoplasmic reticulum.

McPhee M, Dellaire G, Ridgway ND

Cellular and molecular life sciences : CMLS2024

DOI: 10.1007/s00018-024-05437-3 PMID: 39367888

Determining how PRP4K insufficiency impacts cancer signaling and therapy responses

Nominated PICIHR2023Project Grant

Principal investigators: Dellaire, Graham P

Keywords: Anoikis; Breast And Cervical Cancer; Chemotherapy; Confocal Microscopy; Growth Factor Signaling; Oxidative Stress Signaling; Pre-Mrna Splicing; Proximity Proteomics; Prp4k; Tissue Microarrays

$1,178,100

Characterizing the evolutionarily conserved functions of the pre-mRNA processing factor 4 kinase in cellular stress

Nominated PICIHR2022Project Grant

Principal investigators: Dellaire, Graham P

Keywords: Autophagy; Cell Stress Signaling; Confocal Microscopy; Dictyostelium Discoideum; Evolutionary Molecular Biology; Macropinocytosis; Nutrient And Oxidative Stress; Pre-Mrna Splicing Factor 4 Kinase (Prp4k); Proximity Proteomics; Taxanes

$100,000

Evolutionary molecular biology of the interplay between the DNA damage response and innate immunity

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Dellaire, Graham

$180,000

1st Canadian Environmental Exposures in Cancer (CE2C) Network Meeting

Nominated PICIHR2018Planning and Dissemination Grant - Institute Community Support

Principal investigators: Dellaire, Graham P; Lam, Wan L

Keywords: Arsenic; Cancer; Cancer Epidemiology; Cohort Studies; Environmental Exposures; Radon

$10,000

Super-resolution radial fluctuation microscope for 4D imaging of cells and cellular dynamics

Principal investigatorNSERC2018Research Tools and Instruments

Principal investigators: Dellaire, Graham

$86,118

Identifying the regulatory functions of nuclear lipid synthesis and storage pathways

Co-investigatorCIHR2018Project Grant

Principal investigators: Ridgway, Neale D

Keywords: Fluorescence Microscopy And Cell Imaging; Lipid Droplets; Nuclear Lipid Synthesis; Phospholipid Synthesis; Pml Bodies; Protein Phosphorylation; Triglyceride Synthesis

$730,575

Characterization of HR-Killer1 and identification of small molecules for cancer therapy and enhanced gene editing using CRISPR/Cas9-based DNA repair strategies

Nominated PICIHR2017Project Grant

Principal investigators: Dellaire, Graham P

Keywords: Alternative Non-Homologous End Joining; Cancer Therapy; Crispr/Cas9; Dna Repair; Gene Editing; High-Content Screening; Homologous Recombination; Small Molecule Screening; Synthetic Lethality

$1,063,350

The role of ubiquitin-like proteins (UBLs) in DNA repair in vertebrates

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Dellaire, Graham

$170,000

A Total Internal Reflection Fluorescence (TIRF) Microscope for the Maritimes

Co-investigatorNSERC2014Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: McCormick, Craig

$53,522

Using the zebrafish as a pre-clinical animal tumour model for drug discovery and the evaluation of anti-leukemia agents

Principal investigatorNSERC2012Collaborative Health Research Projects

Principal investigators: Dellaire, Graham

$199,999

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Graham Dellaire

Research

Latest papers

Latest funding

Epigenetic control of telomeric RNA maintains heterochromatin in telomerase-driven cancers.

Membrane curvature elastic stress triggers recruitment of PML-II onto the inner nuclear membrane.

The evolutionarily conserved PRP4K-CHMP4B/vps32 splicing circuit regulates autophagy.

The proximity interactome of PML isoforms I and II under fatty acid stress.

Retraction Note: A mechanism for the suppression of homologous recombination in G1 cells.

Telomeric SUMO level influences the choices of APB formation pathways and ALT efficiency.

Telomeric SUMO level influences the choices of APB formation pathways and ALT efficiency.

From biosynthesis and beyond-Loss or overexpression of the cytokinin synthesis gene, iptA, alters cytokinesis and mitochondrial and amino acid metabolism in Dictyostelium discoideum.

Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope.

Mechanisms for assembly of the nucleoplasmic reticulum.

Determining how PRP4K insufficiency impacts cancer signaling and therapy responses

Characterizing the evolutionarily conserved functions of the pre-mRNA processing factor 4 kinase in cellular stress

Evolutionary molecular biology of the interplay between the DNA damage response and innate immunity

1st Canadian Environmental Exposures in Cancer (CE2C) Network Meeting

Super-resolution radial fluctuation microscope for 4D imaging of cells and cellular dynamics

Identifying the regulatory functions of nuclear lipid synthesis and storage pathways

Characterization of HR-Killer1 and identification of small molecules for cancer therapy and enhanced gene editing using CRISPR/Cas9-based DNA repair strategies

The role of ubiquitin-like proteins (UBLs) in DNA repair in vertebrates

A Total Internal Reflection Fluorescence (TIRF) Microscope for the Maritimes

Using the zebrafish as a pre-clinical animal tumour model for drug discovery and the evaluation of anti-leukemia agents

Frequent collaborators

Jean-Yves Masson

Christopher Eskiw

Alexandre Orthwein

Jacques Simard

Daniel Durocher

Alison Thompson

Shahid Ahmed

Amina Zoubeidi

Gary Groot

Anand Krishnan

Aneesh Thakur

Francesca Di Cara

Kirill Rosen

Yannick Doyon

Eric Milot

Michael Ha

Alain Nepveu

Paola Marcato

Clinton Campbell

Andrew Freywald

Brent Johnston

Roy Duncan

Yuzhuo Wang

Sabine Mai

Craig McCormick