Faculty profile

Manuel Mattheisen

ResearcherPsychiatryDalhousie University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Dalhousie University directory, so their courses may be missing. Find their university profile.

Manuel Mattheisen

Researcher

Psychiatry

Health Sciences

Dalhousie University

Halifax, Nova Scotia, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
40 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 2 research grants (2 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

135

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Capacity Development Data Services Edia Indigenous Allyship Learning Health Systems Patient Oriented Research People With Lived/Living Experience Sex & Gender

Latest papers

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.
Nature genetics · 2026
Genomic meta-analyses of binge-eating behavior and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes.
Nature. Mental health · 2026
Mapping the genetic landscape across 14 psychiatric disorders.
Nature · 2026

All 42 publications

Latest funding

SPOR SUPPORT Unit Funding Extension
CIHR · 2025 · Principal investigator
$2,931,046
The GAYA Study - Exploring the Genetic Architecture of Youth Anxiety
CIHR · 2021 · Principal investigator
$1,078,652
Clinical and genetic factors in response to treatment of bipolar disorder
CIHR · 2019 · Co-investigator
$753,526

All 3 grants and awards

42 publications.

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.

Strom NI, Verhulst B, Bacanu SA, Cheesman R, Purves KL, Gedik H, Mitchell BL, Kwong AS, Faucon AB, Singh K, Medland S, Colodro-Conde L, Krebs K, Hoffmann P, Herms S, Gehlen J, Ripke S, Awasthi S, Palviainen T, Tasanko EM, Peterson RE, Adkins DE, Shabalin AA, Adams MJ, Iveson MH, Campbell A, Thomas LF, Winsvold BS, Drange OK, Børte S, Ter Kuile AR, Naamanka J, Nguyen TH, Meier SM, Corfield EC, Hannigan L, Levey DF, Czamara D, Weber H, Choi KW, Pistis G, Couvy-Duchesne B, Van der Auwera S, Teumer A, Karlsson R, Garcia-Argibay M, Lee D, Wang R, Bjerkeset O, Stordal E, Bäckman J, Salum GA, Zai CC, Kennedy JL, Zai G, Tiwari AK, Heilmann-Heimbach S, Schmidt B, Kaprio J, Kennedy MM, Boden J, Havdahl A, Middeldorp CM, Lopes FL, Akula N, McMahon FJ, Binder EB, Fehm L, Ströhle A, Castelao E, Tiemeier H, Stein DJ, Whiteman D, Olsen C, Fuller Z, Wang X, Wray NR, Byrne EM, Lewis G, Timpson NJ, Davis LK, Hickie IB, Gillespie NA, Milani L, Schumacher J, Woldbye DP, Forstner AJ, Nöthen MM, Hovatta I, Horwood J, Copeland WE, Maes HH, McIntosh AM, Andreassen OA, Zwart JA, Mors O, Børglum AD, Mortensen PB, Ask H, Reichborn-Kjennerud T, Najman JM, Stein MB, Gelernter J, Milaneschi Y, Penninx BW, Boomsma DI, Maron E, Erhardt-Lehmann A, Rück C, Kircher TT, Melzig CA, Alpers GW, Arolt V, Domschke K, Smoller JW, Preisig M, Martin NG, Lupton MK, Luik AI, Reif A, Grabe HJ, Larsson H, Magnusson PK, Oldehinkel AJ, Hartman CA, Breen G, Docherty AR, Coon H, Conrad R, Lehto K, Veterans Affairs Million Veteran Program, FinnGen, 23andMe Research Team, Deckert J, Eley TC, Mattheisen M, Hettema JM

Nature genetics2026

DOI: 10.1038/s41588-025-02485-8 PMID: 41634414

Genomic meta-analyses of binge-eating behavior and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes.

Termorshuizen JD, Davies HL, Lee SH, Dennis JK, Hübel C, Johnson JS, Lu Y, Munn-Chernoff MA, Peters T, Qi B, Schaumberg KE, Signer RH, Singh K, Ter Kuile AR, Thornton LM, Xu J, Yao S, Yilmaz Z, Zhang R, Zvrskovec J, Abdulkadir M, Ayorech Z, Corfield EC, Havdahl A, Krebs K, Mack TM, Niarchou M, Palviainen T, Sealock JM, Baker JH, Bergen AW, Birgegård A, Boraska Perica V, Bühren K, Burghardt R, Cassina M, Castellini G, Collantoni E, Crowley JJ, Danner UN, Degenhardt F, DeSocio JE, Dina C, Dmitrzak-Węglarz M, Duncan LE, Egberts KM, Foretova L, Giegling I, Gonidakis F, Gordon SD, Grove J, Guillaume S, Guintivano JD, Hartmann AM, Hatzikotoulas K, Herms S, Imgart H, Jiménez-Murcia S, Julià A, Kalsi G, Kaminská D, Karhunen LJ, Kennedy HL, Kiezebrink KM, Kolb T, Larsen JT, Li D, Lilenfeld L, Maj M, Mattingsdal M, Meneguzzo P, Miller AL, Mitchell KS, Monteleone AM, Olsen CM, Padyukov L, Parker R, Pettie MA, Pinto D, Raevuori A, Ripatti S, Roberts ME, Santonastaso P, Savva A, Schmidt UH, Schosser A, Seitz J, Slachtova LL, Slopien A, Sorbi S, Straub PS, Szatkiewicz JP, Tam FI, Tenconi E, Tortorella A, Tsitsika A, van Elburg AA, Wagner G, Watson HJ, Adan RA, Alfredsson L, Andreassen OA, Ask H, Børglum AD, Brandt HA, Collier D, Crawford S, Crow S, Davis LK, de Zwaan M, Dedoussis G, Dick DM, Ehrlich S, Estivill X, Favaro A, Fernández-Aranda F, Fischer K, Forstner AJ, Gorwood P, Hakonarson H, Hebebrand J, Herpertz-Dahlmann B, Hinney A, Hudson JI, Johnson C, Jordan J, Kaplan AS, Kaprio J, Karwautz AF, Kas MJ, Kaye WH, Kennedy JL, Kennedy MA, Keski-Rahkonen A, Kim YR, Klump KL, Landén M, Le Hellard S, Lehto K, Li QS, Lissowska J, Luykx JJ, Maguire SL, Martin NG, Mattheisen M, Medland SE, Mehler P, Micali N, Mitchell JE, Monteleone P, Mortensen PB, Nacmias B, Ophoff RA, Papezova H, Pedersen NL, Petersen LV, Rajcsanyi LS, Ramoz N, Reichborn-Kjennerud T, Ricca V, Ripke S, Rujescu D, Rybakowski F, Scherer SW, Slof-Op 't Landt MC, Steiger H, Sullivan PF, Świątkowska B, van Furth EF, Wade TD, Werge T, Whiteman DC, Woodside DB, Wu YK, Zipfel S, Disorders Working Group of the Psychiatric Genomics Consortium, Estonian Biobank (EstBB), Bulik CM, Huckins LM, Breen G, Coleman JRI, Disorders Working Group of the Psychiatric Genomics Consortium

Nature. Mental health2026

DOI: 10.1038/s44220-026-00698-2 PMID: 42718672

Mapping the genetic landscape across 14 psychiatric disorders.

Grotzinger AD, Werme J, Peyrot WJ, Frei O, de Leeuw C, Bicks LK, Guo Q, Margolis MP, Coombes BJ, Batzler A, Pazdernik V, Biernacka JM, Andreassen OA, Anttila V, Børglum AD, Breen G, Cai N, Demontis D, Edenberg HJ, Faraone SV, Franke B, Gandal MJ, Gelernter J, Hatoum AS, Hettema JM, Johnson EC, Jonas KG, Knowles JA, Koenen KC, Maihofer AX, Mallard TT, Mattheisen M, Mitchell KS, Neale BM, Nievergelt CM, Nurnberger JI, O'Connell KS, Peterson RE, Robinson EB, Sanchez-Roige SS, Santangelo SL, Scharf JM, Stefansson H, Stefansson K, Stein MB, Strom NI, Thornton LM, Tucker-Drob EM, Verhulst B, Waldman ID, Walters GB, Wray NR, Yu D, Anxiety Disorders Working Group of the Psychiatric Genomics Consortium, Attention-Deficit/Hyperactivity Disorder (ADHD) Working Group of the Psychiatric Genomics Consortium, Autism Spectrum Disorders Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Nicotine Dependence GenOmics (iNDiGO) Consortium, Obsessive-Compulsive Disorder and Tourette Syndrome Working Group of the Psychiatric Genomics Consortium, Post-Traumatic Stress Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, Lee PH, Kendler KS, Smoller JW

Nature2026

DOI: 10.1038/s41586-025-09820-3 PMID: 41372416

Persistent tic disorders are associated with 17q12 duplications.

Halvorsen MW, Wang S, Miller-Fleming TW, Yu D, Topaloudi A, de Schipper E, Bäckman J, Mataix-Cols D, Rück C, Mahjani B, Buxbaum JD, Grice DE, Cavallari LH, Angiolillo DJ, Franchi F, Davis LK, Han L, Ruderfer DM, Psychiatric Genomics Consortium OCD-TS Working Group (PGC-OCD-TS), TS-EUROTRAIN, EMTICS, Tourette International Collaborative Genetics (TIC Genetics), Tourette Association of America International Consortium of Genetics (TAAICG), Nordic OCD and Related Disorders Consortium (NORDIC), Dietrich A, Hoekstra PJ, Mattheisen M, Porras LM, Giusti-Rodriguez P, Mathews CA, Paschou P, Scharf JM, Willsey AJ, Crowley JJ

Molecular psychiatry2026

DOI: 10.1038/s41380-026-03849-0 PMID: 42749776

Genome-Wide Association Study of Symptom Change Following Cognitive Behavioral Therapy for Common Mental Disorders.

Bäckman J, Kravchenko O, Halvorsen M, de Schipper E, Ivanova E, Kaldo V, Isacsson NH, Eide TO, Höffler KD, Mattheisen M, Hansen B, Kvale G, Hagen K, Haavik J, Mataix-Cols D, Crowley JJ, Wallert J, Rück C, Nordic OCD and Related Disorders Consortium (NORDiC)

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics2026

DOI: 10.1002/ajmg.b.70015 PMID: 41804033

Causal inference in psychiatric research: how to critically evaluate and interpret mendelian randomization studies.

Garcia-Argibay M, Wootton RE, Larsson H, Mattheisen M, Polimanti R, Meier S

Molecular psychiatry2026

DOI: 10.1038/s41380-026-03484-9 PMID: 41673464

Altered neurodevelopmental trajectories of brain structure in Tourette syndrome and Chronic Tic Disorders.

Jin Y, Guo Y, Koller JM, Grossen SC, Uhlmann A, Forde NJ, Zouki JJ, Torrecuso R, Mueller K, Martin-Rodriguez JF, Franco-Rosado P, Grothe M, Cramer C, Büning AK, Eichele H, Palmucci S, Prato A, Saia F, Tommasin S, Conte G, Schindlbeck KA, Ganos C, Zimmermann S, Veselinovic T, Worbe Y, Hartmann A, Topaloudi A, Kaka M, Chen G, Zhong Q, Zhang Y, Szejko N, Janik P, Debes NM, Tumer Z, Wolańczyk T, Heiman GA, Stefansson H, Ask H, Andreassen O, Børglum AD, Buxbaum JD, Corfield EC, Daly M, Grice DE, Mataix-Cols D, Palotie A, Rück C, Halvorsen MW, Davis LK, Crowley JJ, Mattheisen M, Yu D, Mathews CA, Scharf JM, members of the Tourette International TS-EUROTRAIN/TSGeneSEE, TAA Neuroimaging Consortium, Collaborative Genetics consortium, TAAICG, EMTICS, ENIGMA-TS Working Group, Stein DJ, Neuner I, Musil R, Cardona F, Cath D, Veltman DJ, Silk TJ, Munchau A, Verrel J, Brandt VC, Hershey T, Greene DJ, Schlaggar BL, Buitelaar J, Franke B, Thomopoulos S, Rizzo R, Dietrich A, Hoekstra PJ, Mir P, Roessner V, van den Heuvel OA, Mueller-Vahl K, Möller H, Jahanshad N, Thompson PM, Black KJ, Paschou P

medRxiv : the preprint server for health sciences2026

DOI: 10.64898/2026.05.16.26353368 PMID: 42238458

Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Strom NI, Gerring ZF, Galimberti M, Yu D, Halvorsen MW, Abdellaoui A, Rodriguez-Fontenla C, Sealock JM, Bigdeli T, Coleman JR

Nature Genetics2025100 citationsOpen Access

DOI: 10.1038/s41588-025-02189-z PMID: W4410325451

Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research.

Cai N, Verhulst B, Andreassen OA, Buitelaar J, Edenberg HJ, Hettema JM, Gandal M, Grotzinger A, Jonas K, Lee P, Mallard TT, Mattheisen M, Neale MC, Nurnberger JI, Peyrot WJ, Tucker-Drob EM, Smoller JW, Kendler KS

Molecular psychiatry2025

DOI: 10.1038/s41380-024-02878-x PMID: 39730880

A burden of rare copy number variants in obsessive-compulsive disorder.

Halvorsen MW, de Schipper E, Bäckman J, Strom NI, Hagen K, Nordic OCD and Related Disorders Consortium (NORDiC), Lindblad-Toh K, Karlsson EK, Pedersen NL, Wallert J, Bulik CM, Fundín B, Landén M, Kvale G, Hansen B, Haavik J, Mattheisen M, Rück C, Mataix-Cols D, Crowley JJ

Molecular psychiatry2025

DOI: 10.1038/s41380-024-02763-7 PMID: 39463448

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Manuel Mattheisen

Research

Latest papers

Latest funding

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.

Genomic meta-analyses of binge-eating behavior and anorexia nervosa yield insights into the unique and shared biology of eating disorder phenotypes.

Mapping the genetic landscape across 14 psychiatric disorders.

Persistent tic disorders are associated with 17q12 duplications.

Genome-Wide Association Study of Symptom Change Following Cognitive Behavioral Therapy for Common Mental Disorders.

Causal inference in psychiatric research: how to critically evaluate and interpret mendelian randomization studies.

Altered neurodevelopmental trajectories of brain structure in Tourette syndrome and Chronic Tic Disorders.

Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research.

A burden of rare copy number variants in obsessive-compulsive disorder.

SPOR SUPPORT Unit Funding Extension

The GAYA Study - Exploring the Genetic Architecture of Youth Anxiety

Clinical and genetic factors in response to treatment of bipolar disorder

Frequent collaborators

Sandra Meier

Jennifer Crosbie

James Kennedy

Paul Sandor

Alexa Bagnell

Guillaume Lettre

Jean-Claude Tardif

Jean-Claude Tardif

Louis Pérusse

Kathleen Askland

Noam Soreni

Patricia Lingley-Pottie

Rita Orji

Marie-Claude Vohl

Howard Steiger

Russell Schachar

Taylor Hatchard

Karen Rowa

Khrista Boylan

Jehannine Austin

Patrick McGrath