This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Dalhousie University directory, so their courses and email address may be missing. Find their university profile.
Latest papers
Targeting TRPML3 inhibits proliferation and invasion, and enhances doxorubicin sensitivity by disrupting lysosomal acidification and mitochondrial function in triple-negative breast cancer.
Biochimica et biophysica acta. Molecular cell research · 2025
Proton-Activated Chloride Channel: Physiology and Disease.
Frontiers in bioscience (Landmark edition) · 2023
VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1.
Nature microbiology · 2019
Latest funding
- $47,000
Ion channels in endolysosome physiology and autophagy
NSERC · 2024 · Principal investigator
- $814,725
Lysosomal TRPML Channels in Myogenesis and Centronuclear Myopathies
CIHR · 2023 · Nominated PI
- $634,950
Functional crosstalk between TRPML3 and BK in autophagy induction and pathogen defense
CIHR · 2017 · Nominated PI
4 publications.
Targeting TRPML3 inhibits proliferation and invasion, and enhances doxorubicin sensitivity by disrupting lysosomal acidification and mitochondrial function in triple-negative breast cancer.
Gomes GMA, Xu M, Syeda AKR, Raudonis R, Almasi S, Vijayan VV, Gujar S, Dong X, Cheng Z, Pulinilkunnil T, El Hiani Y
Proton-Activated Chloride Channel: Physiology and Disease.
Peng F, Wu Y, Dong X, Huang P
VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1.
Capurro MI, Greenfield LK, Prashar A, Xia S, Abdullah M, Wong H, Zhong XZ, Bertaux-Skeirik N, Chakrabarti J, Siddiqui I, O'Brien C, Dong X, Robinson L, Peek RM, Philpott DJ, Zavros Y, Helmrath M, Jones NL
LYZL6, an acidic, bacteriolytic, human sperm-related protein, plays a role in fertilization.
Huang P, Li W, Yang Z, Zhang N, Xu Y, Bao J, Jiang D, Dong X
Ion channels in endolysosome physiology and autophagy
Principal investigators: Dong, Xianping
Keywords: endolysosome; trpml; autophagy; mtor; calcium; ion channel
Lysosomal TRPML Channels in Myogenesis and Centronuclear Myopathies
Principal investigators: Dong, Xianping
Keywords: Ion Channel; Lysosome; Mtm1; Myopathy; Skeletal Muscle; Trpml1
Functional crosstalk between TRPML3 and BK in autophagy induction and pathogen defense
Principal investigators: Dong, Xianping
Keywords: Autophagy; Bk Channel; Endolysosome; Endolysosome Ca2+; Mtorc1; Trpml3; Whole-Endolysosome Patch-Clamp
TRPML1 in intracellular Fe2+ and Ca2+ homeostasis/signaling
Principal investigators: Dong, Xianping
Keywords: Autophagy; Ca2+/Fe2+ Imaging; Ca2+/Fe2+ Signaling; Cellular Biology; Electrophysiology; Ion Channel; Lysosomal Patch-Clamping; Lysosome; Neurobiology
TRPML1 in intracellular Fe2+ and Ca2+ homeostasis/signaling
Principal investigators: Dong, Xianping
Keywords: Autophagy; Ca2+/Fe2+ Imaging; Ca2+/Fe2+ Signaling; Cell Biology; Electrophysiology; Ion Channel; Lysosomal Patch-Clamping; Lysosome; Neurobiology
TRPML1 in intracellular Fe2+ and Ca2+ homeostasis/signaling
Principal investigators: Dong, Xianping
Keywords: Autophagy; Ca2+/Fe2+ Imaging; Ca2+/Fe2+ Signaling; Cell Biology; Electrophysiology; Ion Channel; Lysosomal Patch-Clamping; Lysosome; Neurobiology
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Physiology and Biophysics
- Surgery and Cancer
- Department of Biochemistry
- Pathology
- Biochemistry and Molecular Biology
- Microbiology and Immunology
Co-authors at Dalhousie University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Zhenyu Cheng
Microbiology and Immunology
1 shared papers, latest 2025
Shashi Gujar
Pathology
1 shared papers, latest 2025
Thomas Pulinilkunnil
Biochemistry and Molecular Biology
1 shared papers, latest 2025
Catherine O'Brien
Surgery and Cancer
1 shared papers, latest 2019
Lisa Robinson
Department of Biochemistry
1 shared papers, latest 2019
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