Faculty profile

Assistant Clinical Professor (Adjunct)Family MedicineMcMaster University

26 publications.

01

Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection

Lee AJ, Feng E, Chew MV, Balint E, Poznanski SM, Giles E, Zhang A, Marzok A, Revill SD, Vahedi F

PLoS Pathogens202211 citationsFirst author
02

Postbiotics for NOD2 require nonhematopoietic RIPK2 to improve blood glucose and metabolic inflammation in mice

Cavallari JF, Barra NG, Foley KP, Lee A, Duggan BM, Henriksbo BD, Anhê FF, Ashkar AA, Schertzer JD

American Journal of Physiology - Endocrinology and Metabolism202064 citationsOpen Access
03

IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity

Karimi Y, Giles EC, Vahedi F, Chew MV, Nham T, Loukov D, Lee AJ, Bowdish DM, Ashkar AA

Innate Immunity202025 citations
04

Thermal Stabilization of Viral Vaccines in Low-Cost Sugar Films

Leung V, Mapletoft J, Zhang A, Lee A, Vahedi F, Chew M, Szewczyk A, Jahanshahi-Anbuhi S, Ang J, Cowbrough B

Scientific Reports201957 citationsOpen Access
05

Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production

Lee AJ, Mian F, Poznanski SM, Stackaruk M, Chan T, Chew MV, Ashkar AA

Frontiers in Immunology201935 citationsFirst author
06

IL-15 and IFN-γ signal through the ERK pathway to inhibit HCV replication, independent of type I IFN signaling

Vahedi F, Lee AJ, Collins SE, Chew MV, Lusty E, Chen B, Dubey A, Richards CD, Feld JJ, Russell RS

Cytokine201912 citations
07

The Dual Nature of Type I and Type II Interferons

Lee AJ, Ashkar AA

Frontiers in Immunology2018673 citationsFirst author
08

Expanded CD56superbrightCD16+ NK cells from ovarian cancer patients are cytotoxic against autologous tumor in a patient-derived xenograft murine model

Poznanski SM, Nham T, Chew MV, Lee AJ, Hammill JA, Fan IY, Butcher M, Bramson JL, Lee DA, Hirte HW

Cancer immunology research201850 citations
09

Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells

Nham T, Poznanski SM, Fan IY, Shenouda MM, Chew MV, Lee AJ, Vahedi F, Karimi Y, Butcher M, Lee DA

Cancer Immunology, Immunotherapy201846 citations
10

Ex Vivo-expanded Natural Killer Cells Derived From Long-term Cryopreserved Cord Blood are Cytotoxic Against Primary Breast Cancer Cells

Nham T, Poznanski SM, Fan IY, Vahedi F, Shenouda MM, Lee AJ, Chew MV, Hogg RT, Lee DA, Ashkar AA

Journal of Immunotherapy201835 citations
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Subject: Prospective PhD student Dear Professor Lee, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection" (2022), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]
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